Human VEGF-C Quantikine ELISA Kit

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Control Products Available
Human VEGF-C ELISA Cell Culture Supernate/Saliva Standard Curve
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Product Details
Citations (49)
Supplemental Products

Human VEGF-C Quantikine ELISA Kit Summary

Assay Type
Solid Phase Sandwich ELISA
96-well strip plate
Assay Length
4.5 hours
Sample Type & Volume Required Per Well
Cell Culture Supernates (50 uL), Serum (10 uL), EDTA Plasma (50 uL), Platelet-poor Plasma (50 uL), Heparin Plasma (50 uL), Saliva (50 uL)
48.4 pg/mL
Assay Range
109.0 - 7,000 pg/mL (Cell Culture Supernates, Serum, EDTA Plasma, Platelet-poor Plasma, Heparin Plasma, Saliva)
Natural human VEGF-C, recombinant human VEGF-C (wild type), and recombinant human VEGF-C (Cys156Ser substituted)
< 0.5% cross-reactivity observed with available related molecules.Cross-species reactivity not tested.
No significant interference observed with available related molecules.

Product Summary

The Quantikine Human VEGF-C Immunoassay is a 4.5 hour solid-phase ELISA designed to measure human VEGF-C in cell culture supernates, serum, plasma, and saliva. It contains NS0-expressed recombinant human VEGF-C (Cys156Ser substituted) and has been shown to accurately quantitate the recombinant factor. Results obtained using recombinant human VEGF-C (wild type) and natural human VEGF-C showed linear curves that were parallel to the standard curves obtained using the Quantikine kit standards. These results indicate that this kit can be used to determine relative mass values for naturally occurring human VEGF-C.


Intra-Assay Precision (Precision within an assay) Three samples of known concentration were tested on one plate to assess intra-assay precision
Inter-Assay Precision (Precision between assays) Three samples of known concentration were tested in separate assays to assess inter-assay precision

Cell Culture Supernates, Saliva

Intra-Assay Precision Inter-Assay Precision
Sample 1 2 3 1 2 3
n 20 20 20 40 40 40
Mean (pg/mL) 572 1622 3243 520 1527 3069
Standard Deviation 39.3 54.4 136 50.1 102 200
CV% 6.9 3.4 4.2 9.6 6.7 6.5

Serum, EDTA Plasma, Platelet-poor Plasma, Heparin Plasma

Intra-Assay Precision Inter-Assay Precision
Sample 1 2 3 1 2 3
n 20 20 20 40 40 40
Mean (pg/mL) 512 1543 3195 514 1540 3066
Standard Deviation 33.8 54.2 136 43.6 110 198
CV% 6.6 3.5 4.3 8.5 7.2 6.4


The recovery of VEGF-C spiked to levels throughout the range of the assay in various matrices was evaluated.

Sample Type Average % Recovery Range %
Cell Culture Supernates (n=4) 107 93-115
EDTA Plasma (n=4) 101 96-110
Heparin Plasma (n=4) 97 88-103
Serum (n=4) 99 89-106


To assess the linearity of the assay, samples containing and/or spiked with high concentrations of VEGF-C were serially diluted with the appropriate Calibrator Diluent to produce samples with values within the dynamic range of the assay.
Human VEGF-C ELISA Linearity

Scientific Data

Human VEGF-C ELISA Cell Culture Supernate/Saliva Standard Curve

Human VEGF-C ELISA Serum/Plasma Standard Curve

Product Datasheets

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Preparation and Storage

The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Background: VEGF-C

Vascular endothelial growth factor C (VEGF-C) is a homodimeric ligand of VEGF R3/Flt-4 and is synthesized with N- and C-terminal propeptides. Fully processed VEGF-C containing only the VEGF homology domain can additionally bind and activate VEGF R2/KDR/Flk-1. VEGF-C interactions with VEGF R3 are critical for lymphangiogenesis. Both the ligand and receptor are usually co-expressed at sites of lymphatic vessel sprouting, in the embryo, and in various pathological conditions. Over-expression of VEGF-C in tumor cells induces tumoral lymphatic hyperplasia, neoangiogenesis, and vessel sprouting, resulting in enhanced lymph flow and metastasis to regional lymph nodes.

Long Name:
Vascular Endothelial Growth Factor C
Entrez Gene IDs:
7424 (Human); 22341 (Mouse)
Alternate Names:
Flt4 ligand; Flt4-L; vascular endothelial growth factor C; Vascular endothelial growth factor-related protein; VEGFC; VEGF-C; VRPFLT4 ligand DHM
⚠ WARNING: This product can expose you to chemicals including N,N-Dimethylforamide, which is known to the State of California to cause cancer. For more information, go to

Assay Procedure

Refer to the product for complete assay procedure.

Bring all reagents and samples to room temperature before use. It is recommended that all samples, standards, and controls be assayed in duplicate.
  1.   Prepare all reagents, standard dilutions, and samples as directed in the product insert.
  2.   Remove excess microplate strips from the plate frame, return them to the foil pouch containing the desiccant pack, and reseal.

  3. 100 µL Assay Diluent
  4.   Add 100 µL of Assay Diluent to each well.

  5. 50 µL Standard, Control, or Sample
  6.   Add 50 µL of Standard, control, or sample to each well. Cover with a plate sealer, and incubate at room temperature for 2 hours on a horizontal orbital microplate shaker.
  7.   Aspirate each well and wash, repeating the process 3 times for a total of 4 washes.

  8. 200 µL Conjugate
  9.   Add 200 µL of Conjugate to each well. Cover with a new plate sealer, and incubate at room temperature for 2 hours on the shaker.
  10.   Aspirate and wash 4 times.

  11. 200 µL Substrate Solution
  12.   Add 200 µL Substrate Solution to each well. Incubate at room temperature for 30 minutes on the benchtop. PROTECT FROM LIGHT.

  13. 50 µL Stop Solution
  14.   Add 50 µL of Stop Solution to each well. Read at 450 nm within 30 minutes. Set wavelength correction to 540 nm or 570 nm.

Citations for Human VEGF-C Quantikine ELISA Kit

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

49 Citations: Showing 1 - 10
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  1. Dicarbonyl-modified lipoproteins contribute to proteinuric kidney injury
    Authors: J Zhong, HC Yang, EL Shelton, T Matsusaka, AJ Clark, V Yermalitsk, Z Mashhadi, LS May-Zhang, MF Linton, AB Fogo, A Kirabo, SS Davies, V Kon
    JCI Insight, 2022;7(21):.
    Species: Human
    Sample Types: Cell Lysates
  2. Hydrogen Sulfide Attenuates Lymphedema Via the Induction of Lymphangiogenesis Through a PI3K/Akt-Dependent Mechanism
    Authors: J Suzuki, Y Shimizu, T Hayashi, Y Che, Z Pu, K Tsuzuki, S Narita, R Shibata, I Ishii, JW Calvert, T Murohara
    Journal of the American Heart Association, 2022;11(21):e026889.
    Species: Human
    Sample Types: Cell Lysates
  3. Platelet-derived growth factor BB is reduced in endometrial endothelial cells of women with abnormal uterine bleeding-endometrial disorder
    Authors: S Biswas Shi, Q Lu, D Sun, H Hou, JN Bulmer, BA Innes, DK Hapangama, GE Lash
    Oncogene, 2022;0(0):.
    Species: Human
    Sample Types: Cell Culture Supernates
  4. CCT5 induces epithelial-mesenchymal transition to promote gastric cancer lymph node metastasis by activating the Wnt/beta-catenin signalling pathway
    Authors: Y Li, C Liu, X Zhang, X Huang, S Liang, F Xing, H Tian
    British Journal of Cancer, 2022;0(0):.
    Species: Human
    Sample Types: Cell Culture Supernates
  5. Implementing subtype-specific pre-clinical models of breast cancer to study pre-treatment aspirin effects
    Authors: IS Miller, S Khan, LP Shiels, S Das, AC O' Farrell, K Connor, A Lafferty, B Moran, C Isella, P Loadman, E Conroy, S Cohrs, R Schibli, RS Kerbel, WM Gallagher, E Marangoni, K Bennett, DP O' Connor, RM Dwyer, AT Byrne
    Cancer Medicine, 2022;0(0):.
    Species: Human
    Sample Types: Cell Culture Supernates
  6. Retinal VEGF-A Overexpression Is Not Sufficient to Induce Lymphangiogenesis Regardless of VEGF-C Upregulation and Lyve1+ Macrophage Infiltration
    Authors: I Wada, S Nakao, M Yamaguchi, Y Kaizu, M Arima, S Sawa, KH Sonoda
    Investigative Ophthalmology & Visual Science, 2021;62(13):17.
    Species: Human
    Sample Types: Vitreous Humor
  7. Neutralization of the induced VEGF-A potentiates the therapeutic effect of an anti-VEGFR2 antibody on gastric cancer in vivo
    Authors: T Mashima, T Wakatsuki, N Kawata, MK Jang, A Nagamori, H Yoshida, K Nakamura, T Migita, H Seimiya, K Yamaguchi
    Scientific Reports, 2021;11(1):15125.
    Species: Mouse
    Sample Types: Plasma
  8. Comparison of lung ultrasound and other volumetric methods in peritoneal dialysis patients
    Authors: M Sevinc, NB Hasbal, T Basturk, PN Ozcafer, BB Kocas, K Kilickesme, A Ozel, T Sakaci, E Ahbap, A Unsal, Y Koc
    Medicine, 2021;100(3):e23856.
    Species: Human
    Sample Types: Serum
  9. Extracellular vesicle-associated VEGF-C promotes lymphangiogenesis and immune cells infiltration in endometriosis
    Authors: WN Li, KY Hsiao, CA Wang, N Chang, PL Hsu, CH Sun, SR Wu, MH Wu, SJ Tsai
    Proc Natl Acad Sci U S A, 2020;0(0):.
    Species: Human
    Sample Types: Serum
  10. Distinct Characteristics of VEGF-D and VEGF-C to Predict Mortality in Patients With Suspected or Known Coronary Artery Disease
    Authors: H Wada, M Suzuki, M Matsuda, Y Ajiro, T Shinozaki, S Sakagami, K Yonezawa, M Shimizu, J Funada, T Takenaka, Y Morita, T Nakamura, K Fujimoto, H Matsubara, T Kato, T Unoki, D Takagi, K Wada, M Wada, M Iguchi, N Masunaga, M Ishii, H Yamakage, T Kusakabe, A Yasoda, A Shimatsu, K Kotani, N Satoh-Asah, M Abe, M Akao, K Hasegawa,
    J Am Heart Assoc, 2020;9(9):e015761.
    Species: Human
    Sample Types: Serum
  11. GRK2-Dependent HuR Phosphorylation Regulates HIF1&alpha Activation under Hypoxia or Adrenergic Stress
    Authors: C Reglero, V Lafarga, V Rivas, Á Albitre, P Ramos, SR Berciano, O Tapia, ML Martínez-C, F Mayor, P Penela
    Cancers (Basel), 2020;12(5):.
    Species: Human
    Sample Types: Cell Lysates
  12. Phase Ib/II Clinical Trial of Pembrolizumab With Bevacizumab for Metastatic Renal Cell Carcinoma: BTCRC-GU14-003
    Authors: AZ Dudek, LC Liu, S Gupta, TF Logan, EA Singer, M Joshi, YN Zakharia, JM Lang, JK Schwarz, A Al-Janadi, AS Alva
    J. Clin. Oncol., 2020;38(11):1138-1145.
    Species: Human
    Sample Types: Serum
  13. Distribution and Activity of Lenvatinib in Brain Tumor Models of Human Anaplastic Thyroid Cancer Cells in Severe Combined Immune Deficient Mice
    Authors: R Wang, T Yamada, S Arai, K Fukuda, H Taniguchi, A Tanimoto, A Nishiyama, S Takeuchi, K Yamashita, K Ohtsubo, J Matsui, N Onoda, E Hirata, S Taira, S Yano
    Mol. Cancer Ther., 2019;18(5):947-956.
    Species: Human
    Sample Types: Cell Culture Supernates
  14. KLK3/PSA and cathepsin D activate VEGF-C and VEGF-D
    Authors: SK Jha, K Rauniyar, E Chronowska, K Mattonet, EW Maina, H Koistinen, UH Stenman, K Alitalo, M Jeltsch
    Elife, 2019;8(0):.
    Species: Human
    Sample Types: Seminal Plasma
  15. Antibody-mediated delivery of VEGF-C potently reduces chronic skin inflammation
    Authors: S Schwager, S Renner, T Hemmerle, S Karaman, ST Proulx, R Fetz, AM Golding-Oc, P Probst, C Halin, D Neri, M Detmar
    JCI Insight, 2018;3(23):.
    Species: Mouse
    Sample Types: Serum
  16. RIP1 regulates TNF-?-mediated lymphangiogenesis and lymphatic metastasis in gallbladder cancer by modulating the NF-?B-VEGF-C pathway
    Authors: CZ Li, XJ Jiang, B Lin, HJ Hong, SY Zhu, L Jiang, XQ Wang, NH Tang, FF She, YL Chen
    Onco Targets Ther, 2018;11(0):2875-2890.
    Species: Human
    Sample Types: Cell Culture Supernates
  17. Docetaxel facilitates lymphatic-tumor crosstalk to promote lymphangiogenesis and cancer progression
    Authors: AR Harris, MJ Perez, JM Munson
    BMC Cancer, 2018;18(1):718.
    Species: Mouse
    Sample Types: Tissue Homogenates
  18. cIAP2 promotes gallbladder cancer invasion and lymphangiogenesis by activating the NF-?B pathway
    Authors: X Jiang, C Li, B Lin, H Hong, L Jiang, S Zhu, X Wang, N Tang, X Li, F She, Y Chen
    Cancer Sci., 2017;108(6):1144-1156.
    Species: Human
    Sample Types: Cell Culture Supernates
  19. Human neural stem cell-induced endothelial morphogenesis requires autocrine/paracrine and juxtacrine signaling
    Sci Rep, 2016;6(0):29029.
    Species: Human
    Sample Types: Cell Culture Supernates
  20. Effects of fatty acid synthase inhibitors on lymphatic vessels: an in vitro and in vivo study in a melanoma model
    Authors: Débora C Bastos
    Lab. Invest, 2016;0(0):.
    Species: Human
    Sample Types: Cell Culture Supernates
  21. Vascular endothelial growth factor A is associated with the subsequent development of moderate or severe cardiac allograft vasculopathy in pediatric heart transplant recipients
    Authors: David M Briscoe
    J. Heart Lung Transplant., 2016;0(0):.
    Species: Human
    Sample Types: Plasma
  22. Identification of tumour-reactive lymphatic endothelial cells capable of inducing progression of gastric cancer.
    Authors: Tokumoto M, Tanaka H, Tauchi Y, Kasashima H, Kurata K, Yashiro M, Sakurai K, Toyokawa T, Kubo N, Amano R, Kimura K, Muguruma K, Maeda K, Ohira M, Hirakawa K
    Br J Cancer, 2015;113(7):1046-54.
    Species: Human
    Sample Types: Cell Culture Supernates
  23. The role of CCL21/CCR7 chemokine axis in breast cancer-induced lymphangiogenesis.
    Authors: Tutunea-Fatan, Elena, Majumder, Mousumi, Xin, Xiping, Lala, Peeyush
    Mol Cancer, 2015;14(1):35.
    Species: Human
    Sample Types: Cell Culture Supernates
  24. Telmisartan, a possible PPAR-delta agonist, reduces TNF-alpha-stimulated VEGF-C production by inhibiting the p38MAPK/HSP27 pathway in human proximal renal tubular cells.
    Authors: Kimura H, Mikami D, Kamiyama K, Sugimoto H, Kasuno K, Takahashi N, Yoshida H, Iwano M
    Biochem Biophys Res Commun, 2014;454(2):320-7.
    Species: Human
    Sample Types: Cell Culture Supernates
  25. KML001 inhibits cell proliferation and invasion in pancreatic cancer cells through suppression of NF-kappaB and VEGF-C.
    Authors: Yang M, Kim H, Lee K, Yang S, Lee J, Lee K, Rhee J
    Anticancer Res, 2014;34(7):3469-74.
    Species: Human
    Sample Types: Cell Culture Supernates
  26. Filarial excretory-secretory products induce human monocytes to produce lymphangiogenic mediators.
    Authors: Weinkopff T, Mackenzie C, Eversole R, Lammie P
    PLoS Negl Trop Dis, 2014;8(7):e2893.
    Species: Human
    Sample Types: Cell Culture Supernates
  27. Serum angiopoietin-2 and soluble VEGFR-2 levels predict malignancy of ovarian neoplasm and poor prognosis in epithelial ovarian cancer.
    Authors: Sallinen H, Heikura T, Koponen J, Kosma V, Heinonen S, Yla-Herttuala S, Anttila M
    BMC Cancer, 2014;14(0):696.
    Species: Human
    Sample Types: Serum
  28. Vascular endothelial growth factor c promotes ovarian carcinoma progression through paracrine and autocrine mechanisms.
    Authors: Decio A, Taraboletti G, Patton V, Alzani R, Perego P, Fruscio R, Jurgensmeier J, Giavazzi R, Belotti D
    Am J Pathol, 2014;184(4):1050-61.
    Species: Human
    Sample Types: Ascites Fluid
  29. Role of serum concentration of VEGFR1 and TIMP2 on clinical outcome in primary cervical cancer: results of a companion protocol of the randomized, NOGGO-AGO phase III adjuvant trial of simultaneous cisplatin-based radiochemotherapy vs. carboplatin and paclitaxel containing sequential radiotherapy.
    Authors: Braicu E, Fotopoulou C, Chekerov R, Richter R, Blohmer J, Kummel S, Stamatian F, Yalcinkaya I, Mentze M, Lichtenegger W, Sehouli J
    Cytokine, 2013;61(3):755-8.
    Species: Human
    Sample Types: Serum
  30. Long-term survival and biomarker correlates of tasquinimod efficacy in a multicenter randomized study of men with minimally symptomatic metastatic castration-resistant prostate cancer.
    Authors: Armstrong A, Haggman M, Stadler W, Gingrich J, Assikis V, Polikoff J, Damber J, Belkoff L, Nordle O, Forsberg G, Carducci M, Pili R
    Clin Cancer Res, 2013;19(24):6891-901.
    Species: Human
    Sample Types: Plasma
  31. Proteinuria triggers renal lymphangiogenesis prior to the development of interstitial fibrosis.
    Authors: Yazdani S, Poosti F, Kramer A, Mirkovic K, Kwakernaak A, Hovingh M, Slagman M, Sjollema K, de Borst M, Navis G, van Goor H, van den Born J
    PLoS ONE, 2012;7(11):e50209.
    Species: Human
    Sample Types: Cell Culture Supernates
  32. Co-expression of alpha9beta1 integrin and VEGF-D confers lymphatic metastatic ability to a human breast cancer cell line MDA-MB-468LN.
    Authors: Majumder M, Tutunea-Fatan E, Xin X, Rodriguez-Torres M, Torres-Garcia J, Wiebe R, Timoshenko AV, Bhattacharjee RN, Chambers AF, Lala PK
    PLoS ONE, 2012;7(4):e35094.
    Species: Human
    Sample Types: Cell Culture Supernates
  33. Lysophosphatidic Acid Enhances Vascular Endothelial Growth Factor-C Expression in Human Prostate Cancer PC-3 Cells.
    Authors: Lin CE, Chen SU, Lin CC
    PLoS ONE, 2012;7(7):e41096.
    Species: Human
    Sample Types: Cell Culture Supernates
  34. Mechanism-related circulating proteins as biomarkers for clinical outcome in patients with unresectable hepatocellular carcinoma receiving sunitinib.
    Authors: Harmon CS, DePrimo SE, Raymond E, Cheng AL, Boucher E, Douillard JY, Lim HY, Kim JS, Lechuga MJ, Lanzalone S, Lin X, Faivre S
    J Transl Med, 2011;9(0):120.
    Species: Human
    Sample Types: Plasma
  35. Paracrine and autocrine signals induce and maintain mesenchymal and stem cell states in the breast.
    Authors: Scheel C, Eaton E, Li S, Chaffer C, Reinhardt F, Kah K, Bell G, Guo W, Rubin J, Richardson A, Weinberg R
    Cell, 2011;145(6):926-40.
    Species: Human
    Sample Types: Cell Culture Supernates
  36. Prognostic significance of angiogenic factors in uterine cervical cancer.
    Authors: Landt S, Wehling M, Heidecke H, Jeschke S, Korlach S, Stoblen F, Schmid P, Blohmer JU, Lichtenegger W, Sehouli J, Kummel S
    Anticancer Res., 2011;31(8):2589-95.
    Species: Human
    Sample Types: Serum
  37. Human pregnancy specific beta-1-glycoprotein 1 (PSG1) has a potential role in placental vascular morphogenesis.
    Authors: Ha CT, Wu JA, Irmak S, Lisboa FA, Dizon AM, Warren JW, Ergun S, Dveksler GS
    Biol. Reprod., 2010;83(1):27-35.
    Species: Human
    Sample Types: Cell Culture Supernates
  38. Phase I and pharmacological study of the broad-spectrum tyrosine kinase inhibitor JNJ-26483327 in patients with advanced solid tumours.
    Authors: Konings IR, de Jonge MJ, Burger H
    Br. J. Cancer, 2010;103(7):987-92.
    Species: Human
    Sample Types: Serum
  39. VEGF-C regulates lymphangiogenesis and capillary stability by regulation of PDGF-B.
    Authors: Onimaru M, Yonemitsu Y, Fujii T, Tanii M, Nakano T, Nakagawa K, Kohno R, Hasegawa M, Nishikawa S, Sueishi K
    Am. J. Physiol. Heart Circ. Physiol., 2009;297(5):H1685-96.
    Species: Human
    Sample Types: Serum
  40. Macrophages regulate salt-dependent volume and blood pressure by a vascular endothelial growth factor-C-dependent buffering mechanism.
    Authors: Machnik A, Neuhofer W, Jantsch J, Dahlmann A, Tammela T, Machura K, Park JK, Beck FX, Muller DN, Derer W, Goss J, Ziomber A, Dietsch P, Wagner H, Van Rooijen N, Kurtz A, Hilgers KF, Alitalo K, Eckardt KU, Luft FC, Kerjaschki D, Titze J
    Nat. Med., 2009;15(5):545-52.
    Species: Human
    Sample Types: Serum
  41. Efficacy, safety, and potential biomarkers of sunitinib monotherapy in advanced hepatocellular carcinoma: a phase II study.
    Authors: Zhu AX, Sahani DV, Duda DG, di Tomaso E, Ancukiewicz M, Catalano OA, Sindhwani V, Blaszkowsky LS, Yoon SS, Lahdenranta J, Bhargava P, Meyerhardt J, Clark JW, Kwak EL, Hezel AF, Miksad R, Abrams TA, Enzinger PC, Fuchs CS, Ryan DP, Jain RK
    J. Clin. Oncol., 2009;27(18):3027-35.
    Species: Human
    Sample Types: Plasma
  42. Antitumor activity and biomarker analysis of sunitinib in patients with bevacizumab-refractory metastatic renal cell carcinoma.
    Authors: Rini BI, Michaelson MD, Rosenberg JE, Bukowski RM, Sosman JA, Stadler WM, Hutson TE, Margolin K, Harmon CS, DePrimo SE, Kim ST, Chen I, George DJ
    J. Clin. Oncol., 2008;26(22):3743-8.
    Species: Human
    Sample Types: Plasma
  43. Hypoxia-induced epithelial VEGF-C/VEGFR-3 upregulation in carcinoma cell lines.
    Authors: Simiantonaki N, Jayasinghe C, Michel-Schmidt R, Peters K, Hermanns MI, Kirkpatrick CJ
    Int. J. Oncol., 2008;32(3):585-92.
    Species: Human
    Sample Types: Cell Culture Supernates
  44. Isolation and characterization of CD146+ multipotent mesenchymal stromal cells.
    Authors: Sorrentino A, Ferracin M, Castelli G, Biffoni M, Tomaselli G, Baiocchi M, Fatica A, Negrini M, Peschle C, Valtieri M
    Exp. Hematol., 2008;36(8):1035-46.
    Species: Human
    Sample Types: Cell Culture Supernates
  45. Cutting edge: rapid accumulation of epidermal CCL27 in skin-draining lymph nodes following topical application of a contact sensitizer recruits CCR10-expressing T cells.
    Authors: Huang V, Lonsdorf AS, Fang L, Kakinuma T, Lee VC, Cha E, Zhang H, Nagao K, Zaleska M, Olszewski WL, Hwang ST
    J. Immunol., 2008;180(10):6462-6.
    Species: Human
    Sample Types: Serum
  46. Expression of Tie-2 and other receptors for endothelial growth factors in acute myeloid leukemias is associated with monocytic features of leukemic blasts.
    Authors: Riccioni R, Diverio D, Mariani G, Buffolino S, Riti V, Saulle E, Petrucci E, Cedrone M, Lo-Coco F, Foa R, Peschle C, Testa U
    Stem Cells, 2007;25(8):1862-71.
    Species: Human
    Sample Types: Cell Culture Supernates
  47. Vascular endothelial growth factor receptor 3 is involved in tumor angiogenesis and growth.
    Authors: Laakkonen P, Waltari M, Holopainen T, Takahashi T, Pytowski B, Steiner P, Hicklin D, Persaud K, Tonra JR, Witte L, Alitalo K
    Cancer Res., 2007;67(2):593-9.
    Species: Human
    Sample Types: Cell Culture Supernates
  48. Marrow angiogenesis-associated factors as prognostic biomarkers in patients with acute myelogenous leukaemia.
    Authors: Lee CY, Tien HF, Hu CY, Chou WC, Lin LI
    Br. J. Cancer, 2007;97(7):877-82.
    Species: Human
    Sample Types: Plasma
  49. Inhibition of lymphogenous metastasis using adeno-associated virus-mediated gene transfer of a soluble VEGFR-3 decoy receptor.
    Authors: Lin J, Lalani AS, Harding TC
    Cancer Res., 2005;65(15):6901-9.
    Species: Human
    Sample Types: Tissue Homogenates


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