Human TOMM20 Alexa Fluor® 405-conjugated Antibody Summary
Accession # Q15388
Applications
Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.
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Preparation and Storage
Background: TOMM20
TOMM20 (Translocase of Outer Mitochondrial Membrane 20) is a receptor and key unit of the TOM complex. The TOM complex translocates proteins produced from nuclear DNA through the mitochondrial membrane for use in oxidative phosphorylation. TOMM20 is a conserved outer membrane protein and depletion of TOMM20 produces a large number of dysfunctional mitochondria with the loss of membrane potential. Increased TOMM20 expression has been associated with malignancy of various cancers and contributes to tumorigenesis.
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