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Human UCH-L1/PGP9.5 Antibody

Catalog #: A-340 Datasheet / COA / SDS

Discontinued Product

A-340 has been discontinued.
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Summary Preparation and Storage Reconstitution Calculator Background Product Datasheets Related Research Areas

Human UCH-L1/PGP9.5 Antibody Summary

Species Reactivity
Human
Specificity
Detects UCH-L1 in Western blots.
Source
Polyclonal Rabbit IgG
Purification
Protein A or G purified
Immunogen
Full-length, highly purified human UCH-L1 protein
Formulation
Supplied in PBS.
Label
Unconjugated

Applications

Recommended Concentration
Sample
Western Blot
Recommendeddilution range for Western blot analysis is 1:100 to 1:1000.
 

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Reconstitution Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

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Preparation and Storage

Shipping
The product is shipped with dry ice or equivalent. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Store unopened vial at -80°C. Avoid repeated freeze-thaw cycles. Aliquot antibody in small volumes prior to freezing.

Background: UCH-L1/PGP9.5

Ubiquitin C-terminal hydrolases are a family of cysteine hydrolases that catalyze the hydrolysis of amides, esters and thioesters from the C-terminus of ubiquitin.  UCH-L1 is a member of the low molecular weight UCHs that processes ubiquitin precursors and ubiquitinated proteins to generate monomeric ubiquitin.  The expression of UCH-L1 is highly specific to cells of the neuroendocrine system and their tumors.  UCH-L1 variants (Ile93Met) have been linked to Parkinson disease and may participate in processes critical for neuronal health.

Long Name
Ubiquitin C-terminal Hydrolase L1
Entrez Gene IDs
7345 (Human); 22223 (Mouse)
Alternate Names
EC 3.4.19.12; EC 6.-; Neuron cytoplasmic protein 9.5; PARK5; PGP 9.5; PGP9.5; PGP9.5Uch-L1; PGP95; ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase); ubiquitin carboxyl-terminal hydrolase isozyme L1; ubiquitin C-terminal hydrolase; Ubiquitin thioesterase L1; UCHL1; UCH-L1

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