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Human SLC1A5 Alexa Fluor® 700-conjugated Antibody

Catalog #: FAB11603N Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
FAB11603N-100UG

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Human SLC1A5 Alexa Fluor® 700-conjugated Antibody Summary

Species Reactivity
Human
Specificity
Detects a synthetic peptide corresponding to residues near amino acid 500 of human SLC1A5 protein by Direct ELISA.
Source
Monoclonal Mouse IgG2b Clone # 1085750
Purification
Protein A or G purified
Immunogen
Synthetic Peptide
Accession # Q15758
Formulation
Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide
Label
Alexa Fluor 700 (Excitation= 675-700 nm, Emission= 723 nm)

Applications

Recommended Concentration
Sample
Western Blot
Optimal dilution of this antibody should be experimentally determined.
 
Immunohistochemistry
Optimal dilution of this antibody should be experimentally determined.
 
Immunocytochemistry
Optimal dilution of this antibody should be experimentally determined.
 

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Reconstitution Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

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Preparation and Storage

Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied

Background: SLC1A5

SLC1A5 is a sodium dependent antiporter also known as ASCT2 (ASC amino acid Transporter2).  It is a member of the solute carrier (SLC) superfamily of transporters and plays an important role in tumors.  It is one of the 3 proteins, including SLC7A5 and SLC3A2, that are among the highest differentially expressed genes in activated lymphocytes and cancerous cells.  Pharmacological inhibition of SLC1A5 was found to abrogate the effector functions of NK cells.  In a pancancer analysis of SLC1A5, it has been demonstrated to be a prognostic biomarker in cancer patients.

Long Name
SLC1A5
Entrez Gene IDs
6510 (Human); 20514 (Mouse); 292657 (Rat)
Alternate Names
AAAT; Alanine/serine/cysteine transporter 2; ASC amino acid transporter-2; ASCT2; ATB(0); ATBO; baboon M7 virus receptor; M7V1; M7VS1; neutral amino acid transporter B; neutral amino acid transporter B(0); R16; RD114 virus receptor; RD114/simian type D retrovirus receptor; RDR; RDRC; SLC1A5; Sodium-dependent neutral amino acid transporter type 2; solute carrier family 1 (neutral amino acid transporter), member 5; Solute carrier family 1 member 5

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