Key Product Details

Species Reactivity

Human

Applications

Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Rat IgG2A Clone # 376409
View all TAPP1 Primary Antibodies »

Product Specifications

Immunogen

E. coli-derived recombinant human TAPP1
Pro2-Val404
Accession # Q9HB21

Specificity

Detects human TAPP1 in direct ELISAs and Western blots.

Clonality

Monoclonal

Host

Rat

Isotype

IgG2A

Applications for Human TAPP1 Antibody

Application
Recommended Usage

Western Blot

1 µg/mL
Sample: Recombinant Human TAPP1

Formulation, Preparation, and Storage

Purification

Protein A or G purified from hybridoma culture supernatant

Reconstitution

Reconstitute at 0.5 mg/mL in sterile PBS. For liquid material, refer to CoA for concentration.

Formulation

Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.

Shipping

Lyophilized product is shipped at ambient temperature. Liquid small pack size (-SP) is shipped with polar packs. Upon receipt, store immediately at the temperature recommended below.

Stability & Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.

Calculators

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

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Background: TAPP1

TAPP1, gene name PLEKHA1 (pleckstrin homology family A, member 1) is a 70‑75 kDa cytoplasmic adaptor protein that is membrane-associated after binding of the phosphoinositide, PtdIns(3,4)P2. The 404 aa human TAPP1 shares 76% aa identity with mouse TAPP1. It is expressed most highly in skeletal muscle, spleen, lung, thymus and placenta. TAPP1 interacts with cytoskeletal syntrophins, colocalizing in membrane ruffles following PDGF treatment in transfected NIH‑3T3 cells. TAPP1 and the related TAPP2 appear to play a role in B and T cell activation.

Long Name

Tandem PH Domain Containing Protein 1

Alternate Names

PLEKHA1

Entrez Gene IDs

59338 (Human); 101476 (Mouse); 361659 (Rat)

Gene Symbol

PLEKHA1

UniProt

Q9HB21

Additional TAPP1 Products

Product Documents for Human TAPP1 Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Note: Certificate of Analysis not available for kit components.

Download SDS

Product Specific Notices for Human TAPP1 Antibody

For research use only

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FAQs

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