Human Total IkB-alpha Cell-Based ELISA

Name: Human Total IkB-alpha Cell-Based ELISA
Brand: R&D Systems
SKU: KCB4299

Catalog #: KCB4299 Datasheet / COA / SDS

Discontinued Product

KCB4299 has been discontinued.

View all IkB-alpha products.

All IkB-alpha ELISAs

Product Details

FAQs

Reviews

Summary Product Datasheets Preparation and Storage Background

Human Total IkB-alpha Cell-Based ELISA Summary

Alternatively

* Alternatively, this assay can be run over two days, which requires 2 hours 30 mins (day 1) and 4 hours (day 2).

* Provided that the recommended microplates, buffers, diluents, substrates and solutions are used, and the assay is run as summarized in the Assay Procedure provided.

Product Datasheets

Product Datasheet

COA

SDS

Preparation and Storage

Shipping

The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Background: IkB-alpha

The inhibitory IkB proteins (alpha, beta, epsilon) complex with and sequester NFkB family members in the cytoplasm, rendering these transcription factors inactive. When phosphorylated by an active IkB kinase (IKK) complex, IkB proteins are degraded by proteasomes, resulting in the release and nuclear translocation of active NFkB.

Long Name:

I-kappa-B-alpha

Entrez Gene IDs:

4792 (Human); 18035 (Mouse); 25493 (Rat)

Alternate Names:

alpha; I-kappa-B-alpha; IkappaBalphaNF-kappa-B inhibitor alpha; IKBAikB-alpha; IkBalpha; IkB-alpha; MAD3; MAD-3; Major histocompatibility complex enhancer-binding protein MAD3; NFKBI; NFKBIA; nuclear factor of kappa light chain gene enhancer in B-cells; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor