TLR4, also known as CD284, is a 100 kDa transmembrane pattern recognition receptor. It associates with MD-2 on monocytes, macrophages, dendritic cells, and B cells where it functions as a receptor for bacterial endotoxin/lipopolysaccharide (LPS). LPS is extracted from circulating CD14-LPS complexes and triggers a TLR4 mediated inflammatory response.
Human TLR4 (NP_612564) VersaClone cDNA
R&D Systems | Catalog # RDC0371
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Background: TLR4
Long Name
Toll-like Receptor 4
Alternate Names
CD284
Gene Symbol
TLR4
UniProt
Additional TLR4 Products
Product Documents for Human TLR4 (NP_612564) VersaClone cDNA
Certificate of Analysis
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Product Specific Notices for Human TLR4 (NP_612564) VersaClone cDNA
For research use only
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