Human VIP Alexa Fluor® 488-conjugated Antibody

Catalog # Availability Size / Price Qty
FAB6079G-100UG

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Human VIP Alexa Fluor® 488-conjugated Antibody Summary

Species Reactivity
Human
Specificity
Detects recombinant human VIP in direct ELISAs. It does not detect the C-terminal region (aa 145-152).
Source
Monoclonal Mouse IgG1 Clone # 576721
Purification
Protein A or G purified
Immunogen
KLH-coupled human VIP synthetic peptides HSDAVFTDNYTR and KYLNSILN
Formulation
Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide
Label
Alexa Fluor 488 (Excitation= 488 nm, Emission= 515-545 nm)

Applications

Recommended Concentration
Sample
Immunohistochemistry
Optimal dilution of this antibody should be experimentally determined.
 

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

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Preparation and Storage

Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied

Background: VIP

Vasoactive intestinal peptide (VIP) is a 28 amino acid (aa) peptide that exerts wide-ranging effects in embryonic and adult tissues through interactions with the 7‑transmembrane spanning receptors VIP R1 and VIP R2. The VIP proprotein is proteolytically processed to release bioactive VIP as well as the bioactive peptides PHV and PHM. VIP regulates appetite and feeding behavior and stimulates insulin and glucagon secretion in pancreatic islet cells. It also regulates astrocyte function, multiple aspects of cardiac function, and TLR function in innate immune responses. Mature VIP shares 100% aa sequence identity with mouse and rat VIP.

Long Name
Vasoactive Intestinal Peptide
Entrez Gene IDs
7432 (Human)
Alternate Names
MGC13587; PHM27; vasoactive intestinal peptide; VIP peptides; VIP

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