Human TNF RI/TNFRSF1A APC-conjugated Antibody

Catalog # Availability Size / Price Qty
FAB225A
Detection of TNF RI/TNFRSF1A in Human Blood Monocytes by Flow Cytometry.
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Product Details
Citations (4)
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Human TNF RI/TNFRSF1A APC-conjugated Antibody Summary

Species Reactivity
Human
Specificity
Detects human TNF RI in Western blots. In Western blots, does not cross-react with recombinant human TNF RII, recombinant mouse (rm) TNF RI, or rmTNF RII.
Source
Monoclonal Mouse IgG1 Clone # 16803
Purification
Protein A or G purified from ascites
Immunogen
E. coli-derived recombinant human TNF RI/TNFRSF1A
Accession # NP_001056
Formulation
Supplied in a saline solution containing BSA and Sodium Azide.
Label
Allophycocyanin (Excitation= 620-650 nm, Emission= 660-670 nm)

Applications

Recommended Concentration
Sample
Flow Cytometry
10 µL/106 cells
See below

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Scientific Data

Flow Cytometry Detection of TNF RI/TNFRSF1A antibody in Human Blood Monocytes antibody by Flow Cytometry. View Larger

Detection of TNF RI/TNFRSF1A in Human Blood Monocytes by Flow Cytometry. Human peripheral blood monocytes were stained with Mouse Anti-Human TNF RI/TNFRSF1A APC-conjugated Monoclonal Antibody (Catalog # FAB225A, filled histogram) or isotype control antibody (Catalog # IC002A, open histogram). View our protocol for Staining Membrane-associated Proteins.

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Preparation and Storage

Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Protect from light. Do not freeze.
  • 12 months from date of receipt, 2 to 8 °C as supplied.

Background: TNF RI/TNFRSF1A

TNF RI occurs both in membrane bound and soluble forms and functions as a receptor for TNF-alpha and TNF-beta. In the superfamily nomenclature, it is designated TNFRSF1A.

Long Name
Tumor Necrosis Factor Receptor I
Entrez Gene IDs
7132 (Human); 21937 (Mouse); 25625 (Rat); 102135285 (Cynomolgus Monkey)
Alternate Names
CD120a antigen; CD120a; FPF; p55; p55-R; p60; TNF RI; TNFARMGC19588; TNF-R; TNF-R1; TNFR1TBP1; TNFR55; TNF-R55; TNFR60; TNFRI; TNF-RI; TNF-R-I; TNFR-I; TNFRSF1A; tumor necrosis factor binding protein 1; Tumor necrosis factor receptor 1; tumor necrosis factor receptor 1A isoform beta; tumor necrosis factor receptor superfamily member 1A; tumor necrosis factor receptor superfamily, member 1A; tumor necrosis factor receptor type 1; Tumor necrosis factor receptor type I; tumor necrosis factor-alpha receptor

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Citations for Human TNF RI/TNFRSF1A APC-conjugated Antibody

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

4 Citations: Showing 1 - 4
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  1. TNF-alpha Affects Signature Cytokines of Th1 and Th17 T Cell Subsets through Differential Actions on TNFR1 and TNFR2
    Authors: B Pesce, CH Ribeiro, M Larrondo, V Ramos, L Soto, D Catalán, JC Aguillón
    International Journal of Molecular Sciences, 2022;23(16):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  2. Co-expression of TNF receptors 1 and 2 on melanomas facilitates soluble TNF-induced resistance to MAPK pathway inhibitors
    Authors: CA Sander, EA Rush, J Shi, LMRB Arantes, RJ Tesi, MA Ross, MJ Calderon, SC Watkins, JM Kirkwood, RL Ferris, LH Butterfiel, L Vujanovic
    Journal of Translational Medicine, 2022;20(1):331.
    Species: Human
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  3. An in-depth comparison of latent HIV-1 reactivation in multiple cell model systems and resting CD4+ T cells from aviremic patients.
    Authors: Spina, Celsa A, Anderson, Jenny, Archin, Nancie M, Bosque, Alberto, Chan, Jonathan, Famiglietti, Marylind, Greene, Warner C, Kashuba, Angela, Lewin, Sharon R, Margolis, David M, Mau, Matthew, Ruelas, Debbie, Saleh, Suha, Shirakawa, Kotaro, Siliciano, Robert F, Singhania, Akul, Soto, Paula C, Terry, Valeri H, Verdin, Eric, Woelk, Christop, Wooden, Stacey, Xing, Sifei, Planelles, Vicente
    PLoS Pathog, 2013;9(12):e1003834.
    Species: Human
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  4. Differential expression of TNFR1 (CD120a) and TNFR2 (CD120b) on subpopulations of human monocytes.
    Authors: Hijdra D, Vorselaars A, Grutters J, Claessen A, Rijkers G
    J Inflamm (Lond), 2012;9(1):38.
    Species: Human
    Sample Types: Whole Cells
    Applications: Flow Cytometry

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