• Assay Length
    3.5 hours or 4.5 hours
  • Sample Type & Volume Required Per Well
    Cell Culture Supernates (200 uL), Serum (200 uL), EDTA Plasma (200 uL), Heparin Plasma (200 uL), Citrate Plasma (200 uL)
  • Sensitivity
    5.5 pg/mL
  • Assay Range
    15.6 - 1,000 pg/mL (Cell Culture Supernates, Serum, EDTA Plasma, Heparin Plasma, Citrate Plasma)
  • Specificity
    Natural and recombinant human TNF-alpha
  • Cross-reactivity
    < 0.5% cross-reactivity observed with available related molecules.< 50% cross-species reactivity observed with species tested.
  • Interference
    No significant interference observed with available related molecules.
Control Available
QC01-1, Quantikine Immunoassay Control Group 1 - Please Inquire
Product Summary
The Quantikine Human TNF-alpha Immunoassay is a 3.5 or 4.5 hour solid phase ELISA designed to measure human TNF-alpha in cell culture supernates, serum, and plasma. It contains E. coli-derived recombinant human TNF-alpha and antibodies raised against this protein. It has been shown to accurately quantitate the recombinant factor. Results obtained with naturally occurring TNF-alpha samples showed linear curves that were parallel to the standard curves obtained using the Quantikine kit standards. These results indicate that this kit can be used to determine relative mass values for natural human TNF-alpha.

Precision
Intra-Assay Precision (Precision within an assay) Three samples of known concentration were tested on one plate to assess intra-assay precision.
Inter-Assay Precision (Precision between assays) Three samples of known concentration were tested in separate assays to assess inter-assay precision.
Serum, EDTA Plasma, Heparin Plasma, Citrate Plasma
Intra-Assay Precision Inter-Assay Precision
Sample123123
n202020202020
Mean48.131758745.8301587
Standard Deviation2.513.227.13.413.731.6
CV%5.24.24.67.44.65.4

Cell Culture Supernates
Intra-Assay Precision Inter-Assay Precision
Sample123123
n202020202020
Mean41.228154643.8283567
Standard Deviation2.212.527.3324.741.5
CV%5.34.456.88.77.3

Recovery

The recovery of TNF-alpha spiked to three different levels throughout the range of the assay in various matrices was evaluated.

Sample Type Average % Recovery Range %
Cell Culture Media (n=5) 98 91-109
Citrate Plasma (n=5) 106 89-123
EDTA Plasma (n=5) 110 98-128
Heparin Plasma (n=5) 101 89-115
Serum (n=5) 107 94-119
Serum (n=)
Linearity
To assess the linearity of the assay, five samples were spiked with high concentrations of TNF-alpha in various matrices and diluted with the appropriate Calibrator Diluent to produce samples with values within the dynamic range of the assay.
Human TNF-alpha Quantikine ELISA Kit
Preparation and Storage
  • Storage
    Store the unopened product at 2 - 8 °C. Do not use past expiration date.
Background: TNF-alpha

Tumor necrosis factor alpha (TNF-α), also known as cachectin and TNFSF2, is the prototypic ligand of the TNF superfamily. It is a pleiotropic molecule that plays a central role in inflammation, apoptosis, and immune system development. TNF-α is produced by a wide variety of immune and epithelial cell types. Human TNF-α consists of a 35 amino acid (aa) cytoplasmic domain, a 21 aa transmembrane segment, and a 177 aa extracellular domain (ECD). Within the ECD, human TNF-α shares 97% aa sequence identity with rhesus and 71% - 92% with bovine, canine, cotton rat, equine, feline, mouse, porcine, and rat TNF-α. The 26 kDa type 2 transmembrane protein is assembled intracellularly to form a noncovalently linked homotrimer. Ligation of this complex induces reverse signaling that promotes lymphocyte costimulation but diminishes monocyte responsiveness.

Cleavage of membrane bound TNF-α by TACE/ADAM17 releases a 55 kDa soluble trimeric form of TNF-α. TNF-α trimers bind the ubiquitous TNF RI and the hematopoietic cell-restricted TNF RII, both of which are also expressed as homotrimers. TNF-α regulates lymphoid tissue development through control of apoptosis. It also promotes inflammatory responses by inducing the activation of vascular endothelial cells and macrophages. TNF-α is a key cytokine in the development of several inflammatory disorders. It contributes to the development of type 2 diabetes through its effects on insulin resistance and fatty acid metabolism.

    • Long Name
      Tumor Necrosis Factor alpha
    • Entrez Gene IDs
      7124 (Human); 21926 (Mouse); 24835 (Rat); 397086 (Porcine); 280943 (Bovine); 403922 (Canine); 100033834 (Equine); 493755 (Feline); 100009088 (Rabbit);
    • Alternate Names
      APC1 protein; Cachectin; Cachetin; DIF; TNF; TNF, monocyte-derived; tnfa; tnf-a; TNFalpha; TNF-alpha; TNF-alphacachectin; TNFATNF, macrophage-derived; TNFSF1A; TNFSF2; TNFSF2TNF superfamily, member 2; tumor necrosis factor (TNF superfamily, member 2); tumor necrosis factor alpha; Tumor necrosis factor ligand superfamily member 2; tumor necrosis factor; tumor necrosis factor-alpha;
    Related Research Areas
    Citations:

    R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

    208 Citations: Showing 1 - 10
    Filter your results:

    Species
    Sample Type
    1. Function of Inhibitor of Brutons Tyrosine Kinase Isoform ? (IBTK?) in Nonalcoholic Steatohepatitis links Autophagy and the Unfolded Protein Response
      Authors: JA Willy, SK Young, AL Mosley, S Gawrieh, JL Stevens, HC Masuoka, RC Wek
      J. Biol. Chem., 2017;0(0):.
      Species: Human
      Sample Type: Cell Culture Supernates
    2. PU.1 serves a critical role in the innate defense against Aspergillus�fumigatus via dendritic cell-associated C-type lectin receptor-1 and toll-like receptors-2 and 4 in THP-1-derived macrophages
      Authors: C Liu, M Wang, W Sun, F Cai, S Geng, X Su, Y Shi
      Mol Med Rep, 2017;0(0):.
      Species: Human
      Sample Type: Cell Culture Supernates
    3. Surfactant protein A is expressed in the central nervous system of rats with experimental autoimmune encephalomyelitis, and suppresses inflammation in human astrocytes and microglia
      Authors: X Yang, J Yan, J Feng
      Mol Med Rep, 2017;0(0):.
      Species: Human
      Sample Type: Cell Culture Supernates
    4. Comparison of fibrin glue and Vicryl sutures in conjunctival autografting for pterygium surgery
      Authors: X Wang, Y Zhang, L Zhou, R Wei, L Dong
      Mol. Vis., 2017;23(0):275-285.
      Species: Human
      Sample Type: Tears
    5. Toll-like receptor polymorphisms compromise the inflammatory response against bacterial antigen translocation in cirrhosis
      Authors: P Piñero, O Juanola, E Caparrós, P Zapater, P Giménez, JM González-N, J Such, R Francés
      Sci Rep, 2017;7(0):46425.
      Species: Human
      Sample Type: Serum
    6. The long non-coding RNA TP73-AS1 modulates HCC cell proliferation through miR-200a-dependent HMGB1/RAGE regulation
      Authors: S Li, Y Huang, Y Huang, Y Fu, D Tang, R Kang, R Zhou, XG Fan
      J. Exp. Clin. Cancer Res., 2017;36(1):51.
      Species: Human
      Sample Type: Cell Culture Supernates
    7. Human and feline adipose-derived mesenchymal stem cells have comparable phenotype, immunomodulatory functions, and transcriptome
      Authors: KC Clark, FA Fierro, EM Ko, NJ Walker, B Arzi, CG Tepper, H Dahlenburg, A Cicchetto, A Kol, L Marsh, WJ Murphy, N Fazel, DL Borjesson
      Stem Cell Res Ther, 2017;8(1):69.
      Species: Human
      Sample Type: Cell Culture Supernates
    8. Serum high mobility group box-1 and osteoprotegerin levels are associated with peripheral arterial disease and critical limb ischemia in type 2 diabetic subjects
      Authors: S Giovannini, G Tinelli, F Biscetti, G Straface, F Angelini, D Pitocco, L Mucci, R Landolfi, A Flex
      Cardiovasc Diabetol, 2017;16(1):99.
      Species: Human
      Sample Type: Serum
    9. Overexpression of GLP-1 receptors suppresses proliferation and cytokine release by airway smooth muscle cells of patients with chronic obstructive pulmonary disease via activation of ABCA1
      Authors: YH Sun, L He, MY Yan, RQ Zhao, B Li, F Wang, Y Yang, HP Yu
      Mol Med Rep, 2017;0(0):.
    10. Correlation between plasma endothelin-1 levels and severity of septic liver failure quantified by maximal liver function capacity (LiMAx test). A prospective study
      Authors: MF Kaffarnik, N Ahmadi, JF Lock, T Wuensch, J Pratschke, M Stockmann, M Malinowski
      PLoS ONE, 2017;12(5):e0178237.
      Species: Human
      Sample Type: Plasma
    11. High serum resistin associates with intrahepatic inflammation and necrosis: an index of disease severity for patients with chronic HBV infection
      Authors: Z Meng, Y Zhang, Z Wei, P Liu, J Kang, Y Zhang, D Ma, C Ke, Y Chen, J Luo, Z Gong
      BMC Gastroenterol, 2017;17(1):6.
      Species: Human
      Sample Type: Serum
    12. The increased concentration of macrophage migration inhibitory factor in serum and cerebrospinal fluid of patients with tick-borne encephalitis
      Authors: S Grygorczuk, M Parczewski, R ?wierzbi?s, P Czupryna, A Moniuszko, J Dunaj, M Kondrusik, S Pancewicz
      J Neuroinflammation, 2017;14(1):126.
      Species: Human
      Sample Type: Serum
    13. Elastin?derived peptides are involved in the processes of human temporomandibular disorder by inducing inflammatory responses in synovial cells
      Authors: K Kobayashi, R Jokaji, M Miyazawa-H, S Takatsuka, A Tanaka, K Ooi, H Nakamura, S Kawashiri
      Mol Med Rep, 2017;16(3):3147-3154.
      Species: Human
      Sample Type: Synovial Fluid
    14. Concurrent Aerobic and Resistance Training Has Anti-Inflammatory Effects and Increases Both Plasma and Leukocyte Levels of IGF-1 in Late Middle-Aged Type 2 Diabetic Patients
      Authors: G Annibalini, F Lucertini, D Agostini, L Vallorani, A Gioacchini, E Barbieri, M Guescini, L Casadei, A Passalia, M Del Sal, G Piccoli, M Andreani, A Federici, V Stocchi
      Oxid Med Cell Longev, 2017;2017(0):3937842.
      Species: Human
      Sample Type: Plasma
    15. Improvement in asymmetric dimethylarginine and oxidative stress in patients with limb salvage after autologous mononuclear stem cell application for critical limb ischemia
      Authors: J Madaric, M Valachovic, L Paulis, J Pribojova, R Mateova, K Sebekova, L Postulkova, T Madaricova, M Bucova, M Mistrik, I Vulev
      Stem Cell Res Ther, 2017;8(1):165.
      Species: Human
      Sample Type: Cell Culture Supernates
    16. Serum and peritoneal fluid concentrations of soluble human leukocyte antigen, tumor necrosis factor alpha and interleukin 10 in patients with selected ovarian pathologies
      Authors: O Sipak-Szmi, P W?odarski, E Ronin-Walk, A Niedzielsk, B Karakiewic, S S?uczanows, M Laszczy?sk, W Malinowski
      J Ovarian Res, 2017;10(1):25.
      Species: Human
      Sample Type: Serum
    17. Tumor necrosis factor alpha inhibitors have no effect on a human T-lymphotropic virus type-I (HTLV-I)-infected cell line from patients with HTLV-I-associated myelopathy
      Authors: S Fukui, H Nakamura, Y Takahashi, N Iwamoto, H Hasegawa, K Yanagihara, T Nakamura, A Okayama, A Kawakami
      BMC Immunol, 2017;18(1):7.
      Species: Human
      Sample Type: Cell Culture Supernates
    18. Polysialic acid blocks mononuclear phagocyte reactivity, inhibits complement activation, and protects from vascular damage in the retina
      EMBO Mol Med, 2016;0(0):.
      Species: Human
      Sample Type: Cell Culture Supernates
    19. Association of C1q/TNF-Related Protein-3 (CTRP3) and CTRP13 Serum Levels with Coronary Artery Disease in Subjects with and without Type 2 Diabetes Mellitus
      PLoS ONE, 2016;11(12):e0168773.
      Species: Human
      Sample Type: Serum
    20. Simple Plex() : A Novel Multi-Analyte, Automated Microfluidic Immunoassay Platform for the Detection of Human and Mouse Cytokines and Chemokines.
      Authors: Aldo P, Marusov G, Svancara D, David J, Mor G
      Am J Reprod Immunol, 2016;75(6):678-93.
      Species: Human
      Sample Type: Plasma
    21. Nuclear DNA damage-triggered NLRP3 inflammasome activation promotes UVB-induced inflammatory responses in human keratinocytes
      Authors: Tatsuya Hasegawa
      Biochem Biophys Res Commun, 2016;0(0):.
      Species: Human
      Sample Type: Cell Culture Supernates
    22. Cross-talk between intestinal epithelial cells and immune cells in inflammatory bowel disease
      Sci Rep, 2016;6(0):29783.
      Species: Human
      Sample Type: Cell Culture Supernates
    23. Innovative Flow Cytometry Allows Accurate Identification of Rare Circulating Cells Involved in Endothelial Dysfunction
      PLoS ONE, 2016;11(8):e0160153.
      Species: Human
      Sample Type: Plasma
    24. Cell surface-anchored syndecan-1 ameliorates intestinal inflammation and neutrophil transmigration in ulcerative colitis
      J Cell Mol Med, 2016;0(0):.
      Species: Human
      Sample Type: Serum
    25. A point mutation in AgrC determines cytotoxic or colonizing properties associated with phenotypic variants of ST22 MRSA strains
      Authors: S Mairpady S, N Siemens, IR Monk, DB Mohan, S Mukundan, KC Krishnan, S Prabhakara, J Snäll, A Kearns, F Vandenesch, M Svensson, M Kotb, B Gopal, G Arakere, A Norrby-Teg
      Sci Rep, 2016;6(0):31360.
      Species: Human
      Sample Type: Tissue Culture Supernates
    26. Association between Placental Lesions, Cytokines and Angiogenic Factors in Pregnant Women with Preeclampsia
      Authors: Ingrid C Weel
      PLoS ONE, 2016;11(6):e0157584.
      Species: Human
      Sample Type: Tissue Homogenates
    27. Modulation of Endothelial Inflammation by Low and High Magnitude Cyclic Stretch
      PLoS ONE, 2016;11(4):e0153387.
      Species: Human
      Sample Type: Cell Culture Supernates
    28. Unexpected Normal Colloid Osmotic Pressure in Clinical States with Low Serum Albumin
      PLoS ONE, 2016;11(7):e0159839.
      Species: Human
      Sample Type: Serum
    29. Subclinical Inflammation and Endothelial Dysfunction in Young Patients with Diabetes: A Study from United Arab Emirates
      PLoS ONE, 2016;11(7):e0159808.
      Species: Human
      Sample Type: Serum
    30. Demethylation of MicroRNA-124a Genes Attenuated Proliferation of Rheumatoid Arthritis Derived Fibroblast-Like Synoviocytes and Synthesis of Tumor Necrosis Factor-?
      PLoS ONE, 2016;11(11):e0164207.
      Species: Human
      Sample Type: Cell Culture Supernates
    31. Analysis of VEGFA Variants and Changes in VEGF Levels Underscores the Contribution of VEGF to Polycystic Ovary Syndrome
      PLoS ONE, 2016;11(11):e0165636.
      Species: Human
      Sample Type: Plasma
    32. The Association between Serum Cytokines and Damage to Large and Small Nerve Fibers in Diabetic Peripheral Neuropathy.
      Authors: Magrinelli F, Briani C, Romano M, Ruggero S, Toffanin E, Triolo G, Peter G, Praitano M, Lauriola M, Zanette G, Tamburin S
      J Diabetes Res, 2015;2015(0):547834.
      Species: Human
      Sample Type: Serum
    33. Phosphocholine-Modified Macromolecules and Canonical Nicotinic Agonists Inhibit ATP-Induced IL-1beta Release.
      Authors: Hecker A, Kullmar M, Wilker S, Richter K, Zakrzewicz A, Atanasova S, Mathes V, Timm T, Lerner S, Klein J, Kaufmann A, Bauer S, Padberg W, Kummer W, Janciauskiene S, Fronius M, Schweda E, Lochnit G, Grau V
      J Immunol, 2015;195(5):2325-34.
      Species: Human
      Sample Type: Cell Culture Supernates
    34. Blockade of PD-1 or p38 MAP kinase signaling enhances senescent human CD8(+) T-cell proliferation by distinct pathways.
      Authors: Henson S, Macaulay R, Riddell N, Nunn C, Akbar A
      Eur J Immunol, 2015;45(5):1441-51.
      Species: Human
      Sample Type: Cell Culture Supernates
    35. Dysregulated choline metabolism in T-cell lymphoma: role of choline kinase-alpha and therapeutic targeting.
      Authors: Xiong J, Bian J, Wang L, Zhou J, Wang Y, Zhao Y, Wu L, Hu J, Li B, Chen S, Yan C, Zhao W
      Blood Cancer J, 2015;5(0):287.
      Species: Human
      Sample Type: Cell Culture Supernates
    36. Serum levels of inflammatory markers in depressed elderly patients with diabetes and mild cognitive impairment.
      Authors: Gorska-Ciebiada M, Saryusz-Wolska M, Borkowska A, Ciebiada M, Loba J
      PLoS ONE, 2015;10(3):e0120433.
      Species: Human
      Sample Type: Serum
    37. Riboswitch-mediated Attenuation of Transgene Cytotoxicity Increases Adeno-associated Virus Vector Yields in HEK-293 Cells.
      Authors: Strobel B, Klauser B, Hartig J, Lamla T, Gantner F, Kreuz S
      Mol Ther, 2015;23(10):1582-91.
      Species: Human
      Sample Type: Cell Culture Supernates
    38. Dysregulated serum IL-23 and SIRT1 activity in peripheral blood mononuclear cells of patients with rheumatoid arthritis.
      Authors: Wendling D, Abbas W, Godfrin-Valnet M, Kumar A, Guillot X, Khan K, Vidon C, Coquard L, Toussirot E, Prati C, Herbein G
      PLoS ONE, 2015;10(3):e0119981.
      Species: Human
      Sample Type: Serum
    39. The Novel Receptor C5aR2 Is Required for C5a-Mediated Human Mast Cell Adhesion, Migration, and Proinflammatory Mediator Production.
      Authors: Pundir P, MacDonald C, Kulka M
      J Immunol, 2015;195(6):2774-87.
      Species: Human
      Sample Type: Cell Culture Supernates
    40. Sexual dimorphism in miR-210 expression and mitochondrial dysfunction in the placenta with maternal obesity.
      Authors: Muralimanoharan S, Guo C, Myatt L, Maloyan A
      Int J Obes (Lond), 2015;39(8):1274-81.
      Species: Human
      Sample Type: Tissue Homogenates
    41. A novel carboline derivative inhibits nitric oxide formation in macrophages independent of effects on tumor necrosis factor alpha and interleukin-1beta expression.
      Authors: Grodzki A, Poola B, Pasupuleti N, Nantz M, Lein P, Gorin F
      J Pharmacol Exp Ther, 2015;352(3):438-47.
      Species: Human
      Sample Type: Cell Culture Supernates
    42. The N terminus of type III secretion needle protein YscF from Yersinia pestis functions to modulate innate immune responses.
      Authors: Osei-Owusu P, Jessen Condry D, Toosky M, Roughead W, Bradley D, Nilles M
      Infect Immun, 2015;83(4):1507-22.
      Species: Human
      Sample Type: Cell Culture Supernates
    43. WNT5A transforms intestinal CD8alphaalpha(+) IELs into an unconventional phenotype with pro-inflammatory features.
      Authors: Zhao D, Xu A, Dai Z, Peng J, Zhu M, Shen J, Zheng Q, Ran Z
      BMC Gastroenterol, 2015;15(0):173.
      Species: Mouse
      Sample Type: Cell Culture Supernates
    44. Angiopoietin Like Protein 2 (ANGPTL2) Promotes Adipose Tissue Macrophage and T lymphocyte Accumulation and Leads to Insulin Resistance.
      Authors: Sasaki Y, Ohta M, Desai D, Figueiredo J, Whelan M, Sugano T, Yamabi M, Yano W, Faits T, Yabusaki K, Zhang H, Mlynarchik A, Inoue K, Mizuno K, Aikawa M
      PLoS ONE, 2015;10(7):e0131176.
      Species: Human
      Sample Type: Cell Culture Supernates
    45. The inflammation, vascular repair and injury responses to exercise in fit males with and without Type 1 diabetes: an observational study.
      Authors: West D, Campbell M, Gonzalez J, Walker M, Stevenson E, Ahmed F, Wijaya S, Shaw J, Weaver J
      Cardiovasc Diabetol, 2015;14(0):71.
      Species: Human
      Sample Type: Plasma
    46. Prostaglandin E2 Inhibits NLRP3 Inflammasome Activation through EP4 Receptor and Intracellular Cyclic AMP in Human Macrophages.
      Authors: Sokolowska M, Chen L, Liu Y, Martinez-Anton A, Qi H, Logun C, Alsaaty S, Park Y, Kastner D, Chae J, Shelhamer J
      J Immunol, 2015;194(11):5472-87.
      Species: Human
      Sample Type: Cell Culture Supernates
    47. Positive feedback between NF-kappaB and TNF-alpha promotes leukemia-initiating cell capacity.
      Authors: Kagoya Y, Yoshimi A, Kataoka K, Nakagawa M, Kumano K, Arai S, Kobayashi H, Saito T, Iwakura Y, Kurokawa M
      J Clin Invest, 2014;124(2):528-42.
      Species: Human
      Sample Type: Whole Cells
    48. Icariin ameliorates cigarette smoke induced inflammatory responses via suppression of NF-kappaB and modulation of GR in vivo and in vitro.
      Authors: Li L, Sun J, Xu C, Zhang H, Wu J, Liu B, Dong J
      PLoS ONE, 2014;9(8):e102345.
      Species: Human
      Sample Type: Cell Culture Supernates
    49. High activities of BACE1 in brains with mild cognitive impairment.
      Authors: Cheng X, He P, Lee T, Yao H, Li R, Shen Y
      Am J Pathol, 2014;184(1):141-7.
      Species: Human
      Sample Type: Tissue Homogenates
    50. Effects of pitavastatin versus atorvastatin on the peripheral endothelial progenitor cells and vascular endothelial growth factor in high-risk patients: a pilot prospective, double-blind, randomized study.
      Authors: Lin L, Huang C, Chen J, Wu T, Leu H, Huang P, Chang T, Lin S, Chen J
      Cardiovasc Diabetol, 2014;13(0):111.
      Species: Human
      Sample Type: Serum
    51. Bacteria induce prolonged PMN survival via a phosphatidylcholine-specific phospholipase C- and protein kinase C-dependent mechanism.
      Authors: Erttmann S, Gekara N, Fallman M
      PLoS ONE, 2014;9(1):e87859.
      Species: Human
      Sample Type: Cell Culture Supernates
    52. Vitamin D insufficiency and subclinical atherosclerosis in non-diabetic males living with HIV.
      Authors: Portilla J, Moreno-Perez O, Serna-Candel C, Escoin C, Alfayate R, Reus S, Merino E, Boix V, Giner L, Sanchez-Paya J, Pico A
      J Int AIDS Soc, 2014;17(0):18945.
      Species: Human
      Sample Type: Serum
    53. Systemic upregulation of PDGF-B in patients with neovascular AMD.
      Authors: Zehetner C, Kirchmair R, Neururer S, Kralinger M, Bechrakis N, Kieselbach G
      Invest Ophthalmol Vis Sci, 2014;55(1):337-44.
      Species: Human
      Sample Type: Plasma
    54. HIV-1 Nef impairs key functional activities in human macrophages through CD36 downregulation.
      Authors: Olivetta E, Tirelli V, Chiozzini C, Scazzocchio B, Romano I, Arenaccio C, Sanchez M
      PLoS ONE, 2014;9(4):e93699.
      Species: Human
      Sample Type: Cell Culture Supernates
    55. Oxidative and pro-inflammatory impact of regular and denicotinized cigarettes on blood brain barrier endothelial cells: is smoking reduced or nicotine-free products really safe?
      Authors: Naik, Pooja, Fofaria, Neel, Prasad, Shikha, Sajja, Ravi K, Weksler, Babette, Couraud, Pierre-O, Romero, Ignacio, Cucullo, Luca
      BMC Neurosci, 2014;15(0):51.
      Species: Human
      Sample Type: Cell Culture Supernates
    56. Mitochondrial hyperfusion promotes NF-kappaB activation via the mitochondrial E3 ligase MULAN.
      Authors: Zemirli N, Pourcelot M, Ambroise G, Hatchi E, Vazquez A, Arnoult D
      FEBS J, 2014;281(14):3095-112.
      Species: Human
      Sample Type: Cell Culture Supernates
    57. Directed evolution of an LBP/CD14 inhibitory peptide and its anti-endotoxin activity.
      Authors: Fang L, Xu Z, Wang G, Ji F, Mei C, Liu J, Wu G
      PLoS ONE, 2014;9(7):e101406.
      Species: Human
      Sample Type: Cell Culture Supernates
    58. The impact of concomitant pulmonary infection on immune dysregulation in Pneumocystis jirovecii pneumonia.
      Authors: Chou C, Lin F, Tsai H, Chang S
      BMC Pulm Med, 2014;14(0):182.
      Species: Human
      Sample Type: BALF
    59. Modelling Fanconi anemia pathogenesis and therapeutics using integration-free patient-derived iPSCs.
      Authors: Liu G, Suzuki K, Li M, Qu J, Montserrat N, Tarantino C, Gu Y, Yi F, Xu X, Zhang W, Ruiz S, Plongthongkum N, Zhang K, Masuda S, Nivet E, Tsunekawa Y, Soligalla R, Goebl A, Aizawa E, Kim N, Kim J, Dubova I, Li Y, Ren R, Benner C, del Sol A, Bueren J, Trujillo J, Surralles J, Cappelli E, Dufour C, Esteban C, Izpisua Belmonte J
      Nat Commun, 2014;5(0):4330.
      Species: Human
      Sample Type: Cell Culture Supernates
    60. Coinfection with human herpesvirus 8 is associated with persistent inflammation and immune activation in virologically suppressed HIV-infected patients.
      Authors: Masia M, Robledano C, Ortiz de la Tabla V, Antequera P, Lumbreras B, Hernandez I, Gutierrez F
      PLoS ONE, 2014;9(8):e105442.
      Species: Human
      Sample Type: Plasma
    61. Identification of a distinct glucocorticosteroid-insensitive pulmonary macrophage phenotype in patients with chronic obstructive pulmonary disease.
      Authors: Chana K, Fenwick P, Nicholson A, Barnes P, Donnelly L
      J Allergy Clin Immunol, 2014;133(1):207-16.e1-11.
      Species: Human
      Sample Type: Cell Culture Supernates
    62. Mucosal biomarkers of colorectal cancer risk do not increase at 6 months following sleeve gastrectomy, unlike gastric bypass.
      Authors: Kant P, Perry S, Dexter S, Race A, Loadman P, Hull M
      Obesity (Silver Spring), 2014;22(1):202-10.
      Species: Human
      Sample Type: Serum
    63. Circulating levels of tumor necrosis factor-alpha receptor 2 are increased in heart failure with preserved ejection fraction relative to heart failure with reduced ejection fraction: evidence for a divergence in pathophysiology.
      Authors: Putko B, Wang Z, Lo J, Anderson T, Becher H, Dyck J, Kassiri Z, Oudit G
      PLoS ONE, 2014;9(6):e99495.
      Species: Human
      Sample Type: Plasma
    64. Immune-inflammatory markers and arterial stiffness indexes in subjects with acute ischemic stroke with and without metabolic syndrome.
      Authors: Tuttolomondo A, Pecoraro R, Di Raimondo D, Di Sciacca R, Canino B, Arnao V, Butta C, Della Corte V, Maida C, Licata G, Pinto A
      Diabetol Metab Syndr, 2014;6(1):28.
      Species: Human
      Sample Type: Plasma
    65. Mycobacteria bypass mucosal NF-kB signalling to induce an epithelial anti-inflammatory IL-22 and IL-10 response.
      Authors: Lutay N, Hakansson G, Alaridah N, Hallgren O, Westergren-Thorsson G, Godaly G
      PLoS ONE, 2014;9(1):e86466.
      Species: Human
      Sample Type: Cell Culture Supernates
    66. The expression of cytokines and chemokines in the blood of patients with severe weight loss from anorexia nervosa: an exploratory study.
      Authors: Pisetsky D, Trace S, Brownley K, Hamer R, Zucker N, Roux-Lombard P, Dayer J, Bulik C
      Cytokine, 2014;69(1):110-5.
      Species: Human
      Sample Type: Cell Culture Supernates
    67. Restoration of CFTR function in patients with cystic fibrosis carrying the F508del-CFTR mutation.
      Authors: De Stefano D, Villella V, Esposito S, Tosco A, Sepe A, De Gregorio F, Salvadori L, Grassia R, Leone C, De Rosa G, Maiuri M, Pettoello-Mantovani M, Guido S, Bossi A, Zolin A, Venerando A, Pinna L, Mehta A, Bona G, Kroemer G, Maiuri L, Raia V
      Autophagy, 2014;10(11):2053-74.
      Species: Human
      Sample Type: Sputum
    68. Metabolic implications when employing heavy pre- and post-exercise rapid-acting insulin reductions to prevent hypoglycaemia in type 1 diabetes patients: a randomised clinical trial.
      Authors: Campbell M, Walker M, Trenell M, Luzio S, Dunseath G, Tuner D, Bracken R, Bain S, Russell M, Stevenson E, West D
      PLoS ONE, 2014;9(5):e97143.
      Species: Human
      Sample Type: Serum
    69. Factors associated with impairment of quadriceps muscle function in Chinese patients with chronic obstructive pulmonary disease.
      Authors: Ju C, Chen R
      PLoS ONE, 2014;9(2):e84167.
      Species: Human
      Sample Type: Serum
    70. Expression and functional characterization of NOD2 in decidual stromal cells isolated during the first trimester of pregnancy.
      Authors: Zhang Y, Chen H, Sun C, Wang H, Liu M, Li Y, Nie X, Du M, Li D, Zhang J
      PLoS ONE, 2014;9(6):e99612.
      Species: Human
      Sample Type: Cell Culture Supernates
    71. beta-glucan induces reactive oxygen species production in human neutrophils to improve the killing of Candida albicans and Candida glabrata isolates from vulvovaginal candidiasis.
      Authors: Bonfim-Mendonca P, Ratti B, Godoy J, Negri M, Lima N, Fiorini A, Hatanaka E, Consolaro M, de Oliveira Silva S, Svidzinski T
      PLoS ONE, 2014;9(9):e107805.
      Species: Human
      Sample Type: Cell Culture Supernates
    72. Tumor-associated macrophage-derived IL-6 and IL-8 enhance invasive activity of LoVo cells induced by PRL-3 in a KCNN4 channel-dependent manner.
      Authors: Xu H, Lai W, Zhang Y, Liu L, Luo X, Zeng Y, Wu H, Lan Q, Chu Z
      BMC Cancer, 2014;14(0):330.
      Species: Human
      Sample Type: Cell Culture Supernates
    73. Endocannabinoids affect innate immunity of Muller glia during HIV-1 Tat cytotoxicity.
      Authors: Krishnan G, Chatterjee N
      Mol Cell Neurosci, 2014;59(0):10-23.
      Species: Human
      Sample Type: Cell Culture Supernates
    74. Bile acids PKA-dependently induce a switch of the IL-10/IL-12 ratio and reduce proinflammatory capability of human macrophages.
      Authors: Haselow K, Bode J, Wammers M, Ehlting C, Keitel V, Kleinebrecht L, Schupp A, Haussinger D, Graf D
      J Leukoc Biol, 2013;94(6):1253-64.
      Species: Human
      Sample Type: Cell Culture Supernates
    75. Preeclamptic plasma induces transcription modifications involving the AP-1 transcriptional regulator JDP2 in endothelial cells.
      Authors: Calicchio R, Buffat C, Mathieu J, Ben Salem N, Mehats C, Jacques S, Hertig A, Berkane N, Grevoul-Fresquet J, Simeoni U, Peyssonnaux C, Gavard J, Vaiman D, Miralles F
      Am J Pathol, 2013;183(6):1993-2006.
      Species: Human
      Sample Type: Plasma
    76. Neutrophil microparticles modulate cytokine production by natural killer cells.
      Authors: Pliyev B, Kalintseva M, Abdulaeva S, Yarygin K, Savchenko V
      Cytokine, 2013;65(2):126-9.
      Species: Human
      Sample Type: Cell Culture Supernates
    77. Medium-chain fatty acid-sensing receptor, GPR84, is a proinflammatory receptor.
      Authors: Suzuki M, Takaishi S, Nagasaki M, Onozawa Y, Iino I, Maeda H, Komai T, Oda T
      J Biol Chem, 2013;288(15):10684-91.
      Species: Human
      Sample Type: Cell Culture Supernates
    78. Cleaved/associated TLR3 represents the primary form of the signaling receptor.
      Authors: Toscano F, Estornes Y, Virard F, Garcia-Cattaneo A, Pierrot A, Vanbervliet B, Bonnin M, Ciancanelli M, Zhang S, Funami K, Seya T, Matsumoto M, Pin J, Casanova J, Renno T, Lebecque S
      J Immunol, 2013;190(2):764-73.
      Species: Human
      Sample Type: Cell Culture Supernates
    79. Protein carbamylation predicts mortality in ESRD.
      Authors: Koeth R, Kalantar-Zadeh K, Wang Z, Fu X, Tang W, Hazen S
      , 2013;0(0):.
      Species: Human
      Sample Type: Serum
    80. Reference range and short- and long-term biological variation of interleukin (IL)-6, IL-17A and tissue necrosis factor-alpha using high sensitivity assays.
      Authors: Todd J, Simpson P, Estis J, Torres V, Wub A
      Cytokine, 2013;64(3):660-5.
      Species: Human
      Sample Type: Plasma
    81. CLEC5A is critical for dengue virus-induced inflammasome activation in human macrophages.
      Authors: Wu M, Chen S, Yang A, Lin W, Lin Y, Chen N, Tsai I, Li L, Hsieh S
      Blood, 2013;121(1):95-106.
      Species: Human
      Sample Type: Cell Culture Supernates
    82. Multiplexing immunoassays for cytokine detection in the serum of patients with rheumatoid arthritis: lack of sensitivity and interference by rheumatoid factor.
      Authors: Churchman SM, Geiler J, Parmar R, Horner EA, Church LD, Emery P, Buch MH, McDermott MF, Ponchel F
      Clin. Exp. Rheumatol., 2012;30(4):534-42.
      Species: Human
      Sample Type: Serum
    83. Mycobacterium bovis bacilli Calmette-Guerin regulates leukocyte recruitment by modulating alveolar inflammatory responses.
      Authors: Andersson M, Lutay N, Hallgren O, Westergren-Thorsson G, Svensson M, Godaly G
      Innate Immun, 2012;18(3):531-40.
      Species: Human
      Sample Type: Cell Culture Supernates
    84. Suppression of NF-kappaB Reduces Myocardial No-Reflow.
      Authors: Zeng M, Yan H, Chen Y, Zhao H, Lv Y, Liu C, Zhou P, Zhao B
      PLoS ONE, 2012;7(10):e47306.
      Species: Human
      Sample Type: Cell Culture Supernates
    85. Recombinant GPI-anchored TIMP-1 stimulates growth and migration of peritoneal mesothelial cells.
      Authors: Djafarzadeh R, Sauter M, Notohamiprodjo S, Noessner E, Goyal P, Siess W, Wornle M, Ribeiro A, Himmelein S, Sitter T, Nelson PJ
      PLoS ONE, 2012;7(4):e33963.
      Species: Human
      Sample Type: Cell Culture Supernates
    86. A novel small molecule, HK-156, inhibits lipopolysaccharide-induced activation of NF-kappaB signaling and improves survival in mouse models of sepsis.
      Acta Pharmacol. Sin., 2012;33(9):1204-16.
      Species: Human
      Sample Type: Cell Culture Supernates
    87. Attenuated, oncolytic, but not wild-type measles virus infection has pleiotropic effects on human neutrophil function.
      Authors: Zhang Y, Patel B, Dey A, Ghorani E, Rai L, Elham M, Castleton AZ, Fielding AK
      J. Immunol., 2012;188(3):1002-10.
      Species: Human
      Sample Type: Cell Culture Supernates
    88. A dynamic inflammatory cytokine network in the human ovarian cancer microenvironment.
      Authors: Kulbe H, Chakravarty P, Leinster DA, Charles KA, Kwong J, Thompson RG, Coward JI, Schioppa T, Robinson SC, Gallagher WM, Galletta L, Salako MA, Smyth JF, Hagemann T, Brennan DJ, Bowtell DD, Balkwill FR
      Cancer Res., 2012;72(1):66-75.
      Species: Human
      Sample Type: Cell Culture Supernates
    89. Small molecule inhibition of 6-phosphofructo-2-kinase suppresses t cell activation.
      J Transl Med, 2012;10(0):95.
      Species: Human
      Sample Type: Cell Culture Supernates
    90. Role of interleukin-32 in Helicobacter pylori-induced gastric inflammation.
      Authors: Sakitani K, Hirata Y, Hayakawa Y, Serizawa T, Nakata W, Takahashi R, Kinoshita H, Sakamoto K, Nakagawa H, Akanuma M, Yoshida H, Maeda S, Koike K
      Infect Immun, 2012;80(11):3795-803.
      Species: Human
      Sample Type: Cell Lysates
    91. High levels of beta-catenin signaling reduce osteogenic differentiation of stem cells in inflammatory microenvironments through inhibition of the noncanonical Wnt pathway.
      Authors: Liu N, Shi S, Deng M, Tang L, Zhang G, Liu N, Ding B, Liu W, Liu Y, Shi H, Liu L, Jin Y
      J. Bone Miner. Res., 2011;26(9):2082-95.
      Species: Human
      Sample Type: Cell Culture Supernates
    92. TWEAK Induces Apoptosis through a Death-signaling Complex Comprising Receptor-interacting Protein 1 (RIP1), Fas-associated Death Domain (FADD), and Caspase-8.
      Authors: Ikner A, Ashkenazi A
      J. Biol. Chem., 2011;286(24):21546-54.
      Species: Human
      Sample Type: Cell Culture Supernates
    93. Vitamin D(3) down-regulates proinflammatory cytokine response to Mycobacterium tuberculosis through pattern recognition receptors while inducing protective cathelicidin production.
      Authors: Khoo AL, Chai LY, Koenen HJ, Oosting M, Steinmeyer A, Zuegel U, Joosten I, Netea MG, van der Ven AJ
      Cytokine, 2011;55(2):294-300.
      Species: Human
      Sample Type: Cell Culture Supernates
    94. Kinetics of circulating Th17 cytokines and adipokines in psoriasis patients.
      Authors: Nakajima H, Nakajima K, Tarutani M, Morishige R, Sano S
      Arch. Dermatol. Res., 2011;303(6):451-5.
      Species: Human
      Sample Type: Serum
    95. HDAC inhibition by LBH589 affects the phenotype and function of human myeloid dendritic cells.
      Authors: Song W, Tai YT, Tian Z, Hideshima T, Chauhan D, Nanjappa P, Exley MA, Anderson KC, Munshi NC
      Leukemia, 2011;25(1):161-8.
      Species: Human
      Sample Type: Cell Culture Supernates
    96. Direct and indirect impairment of human dendritic cell function by virulent Francisella tularensis Schu S4.
      Authors: Chase JC, Celli J, Bosio CM
      Infect. Immun., 2009;77(1):180-95.
      Species: Human
      Sample Type: Cell Culture Supernates
    97. Immuno-inflammatory predictors of stroke at follow-up in patients with chronic non-valvular atrial fibrillation (NVAF).
      Authors: Pinto A, Tuttolomondo A, Casuccio A, Di Raimondo D, Di Sciacca R, Arnao V, Licata G
      Clin. Sci., 2009;116(10):781-9.
      Species: Human
      Sample Type: Plasma
    98. In vivo regulation of interleukin 1beta in patients with cryopyrin-associated periodic syndromes.
      Authors: Lachmann HJ, Lowe P, Felix SD, Rordorf C, Leslie K, Madhoo S, Wittkowski H, Bek S, Hartmann N, Bosset S, Hawkins PN, Jung T
      J. Exp. Med., 2009;206(5):1029-36.
      Species: Human
      Sample Type: Plasma
    99. Escherichia coli type 1 pili trigger late IL-8 production by neutrophil-like differentiated PLB-985 cells through a Src family kinase- and MAPK-dependent mechanism.
      Authors: Semiramoth N, Gleizes A, Turbica I, Sandre C, Gorges R, Kansau I, Servin A, Chollet-Martin S
      J. Leukoc. Biol., 2009;85(2):310-21.
      Species: Human
      Sample Type: Cell Culture Supernates
    100. Immunologic analysis of HIV-uninfected Taiwanese children with BCG-induced disease.
      Authors: Lee WI, Liang FC, Huang JL, Jaing TH, Wang CH, Lin TY, Huang YC, Huang WL, Jou R, Hsieh MY, Chia JH, Wu TL
      J. Clin. Immunol., 2009;29(3):319-29.
      Species: Human
      Sample Type: Cell Culture Supernates
    101. Neisseria gonorrhoeae activates the proteinase cathepsin B to mediate the signaling activities of the NLRP3 and ASC-containing inflammasome.
      Authors: Duncan JA, Gao X, Huang MT, O'Connor BP, Thomas CE, Willingham SB, Bergstralh DT, Jarvis GA, Sparling PF, Ting JP
      J. Immunol., 2009;182(10):6460-9.
      Species: Human
      Sample Type: Cell Culture Supernates
    102. Immuno-inflammatory and thrombotic/fibrinolytic variables associated with acute ischemic stroke diagnosis.
      Authors: Tuttolomondo A, Pinto A, Corrao S, Di Raimondo D, Fernandez P, Di Sciacca R, Arnao V, Licata G
      Atherosclerosis, 2009;203(2):503-8.
      Species: Human
      Sample Type: Plasma
    103. Cytokine secretion by human mesenchymal stem cells cocultured with damaged corneal epithelial cells.
      Authors: Oh JY, Kim MK, Shin MS, Wee WR, Lee JH
      Cytokine, 2009;46(1):100-3.
      Species: Human
      Sample Type: Cell Culture Supernates
    104. Inflammatory interaction between LIGHT and proteinase-activated receptor-2 in endothelial cells: potential role in atherogenesis.
      Authors: Sandberg WJ, Halvorsen B, Yndestad A, Smith C, Otterdal K, Brosstad FR, Froland SS, Olofsson PS, Damas JK, Gullestad L, Hansson GK, Oie E, Aukrust P
      Circ. Res., 2009;104(1):60-8.
      Species: Human
      Sample Type: Cell Culture Supernates
    105. The novel lipopolysaccharide-binding protein CRISPLD2 is a critical serum protein to regulate endotoxin function.
      Authors: Wang ZQ, Xing WM, Fan HH, Wang KS, Zhang HK, Wang QW, Qi J, Yang HM, Yang J, Ren YN, Cui SJ, Zhang X, Liu F, Lin DH, Wang WH, Hoffmann MK, Han ZG
      J. Immunol., 2009;183(10):6646-56.
      Species: Human
      Sample Type: Cell Culture Supernates
    106. KiSS1 metastasis suppressor gene product induces suppression of tyrosine kinase receptor signaling to Akt, tumor necrosis factor family ligand expression, and apoptosis.
      Authors: Navenot JM, Fujii N, Peiper SC
      Mol. Pharmacol., 2009;75(5):1074-83.
      Species: Human
      Sample Type: Cell Culture Supernates
    107. IL-17 in atopic eczema: linking allergen-specific adaptive and microbial-triggered innate immune response.
      Authors: Eyerich K, Pennino D, Scarponi C, Foerster S, Nasorri F, Behrendt H, Ring J, Traidl-Hoffmann C, Albanesi C, Cavani A
      J. Allergy Clin. Immunol., 2009;123(1):59-66.e4.
      Species: Human
      Sample Type: Cell Culture Supernates
    108. Decoy receptor 3 levels in peripheral blood predict outcomes of acute respiratory distress syndrome.
      Authors: Chen CY, Yang KY, Chen MY, Chen HY, Lin MT, Lee YC, Perng RP, Hsieh SL, Yang PC, Chou TY
      Am. J. Respir. Crit. Care Med., 2009;180(8):751-60.
      Species: Human
      Sample Type: Plasma
    109. Interleukin-32 promotes osteoclast differentiation but not osteoclast activation.
      Authors: Mabilleau G, Sabokbar A
      PLoS ONE, 2009;4(1):e4173.
      Species: Human
      Sample Type: Cell Culture Supernates
    110. Distinct subsets of human invariant NKT cells differentially regulate T helper responses via dendritic cells.
      Authors: Liu TY, Uemura Y, Suzuki M, Narita Y, Hirata S, Ohyama H, Ishihara O, Matsushita S
      Eur. J. Immunol., 2008;38(4):1012-23.
      Species: Human
      Sample Type: Cell Culture Supernates
    111. Assessment of cervicovaginal cytokine levels following exposure to microbicide Nisin gel in rabbits.
      Authors: Aranha CC, Gupta SM, Reddy KV
      Cytokine, 2008;43(1):63-70.
      Species: Rabbit
      Sample Type: Vaginal Lavage
    112. Mycobacterium bovis Bacillus Calmette-Guerin suppresses inflammatory Th2 responses by inducing functional alteration of TSLP-activated dendritic cells.
      Authors: Yokoi T, Amakawa R, Tanijiri T, Sugimoto H, Torii Y, Amuro H, Son Y, Tajima K, Liu YJ, Ito T, Fukuhara S
      Int. Immunol., 2008;20(10):1321-9.
      Species: Human
      Sample Type: Cell Culture Supernates
    113. Aspergillus fumigatus stimulates leukocyte adhesion molecules and cytokine production by endothelial cells in vitro and during invasive pulmonary disease.
      Authors: Chiang LY, Sheppard DC, Gravelat FN, Patterson TF, Filler SG
      Infect. Immun., 2008;76(8):3429-38.
      Species: Human
      Sample Type: Cell Culture Supernates
    114. Selective inhibition of proprotein convertases represses the metastatic potential of human colorectal tumor cells.
      Authors: Scamuffa N, Siegfried G, Bontemps Y, Ma L, Basak A, Cherel G, Calvo F, Seidah NG, Khatib AM
      J. Clin. Invest., 2008;118(1):352-63.
      Species: Human
      Sample Type: Cell Culture Supernates
    115. NF-kappaB-dependent cytokines in saliva and serum from patients with oral lichen planus: a study in an ethnic Chinese population.
      Authors: Zhang Y, Lin M, Zhang S, Wang Z, Jiang L, Shen J, Bai J, Gao F, Zhou M, Chen Q
      Cytokine, 2008;41(2):144-9.
      Species: Human
      Sample Type: Serum
    116. MMP-12 induces IL-8/CXCL8 secretion through EGFR and ERK1/2 activation in epithelial cells.
      Authors: Le Quement C, Guenon I, Gillon JY, Lagente V, Boichot E
      Am. J. Physiol. Lung Cell Mol. Physiol., 2008;294(6):L1076-84.
      Species: Human
      Sample Type: Cell Culture Supernates
    117. In vivo transmigrated monocytes from patients with stable coronary artery disease have a reduced expression of CD11b.
      Authors: Paulsson JM, Dadfar E, Held C, Jacobson SH, Lundahl J
      Clin. Exp. Immunol., 2008;153(2):196-204.
      Species: Human
      Sample Type: Blister Fluid
    118. Cellular trafficking of lipoteichoic acid and Toll-like receptor 2 in relation to signaling: role of CD14 and CD36.
      Authors: Nilsen NJ, Deininger S, Nonstad U, Skjeldal F, Husebye H, Rodionov D, von Aulock S, Hartung T, Lien E, Bakke O, Espevik T
      J. Leukoc. Biol., 2008;84(1):280-91.
      Species: Human
      Sample Type: Cell Culture Supernates
    119. Infiltrated neutrophils acquire novel chemokine receptor expression and chemokine responsiveness in chronic inflammatory lung diseases.
      Authors: Hartl D, Krauss-Etschmann S, Koller B, Hordijk PL, Kuijpers TW, Hoffmann F, Hector A, Eber E, Marcos V, Bittmann I, Eickelberg O, Griese M, Roos D
      J. Immunol., 2008;181(11):8053-67.
      Species: Human
      Sample Type: BALF
    120. High levels and inflammatory effects of soluble CXC ligand 16 (CXCL16) in coronary artery disease: down-regulatory effects of statins.
      Authors: Smith C, Halvorsen B, Otterdal K, Waehre T, Yndestad A, Fevang B, Sandberg WJ, Breland UM, Froland SS, Oie E, Gullestad L, Damas JK, Aukrust P
      Cardiovasc. Res., 2008;79(1):195-203.
      Species: Human
      Sample Type: Cell Culture Supernates
    121. Synergistic interactions between interferon-gamma and TRAIL modulate c-FLIP in endothelial cells, mediating their lineage-specific sensitivity to thrombotic thrombocytopenic purpura plasma-associated apoptosis.
      Authors: Stefanescu R, Bassett D, Modarresi R, Santiago F, Fakruddin M, Laurence J
      Blood, 2008;112(2):340-9.
      Species: Human
      Sample Type: Plasma
    122. Neurotrophins modulate monocyte chemotaxis without affecting macrophage function.
      Authors: Samah B, Porcheray F, Gras G
      Clin. Exp. Immunol., 2008;151(3):476-86.
      Species: Human
      Sample Type: Cell Culture Supernates
    123. Dysregulation of IL-32 in myelodysplastic syndrome and chronic myelomonocytic leukemia modulates apoptosis and impairs NK function.
      Authors: Marcondes AM, Mhyre AJ, Stirewalt DL, Kim SH, Dinarello CA, Deeg HJ
      Proc. Natl. Acad. Sci. U.S.A., 2008;105(8):2865-70.
      Species: Human
      Sample Type: Bone Marrow Plasma
    124. Impairment of human NK cell cytotoxic activity and cytokine release by cigarette smoke.
      Authors: Mian MF, Lauzon NM, Stampfli MR, Mossman KL, Ashkar AA
      J. Leukoc. Biol., 2007;83(3):774-84.
      Species: Human
      Sample Type: Cell Culture Supernates
    125. C-reactive protein induces endothelial cell apoptosis and matrix metalloproteinase-9 production in human mononuclear cells: Implications for the destabilization of atherosclerotic plaque.
      Authors: Nabata A, Kuroki M, Ueba H, Hashimoto S, Umemoto T, Wada H, Yasu T, Saito M, Momomura S, Kawakami M
      Atherosclerosis, 2007;196(1):129-35.
      Species: Human
      Sample Type: Cell Culture Supernates
    126. Translocation of bacterial DNA from Gram-positive microorganisms is associated with a species-specific inflammatory response in serum and ascitic fluid of patients with cirrhosis.
      Authors: Frances R, Gonzalez-Navajas JM, Zapater P, Munoz C, Cano R, Pascual S, Santana F, Marquez D, Perez-Mateo M, Such J
      Clin. Exp. Immunol., 2007;150(2):230-7.
      Species: Human
      Sample Type: Serum
    127. Panel of markers can accurately predict endometriosis in a subset of patients.
      Authors: Seeber B, Sammel MD, Fan X, Gerton GL, Shaunik A, Chittams J, Barnhart KT
      Fertil. Steril., 2007;89(5):1073-81.
      Species: Human
      Sample Type: Serum
    128. Nitrosative stress predicts the presence and severity of nonalcoholic fatty liver at different stages of the development of insulin resistance and metabolic syndrome: possible role of vitamin A intake.
      Authors: Musso G, Gambino R, De Michieli F, Biroli G, Premoli A, Pagano G, Bo S, Durazzo M, Cassader M
      Am. J. Clin. Nutr., 2007;86(3):661-71.
      Species: Human
      Sample Type: Serum
    129. Angiopoietin-2 is increased in severe sepsis: correlation with inflammatory mediators.
      Authors: Orfanos SE, Kotanidou A, Glynos C, Athanasiou C, Tsigkos S, Dimopoulou I, Sotiropoulou C, Zakynthinos S, Armaganidis A, Papapetropoulos A, Roussos C
      Crit. Care Med., 2007;35(1):199-206.
      Species: Human
      Sample Type: Serum
    130. Peroxisome proliferator-activated receptor-gamma agonists inhibit respiratory syncytial virus-induced expression of intercellular adhesion molecule-1 in human lung epithelial cells.
      Authors: Arnold R, Neumann M, Konig W
      Immunology, 2007;121(1):71-81.
      Species: Human
      Sample Type: Cell Culture Supernates
    131. The levels of steroid hormones and cytokines in individual follicles are not associated with the fertilization outcome after intracytoplasmic sperm injection.
      Authors: Asimakopoulos B, Abu-Hassan D, Metzen E, Al-Hasani S, Diedrich K, Nikolettos N
      Fertil. Steril., 2007;90(1):60-4.
      Species: Human
      Sample Type: Follicular Fluid
    132. Tumor necrosis factor alpha as a new target for renal cell carcinoma: two sequential phase II trials of infliximab at standard and high dose.
      Authors: Harrison ML, Obermueller E, Maisey NR, Hoare S, Edmonds K, Li NF, Chao D, Hall K, Lee C, Timotheadou E, Charles K, Ahern R, King DM, Eisen T, Corringham R, DeWitte M, Balkwill F, Gore M
      J. Clin. Oncol., 2007;25(29):4542-9.
      Species: Human
      Sample Type: Plasma
    133. Placental growth factor down-regulates type 1 T helper immune response by modulating the function of dendritic cells.
      Authors: Lin YL, Liang YC, Chiang BL
      J. Leukoc. Biol., 2007;82(6):1473-80.
      Species: Human
      Sample Type: Cell Culture Supernates
    134. Microparticles of human atherosclerotic plaques enhance the shedding of the tumor necrosis factor-alpha converting enzyme/ADAM17 substrates, tumor necrosis factor and tumor necrosis factor receptor-1.
      Authors: Canault M, Leroyer AS, Peiretti F, Leseche G, Tedgui A, Bonardo B, Alessi MC, Boulanger CM, Nalbone G
      Am. J. Pathol., 2007;171(5):1713-23.
      Species: Human
      Sample Type: Cell Culture Supernates
    135. Advanced glycation end products increases matrix metalloproteinase-1, -3, and -13, and TNF-alpha in human osteoarthritic chondrocytes.
      Authors: Nah SS, Choi IY, Yoo B, Kim YG, Moon HB, Lee CK
      FEBS Lett., 2007;581(9):1928-32.
      Species: Human
      Sample Type: Cell Culture Supernates
    136. Effects of darbepoetin-alpha on plasma pro-inflammatory cytokines, anti-inflammatory cytokine interleukin-10 and soluble Fas/Fas ligand system in anemic patients with chronic heart failure.
      Authors: Kourea K, Parissis JT, Farmakis D, Panou F, Paraskevaidis I, Venetsanou K, Filippatos G, Kremastinos DT
      Atherosclerosis, 2007;199(1):215-21.
      Species: Human
      Sample Type: Plasma
    137. Newly recruited human monocytes have a preserved responsiveness towards bacterial peptides in terms of CD11b up-regulation and intracellular hydrogen peroxide production.
      Authors: Dadfar E, Jacobson SH, Lundahl J
      Clin. Exp. Immunol., 2007;148(3):573-82.
      Species: Human
      Sample Type: Serum
    138. Glucocorticoid-induced tumour necrosis factor receptor-related protein-mediated macrophage stimulation may induce cellular adhesion and cytokine expression in rheumatoid arthritis.
      Authors: Bae E, Kim WJ, Kang YM, Suk K, Koh EM, Cha HS, Ahn KS, Huh TL, Lee WH
      Clin. Exp. Immunol., 2007;148(3):410-8.
      Species: Human
      Sample Type: Cell Culture Supernates
    139. Muscle atrophy and hypertrophy signaling in patients with chronic obstructive pulmonary disease.
      Authors: Doucet M, Russell AP, Leger B, Debigare R, Joanisse DR, Caron MA, LeBlanc P, Maltais F
      Am. J. Respir. Crit. Care Med., 2007;176(3):261-9.
      Species: Human
      Sample Type: Plasma
    140. In vitro and in vivo effects of salbutamol on neutrophil function in acute lung injury.
      Authors: Perkins GD, Nathani N, McAuley DF, Gao F, Thickett DR
      Thorax, 2007;62(1):36-42.
      Species: Human
      Sample Type: BALF
    141. TREM-1 expression in tumor-associated macrophages and clinical outcome in lung cancer.
      Authors: Ho CC, Liao WY, Wang CY, Lu YH, Huang HY, Chen HY, Chan WK, Chen HW, Yang PC
      Am. J. Respir. Crit. Care Med., 2007;177(7):763-70.
      Species: Human
      Sample Type: Whole Cells
    142. Follistatin-like protein-1 is a novel proinflammatory molecule.
      Authors: Miyamae T, Marinov AD, Sowders D, Wilson DC, Devlin J, Boudreau R, Robbins P, Hirsch R
      J. Immunol., 2006;177(7):4758-62.
      Species: Human
      Sample Type: Cell Culture Supernates
    143. Induction of dendritic cell maturation by pertussis toxin and its B subunit differentially initiate Toll-like receptor 4-dependent signal transduction pathways.
      Authors: Wang ZY, Yang D, Chen Q, Leifer CA, Segal DM, Su SB, Caspi RR, Howard ZO, Oppenheim JJ
      Exp. Hematol., 2006;34(8):1115-24.
      Species: Human
      Sample Type: Cell Culture Supernates
    144. The acylation state of mycobacterial lipomannans modulates innate immunity response through toll-like receptor 2.
      Authors: Gilleron M, Nigou J, Nicolle D, Quesniaux V, Puzo G
      Chem. Biol., 2006;13(1):39-47.
      Species: Human
      Sample Type: Cell Culture Supernates
    145. Glycerol monolaurate inhibits the effects of Gram-positive select agents on eukaryotic cells.
      Authors: Peterson ML, Schlievert PM
      Biochemistry, 2006;45(7):2387-97.
      Species: Human
      Sample Type: Cell Culture Supernates
    146. Proinflammatory cytokines, insulin resistance, and insulin secretion in chronic hepatitis C patients: A case-control study.
      Authors: Lecube A, Hernandez C, Genesca J, Simo R
      Diabetes Care, 2006;29(5):1096-101.
      Species: Human
      Sample Type: Serum
    147. The shedding activity of ADAM17 is sequestered in lipid rafts.
      Authors: Tellier E, Rebsomen L
      Exp. Cell Res., 2006;312(20):3969-80.
      Species: Human
      Sample Type: Cell Lysates
    148. IL-23 is increased in dendritic cells in multiple sclerosis and down-regulation of IL-23 by antisense oligos increases dendritic cell IL-10 production.
      Authors: Vaknin-Dembinsky A, Balashov K, Weiner HL
      J. Immunol., 2006;176(12):7768-74.
      Species: Human
      Sample Type: Cell Culture Supernates
    149. Decreased plasma CXCL16/SR-PSOX concentration is associated with coronary artery disease.
      Authors: Sheikine Y, Bang CS, Nilsson L, Samnegard A, Hamsten A, Jonasson L, Eriksson P, Sirsjo A
      Atherosclerosis, 2006;188(2):462-6.
      Species: Human
      Sample Type: Serum
    150. Kinin receptor expression during Staphylococcus aureus infection.
      Authors: Bengtson SH, Phagoo SB, Norrby-Teglund A, Pahlman L, Morgelin M, Zuraw BL, Leeb-Lundberg LM, Herwald H
      Blood, 2006;108(6):2055-63.
      Species: Human
      Sample Type: Cell Culture Supernates
    151. Modulation of cytokine secretion by pentacyclic triterpenes from olive pomace oil in human mononuclear cells.
      Authors: Marquez-Martin A, De La Puerta R, Fernandez-Arche A, Ruiz-Gutierrez V, Yaqoob P
      Cytokine, 2006;36(5):211-7.
      Species: Human
      Sample Type: Cell Culture Supernates
    152. Th2 cytokine response in Major Depressive Disorder patients before treatment.
      Authors: Pavon L, Kiryushko D, Novitskaya V, Sandoval-Lopez G, Eugenia Hernandez M, Soroka V, Klingelhofer J, Loria F, Estrada I, Lukanidin E, Berezin V, Perez M, Moreno J, Bock E, Avila U, Leff P, Anton B, Heinze G
      J. Neuroimmunol., 2006;172(1):156-65.
      Species: Human
      Sample Type: Serum
    153. No difference in the effects of clopidogrel and aspirin on inflammatory markers in patients with coronary heart disease.
      Authors: Solheim S, Pettersen AA, Arnesen H, Seljeflot I
      Thromb. Haemost., 2006;96(5):660-4.
      Species: Human
      Sample Type: Serum
    154. Human liver sinusoidal endothelial cells induce apoptosis in activated T cells: a role in tolerance induction.
      Authors: Karrar A, Broome U, Uzunel M, Qureshi AR, Sumitran-Holgersson S
      Gut, 2006;56(2):243-52.
      Species: Human
      Sample Type: Cell Culture Supernates
    155. The potential of adiponectin in driving arthritis.
      Authors: Ehling A, Schaffler A, Herfarth H, Tarner IH, Anders S, Distler O, Paul G, Distler J, Gay S, Scholmerich J, Neumann E, Muller-Ladner U
      J. Immunol., 2006;176(7):4468-78.
      Species: Human
      Sample Type: Cell Culture Supernates
    156. Human intestinal intraepithelial lymphocytes keep TNF alpha levels low by cell uptake and feedback inhibition of transcription.
      Authors: Ebert EC, Mehta V
      Cell. Immunol., 2006;241(1):7-13.
      Species: Human
      Sample Type: Cell Culture Supernates
    157. Celecoxib up-regulates the expression of the zeta chain of T cell receptor complex in tumor-infiltrating lymphocytes in human cervical cancer.
      Authors: Ferrandina G, Ranelletti FO, Legge F, Salutari V, Martinelli E, Fattorossi A, Lorusso D, Zannoni G, Vellone V, Paglia A, Scambia G
      Clin. Cancer Res., 2006;12(7):2055-60.
      Species: Human
      Sample Type: Serum
    158. Erythropoiesis abnormalities contribute to early-onset anemia in patients with septic shock.
      Authors: Claessens YE, Fontenay M, Pene F, Chiche JD, Guesnu M, Hababou C, Casadevall N, Dhainaut JF, Mira JP, Cariou A
      Am. J. Respir. Crit. Care Med., 2006;174(1):51-7.
      Species: Human
      Sample Type: Plasma
    159. Non-esterified fatty acid concentrations are independently associated with hepatic steatosis in obese subjects.
      Authors: Holt HB, Wild SH, Wood PJ, Zhang J, Darekar AA, Dewbury K, Poole RB, Holt RI, Phillips DI, Byrne CD
      Diabetologia, 2006;49(1):141-8.
      Species: Human
      Sample Type: Serum
    160. Influence of eotaxin 67G>A polymorphism on plasma eotaxin concentrations in myocardial infarction survivors and healthy controls.
      Authors: Sheikine Y, Olsen B, Gharizadeh B, Jatta K, Tornvall P, Ghaderi M
      Atherosclerosis, 2006;189(2):458-63.
      Species: Human
      Sample Type: Serum
    161. Inhibitory effects of micronized fenofibrate on carotid atherosclerosis in patients with essential hypertension.
      Authors: Zhu S, Su G, Meng QH
      Clin. Chem., 2006;52(11):2036-42.
      Species: Human
      Sample Type: Serum
    162. Adiponectin and other adipocytokines as predictors of markers of triglyceride-rich lipoprotein metabolism.
      Authors: Chan DC, Watts GF, Ng TW, Uchida Y, Sakai N, Yamashita S, Barrett PH
      Clin. Chem., 2005;51(3):578-85.
      Species: Human
      Sample Type: Plasma
    163. Regulation of peritoneal and systemic neutrophil-derived tumor necrosis factor-alpha release in patients with severe peritonitis: role of tumor necrosis factor-alpha converting enzyme cleavage.
      Authors: Kermarrec N, Selloum S, Plantefeve G, Chosidow D, Paoletti X, Lopez A, Mantz J, Desmonts JM, Gougerot-Pocidalo MA, Chollet-Martin S
      Crit. Care Med., 2005;33(6):1359-64.
      Species: Human
      Sample Type: Cell Culture Supernates
    164. Circulating and synovial levels of IGF-I, cytokines, physical function and anthropometry differ in women awaiting total knee arthroplasty when compared to men.
      Authors: Pagura SM, Thomas SG, Woodhouse LJ, Ezzat S, Marks P
      J. Orthop. Res., 2005;23(2):397-405.
      Species: Human
      Sample Type: Synovial Fluid
    165. Relationship between cytokines and the embryotoxicity of hydrosalpingeal fluid.
      Authors: Bedaiwy MA, Falcone T, Goldberg JM, Attaran M, Sharma R, Miller K, Nelson DR, Agarwal A
      J. Assist. Reprod. Genet., 2005;22(4):161-5.
      Species: Human
      Sample Type: Hypersalpingeal Fluid (HSF)
    166. Growth hormone-induced reduction of soluble apoptosis mediators is associated with reverse cardiac remodelling and improvement of exercise capacity in patients with idiopathic dilated cardiomyopathy.
      Authors: Parissis JT, Adamopoulos S, Karatzas D, Paraskevaidis J, Livanis E, Kremastinos D
      Eur J Cardiovasc Prev Rehabil, 2005;12(2):164-8.
      Species: Human
      Sample Type: Plasma
    167. Increased expression of p38 MAPK in human bronchial epithelium after lipopolysaccharide exposure.
      Authors: Roos-Engstrand E, Wallin A, Bucht A, Pourazar J, Sandstrom T, Blomberg A
      Eur. Respir. J., 2005;25(5):797-803.
    168. Markers of immune activation and viral load in HIV-associated sensory neuropathy.
      Authors: Schifitto G, McDermott MP, McArthur JC, Marder K, Sacktor N, McClernon DR, Conant K, Cohen B, Epstein LG, Kieburtz K, Kieburtz K
      Neurology, 2005;64(5):842-8.
      Species: Human
      Sample Type: Plasma
    169. Proinflammatory mediators elicit secretion of the intracellular B-lymphocyte stimulator pool (BLyS) that is stored in activated neutrophils: implications for inflammatory diseases.
      Authors: Scapini P, Carletto A, Nardelli B, Calzetti F, Roschke V, Merigo F, Tamassia N, Pieropan S, Biasi D, Sbarbati A, Sozzani S, Bambara L, Cassatella MA
      Blood, 2005;105(2):830-7.
      Species: Human
      Sample Type: Cell Lysates
    170. Aseptic peritonitis due to peptidoglycan contamination of pharmacopoeia standard dialysis solution.
      Authors: Martis L, Patel M, Giertych J, Mongoven J, Taminne M, Perrier MA, Mendoza O, Goud N, Costigan A, Denjoy N, Verger C, Owen WF
      Lancet, 2005;365(9459):588-94.
      Species: Human
      Sample Type: Complex Sample Type
    171. Normal nasal mucociliary clearance in CF children: evidence against a CFTR-related defect.
      Authors: McShane D, Davies JC, Wodehouse T, Bush A, Geddes D, Alton EW
      Eur. Respir. J., 2004;24(1):95-100.
      Species: Human
      Sample Type: Nasal Lavage
    172. Amniotic fluid tumor necrosis factor-alpha is a marker for the prediction of early-onset neonatal sepsis in preterm labor.
      Authors: Park KH, Yoon BH, Shim SS, Jun JK, Syn HC
      Gynecol. Obstet. Invest., 2004;58(2):84-90.
      Species: Human
      Sample Type: Amniotic Fluid
    173. Inflammation and nitric oxide production in skeletal muscle of type 2 diabetic patients.
      Authors: Torres SH, De Sanctis JB, de L Briceno M, Hernandez N, Finol HJ
      J. Endocrinol., 2004;181(3):419-27.
      Species: Human
      Sample Type: Tissue Homogenates
    174. Inflammatory cytokine concentrations are elevated in seminal plasma of men with spinal cord injuries.
      Authors: Basu S, Aballa TC, Ferrell SM, Lynne CM, Brackett NL
      J. Androl., 2004;25(2):250-4.
      Species: Human
      Sample Type: Seminal Plasma
    175. Specific recognition and killing of glioblastoma multiforme by interleukin 13-zetakine redirected cytolytic T cells.
      Authors: Kahlon KS, Brown C, Cooper LJ, Raubitschek A, Forman SJ, Jensen MC
      Cancer Res., 2004;64(24):9160-6.
      Species: Human
      Sample Type: Cell Culture Supernates
    176. Role of transforming growth factor-beta in breast milk for initiation of IgA production in newborn infants.
      Authors: Ogawa J, Sasahara A, Yoshida T, Sira MM, Futatani T, Kanegane H, Miyawaki T
      Early Hum. Dev., 2004;77(1):67-75.
      Species: Human
      Sample Type: Colostrum
    177. Influence of eicosapentaenoic acid, an omega-3 fatty acid, on ultraviolet-B generation of prostaglandin-E2 and proinflammatory cytokines interleukin-1 beta, tumor necrosis factor-alpha, interleukin-6 and interleukin-8 in human skin in vivo.
      Authors: Shahbakhti H, Watson RE, Azurdia RM, Ferreira CZ, Garmyn M, Rhodes LE
      Photochem. Photobiol., 2004;80(2):231-5.
      Species: Human
      Sample Type: Plasma
    178. Effects of antiasthmatic agents on the functions of peripheral blood monocyte-derived dendritic cells from atopic patients.
      Authors: Saeki S, Matsuse H, Kondo Y, Machida I, Kawano T, Tomari S, Obase Y, Fukushima C, Kohno S
      J. Allergy Clin. Immunol., 2004;114(3):538-44.
      Species: Human
      Sample Type: Cell Culture Supernates
    179. Changes in CSF S100B and cytokine concentrations in early-phase severe traumatic brain injury.
      Authors: Hayakata T, Shiozaki T, Tasaki O, Ikegawa H, Inoue Y, Toshiyuki F, Hosotubo H, Kieko F, Yamashita T, Tanaka H, Shimazu T, Sugimoto H
      Shock, 2004;22(2):102-7.
      Species: Human
      Sample Type: Serum
    180. Pro- and anti-inflammatory responses in respiratory syncytial virus bronchiolitis.
      Authors: McNamara PS, Flanagan BF, Selby AM, Hart CA, Smyth RL
      Eur. Respir. J., 2004;23(1):106-12.
      Species: Human
      Sample Type: BALF
    181. Presence of dendritic cells, MCP-1, and activated microglia/macrophages in amyotrophic lateral sclerosis spinal cord tissue.
      Authors: Henkel JS, Engelhardt JI, Siklos L, Simpson EP, Kim SH, Pan T, Goodman JC, Siddique T, Beers DR, Appel SH
      Ann. Neurol., 2004;55(2):221-35.
      Species: Human
      Sample Type: CSF
    182. Antifungal immune reactivity in nasal polyposis.
      Authors: Pitzurra L, Bellocchio S, Nocentini A, Bonifazi P, Scardazza R, Gallucci L, Stracci F, Simoncelli C, Bistoni F, Romani L
      Infect. Immun., 2004;72(12):7275-81.
      Species: Human
      Sample Type: Nasal Lavage
    183. Guiding the vaginal microbicide trials with biomarkers of inflammation.
      Authors: Fichorova RN
      J. Acquir. Immune Defic. Syndr., 2004;37(0):S184-93.
      Species: Human
      Sample Type: Vaginal Lavage
    184. Human plasmacytoid dendritic cells activated by CpG oligodeoxynucleotides induce the generation of CD4+CD25+ regulatory T cells.
      Authors: Moseman EA, Liang X, Dawson AJ, Panoskaltsis-Mortari A, Krieg AM, Liu YJ, Blazar BR, Chen W
      J. Immunol., 2004;173(7):4433-42.
      Species: Human
      Sample Type: Cell Culture Supernates
    185. Lack of phenotypic and functional impairment in dendritic cells from chimpanzees chronically infected with hepatitis C virus.
      Authors: Larsson M, Babcock E, Grakoui A, Shoukry N, Lauer G, Rice C, Walker C, Bhardwaj N
      J. Virol., 2004;78(12):6151-61.
      Species: Primate - Pan troglodytes (Chimpanzee)
      Sample Type: Cell Culture Supernates
    186. High concentrations of circulating macrophage migration inhibitory factor in patients with severe blunt trauma: Is serum macrophage migration inhibitory factor concentration a valuable prognostic factor?
      Authors: Chuang CC, Hung CJ, Tsai MC, Chuang YC
      Crit. Care Med., 2004;32(3):734-9.
      Species: Human
      Sample Type: Serum
    187. Tumour necrosis factor-alpha transcription in transferrin-stimulated human blood mononuclear cells: is transferrin receptor involved in the signalling mechanism?
      Authors: Lopez M, Rios E, Schlesinger L, Olivares M, Nunez MT, Munoz C
      Br. J. Haematol., 2003;120(5):829-35.
      Species: Human
      Sample Type: Cell Culture Supernates
    188. Shifts in biochemical markers associated with wound healing in laryngeal secretions following phonotrauma: a preliminary study.
      Authors: Verdolini K, Rosen CA, Branski RC, Hebda PA
      Ann. Otol. Rhinol. Laryngol., 2003;112(12):1021-5.
      Species: Human
      Sample Type: Tissue Secretion
    189. Antidiabetic PPAR gamma-activator rosiglitazone reduces MMP-9 serum levels in type 2 diabetic patients with coronary artery disease.
      Authors: Marx N, Froehlich J, Siam L, Ittner J, Wierse G, Schmidt A, Scharnagl H, Hombach V, Koenig W
      Arterioscler. Thromb. Vasc. Biol., 2003;23(2):283-8.
      Species: Human
      Sample Type: Serum
    190. The significance of cytokines, chemical composition, and murine embryo development in hydrosalpinx fluid for predicting the IVF outcome in women with hydrosalpinx.
      Authors: Chen CD, Yang JH, Lin KC, Chao KH, Ho HN, Yang YS
      Hum. Reprod., 2002;17(1):128-33.
      Species: Human
      Sample Type: Hydrosalpinx Fluid
    191. Fibroblasts from human spleen regulate NK cell differentiation from blood CD34(+) progenitors via cell surface IL-15.
      Authors: Briard D, Brouty-Boye D, Azzarone B, Jasmin C
      J. Immunol., 2002;168(9):4326-32.
      Species: Human
      Sample Type: Cell Culture Supernates
    192. Local immunostimulation induced by intravesical administration of autologous interferon-gamma-activated macrophages in patients with superficial bladder cancer.
      Authors: Pages F, Lebel-Binay S, Vieillefond A, Deneux L, Cambillau M, Soubrane O, Debre B, Tardy D, Lemonne JL, Abastado JP, Fridman WH, Thiounn N
      Clin. Exp. Immunol., 2002;127(2):303-9.
      Species: Human
      Sample Type: Urine
    193. Analysis of chemokines and chemokine receptor expression in ovarian cancer ascites.
      Authors: Milliken D, Scotton C, Raju S, Balkwill F, Wilson J
      Clin. Cancer Res., 2002;8(4):1108-14.
      Species: Human
      Sample Type: Plasma
    194. Intraperitoneal bispecific antibody (HEA125xOKT3) therapy inhibits malignant ascites production in advanced ovarian carcinoma.
      Authors: Marme A, Strauss G, Bastert G, Grischke EM, Moldenhauer G
      Int. J. Cancer, 2002;101(2):183-9.
      Species: Human
      Sample Type: Ascites Fluid
    195. Interleukin-11 induces Th2 polarization of human CD4(+) T cells.
      Authors: Curti A, Ratta M, Corinti S, Girolomoni G, Ricci F, Tazzari P, Siena M, Grande A, Fogli M, Tura S, Lemoli RM
      Blood, 2001;97(9):2758-63.
      Species: Human
      Sample Type: Cell Culture Supernates
    196. Interleukin-6 is a major effector molecule of short-term G-CSF treatment inducing bone metabolism and an acute-phase response.
      Authors: Carstanjen D, Regenfus M, Muller C, Salama A
      Exp. Hematol., 2001;29(7):812-21.
      Species: Human
      Sample Type: Serum
    197. A cytokine-to-chemokine axis between T lymphocytes and keratinocytes can favor Th1 cell accumulation in chronic inflammatory skin diseases.
      Authors: Albanesi C, Scarponi C, Sebastiani S, Cavani A, Federici M, Sozzani S, Girolomoni G
      J. Leukoc. Biol., 2001;70(4):617-23.
      Species: Human
      Sample Type: Cell Culture Supernates
    198. Cyclic mechanical stretching modulates secretion pattern of growth factors in human tendon fibroblasts.
      Authors: Skutek M, van Griensven M, Zeichen J, Brauer N, Bosch U
      Eur. J. Appl. Physiol., 2001;86(1):48-52.
      Species: Human
      Sample Type: Cell Culture Supernates
    199. An analysis of acute changes in interleukin-6 levels after treatment of hepatitis C with consensus interferon.
      Authors: Cotler SJ, Reddy KR, McCone J, Wolfe DL, Liu A, Craft TR, Ferris MW, Conrad AJ, Albrecht J, Morrissey M, Ganger DR, Rosenblate H, Blatt LM, Jensen DM, Taylor MW
      J. Interferon Cytokine Res., 2001;21(12):1011-9.
      Species: Human
      Sample Type: Serum
    200. Effects of UVB radiation on cytokine generation, cell adhesion molecules, and cell activation markers in T-lymphocytes and peripheral blood HPCs.
      Authors: Lankford KV, Mosunjac M, Hillyer CD
      Transfusion, 2000;40(3):361-7.
      Species: Human
      Sample Type: Cell Culture Supernates
    201. High versus low basal cortisol secretion in asymptomatic, medication-free HIV-infected men: differential effects of severe life stress on parameters of immune status.
      Authors: Petitto JM, Leserman J, Perkins DO, Stern RA, Silva SG, Gettes D, Zheng B, Folds JD, Golden RN, Evans DL
      Behav Med, 2000;25(4):143-51.
      Species: Human
      Sample Type: Cell Culture Supernates
    202. Amyloid beta and amylin fibrils induce increases in proinflammatory cytokine and chemokine production by THP-1 cells and murine microglia.
      Authors: Yates SL, Burgess LH, Kocsis-Angle J, Antal JM, Dority MD, Embury PB, Piotrkowski AM, Brunden KR
      J. Neurochem., 2000;74(3):1017-25.
      Species: Human
      Sample Type: Cell Culture Supernates
    203. A pilot study of pentoxifylline for the treatment of primary sclerosing cholangitis.
      Authors: Bharucha AE, Jorgensen R, Lichtman SN, LaRusso NF, Lindor KD
      Am. J. Gastroenterol., 2000;95(9):2338-42.
      Species: Human
      Sample Type: Serum
    204. Cytokine production in rhesus monkeys infected with Plasmodium coatneyi.
      Authors: Yang C, Xiao L, Tongren JE, Sullivan J, Lal AA, Collins WE
      Am. J. Trop. Med. Hyg., 1999;61(2):226-9.
      Species: Primate
      Sample Type: Serum
    205. Macrophages that have ingested apoptotic cells in vitro inhibit proinflammatory cytokine production through autocrine/paracrine mechanisms involving TGF-beta, PGE2, and PAF.
      Authors: Fadok, V A, Bratton, D L, Konowal, A, Freed, P W, Westcott, J Y, Henson, P M
      J Clin Invest, 1998;101(4):890-8.
      Species: Human
      Sample Type: Cell Culture Supernates
    206. A syndrome of peripheral lipodystrophy, hyperlipidaemia and insulin resistance in patients receiving HIV protease inhibitors.
      Authors: Carr, A, Samaras, K, Burton, S, Law, M, Freund, J, Chisholm, D J, Cooper, D A
      AIDS, 1998;12(7):F51-8.
      Species: Human
      Sample Type: Serum
    207. Serum levels of interleukins, growth factors and angiogenin in patients with endometrial cancer.
      Authors: Chopra V, Dinh TV, Hannigan EV
      J. Cancer Res. Clin. Oncol., 1997;123(3):167-72.
      Species: Human
      Sample Type: Serum
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    Average Rating: 4.4 (Based on 7 reviews)

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     Human TNF-alpha Quantikine ELISA Kit DTA00C
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    Excellent
      Anonymous 10/18/2017
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     Human TNF-alpha Quantikine ELISA Kit DTA00C
    : Human TNF-alpha Quantikine ELISA Kit [DTA00C]

    Summary

    Sample TestedCell Culture Supernates
     Human TNF-alpha Quantikine ELISA Kit DTA00C
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      Anonymous 07/25/2017
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     Human TNF-alpha Quantikine ELISA Kit DTA00C
    : Human TNF-alpha Quantikine ELISA Kit [DTA00C]

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    Sample TestedMesenchymal stem cells
     Human TNF-alpha Quantikine ELISA Kit DTA00C
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      Anonymous 06/20/2017
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     Human TNF-alpha Quantikine ELISA Kit DTA00C
    : Human TNF-alpha Quantikine ELISA Kit [DTA00C]

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    Sample TestedEDTA Plasma

    Other Experimental Details

    Other Experimental Detailsstandard curve is not very riproducibile and often it is not very precise as it appears in the datasheet
     Human TNF-alpha Quantikine ELISA Kit DTA00C
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      Anonymous 04/24/2017
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     Human TNF-alpha Quantikine ELISA Kit DTA00C
    : Human TNF-alpha Quantikine ELISA Kit [DTA00C]

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    Sample TestedSerum

    Other Experimental Details

    Other Experimental DetailsHuman serum samples used as a dilution of 1 in 10 in DI water initially and the samples did not have expression of TNFa. To confirm the ELISA was run for a second time with a dilution of 1 in 5 and we found some expression but very little.
     Human TNF-alpha Quantikine ELISA Kit DTA00C
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      Anonymous 04/24/2017
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     Human TNF-alpha Quantikine ELISA Kit DTA00C
    : Human TNF-alpha Quantikine ELISA Kit [DTA00C]

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    Sample TestedSerum

    Other Experimental Details

    Other Experimental DetailsThe TNF-alpha Quantikine ELISA kit is used for Diagnostic use.
     Human TNF-alpha Quantikine ELISA Kit DTA00C
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      Anonymous 03/03/2017
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     Human TNF-alpha Quantikine ELISA Kit DTA00C
    : Human TNF-alpha Quantikine ELISA Kit [DTA00C]

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    Sample TestedPeripheral blood mononuclear cells (PBMCs)
     Human TNF-alpha Quantikine ELISA Kit DTA00C
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      Human Anonymous 10/26/2015
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     Human TNF-alpha Quantikine ELISA Kit DTA00C
    : Human TNF-alpha Quantikine ELISA Kit [DTA00C]

    Summary

    Sample TestedDendritic cells
    SpeciesHuman

    Other Experimental Details

    Other Experimental DetailsStandard curve is shown.
    Buffer: kit dilution buffer
    Dilution: 1/100

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