Human TOMM20 Alexa Fluor® 405-conjugated Antibody

Catalog #: FAB11604V Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
FAB11604V-100UG
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Human TOMM20 Alexa Fluor® 405-conjugated Antibody Summary

Species Reactivity
Human
Specificity
Detects a synthetic peptide specific for human TOMM20 containing amino acid 55 in Direct ELISA.
Source
Monoclonal Mouse IgG2b Clone # 1074702
Purification
Protein A or G purified
Immunogen
TOMM20 containing synthetic peptide
Accession # Q15388
Formulation
Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide
Label
Alexa Fluor 405 (Excitation= 405 nm, Emission= 421 nm)

Applications

Recommended Concentration
Sample
Western Blot
Optimal dilution of this antibody should be experimentally determined.
 
Immunohistochemistry
Optimal dilution of this antibody should be experimentally determined.
 
Immunocytochemistry
Optimal dilution of this antibody should be experimentally determined.
 

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

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Preparation and Storage

Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied

Background: TOMM20

TOMM20 (Translocase of Outer Mitochondrial Membrane 20) is a receptor and key unit of the TOM complex.  The TOM complex translocates proteins produced from nuclear DNA through the mitochondrial membrane for use in oxidative phosphorylation.  TOMM20 is a conserved outer membrane protein and depletion of TOMM20 produces a large number of dysfunctional mitochondria with the loss of membrane potential.  Increased TOMM20 expression has been associated with malignancy of various cancers and contributes to tumorigenesis.

Long Name
TOMM20
Entrez Gene IDs
9804 (Human); 67952 (Mouse); 266601 (Rat)
Alternate Names
KIAA0016Outer mitochondrial membrane receptor Tom20; MAS20; MGC117367; mitochondrial 20 kDa outer membrane protein; mitochondrial import receptor subunit TOM20 homolo; mitochondrial import receptor subunit TOM20 homolog; MOM19; outer mitochondrial membrane receptor Tom20; TOM20; TOMM20; translocase of outer mitochondrial membrane 20 hom; translocase of outer mitochondrial membrane 20 homolog (yeast); translocase of outer mitochondrial membrane 20 homolog type II

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