Iberiotoxin

Tocris Bioscience | Catalog # 1086

KCa (BK) channel blocker
Tocris Bioscience

Key Product Details

Description

KCa (BK) channel blocker
View all Ca2+-Activated Potassium Channel Blockers »

Product Description

Iberiotoxin is a selective blocker of the big conductance Ca2+-activated K+ channel.

Product Specifications for Iberiotoxin

Molecular Weight

4230.00

Formula

C179H274N50O55S7

Storage

Store at -20°C

Purity

≥95% (HPLC)

CAS Number

129203-60-7

PubChem ID

16132435

InChI Key

VDNVVLOBNHIMQA-UHFFFAOYSA-N

SMILES

[H]N1[C@@H](CCC1=O)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@H]1CSSC[C@@H]2NC(=O)[C@H](CCCCN)NC(=O)CNC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(O)=O)NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](CC3=CC=CC=C3)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@@H]3CSSC[C@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CSSC[C@H](NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](CO)NC1=O)C(C)C)C(=O)N[C@@H](CC1=CNC4=C1C=CC=C4)C(=O)N[C@@H](CO)C(=O)N[C@@H](C(C)C)C(=O)N3)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCCN)NC(=O)CNC(=O)[C@H](CCSC)NC2=O)C(=O)N[C@@H](CC1=CC=C(O)C=C1)C(=O)N[C@@H](CCC(N)=O)C(O)=O)C(C)C

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solubility Soluble to 0.7mg/ml in water

Calculators

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Background References

References are publications that support the biological activity of the product. See our Citations tab to view 135 publications citing the usage of this product.

Product Documents for Iberiotoxin

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for Iberiotoxin

For research use only

Related Research Areas

Ion Channels and Regulators

Customer Reviews for Iberiotoxin (1)

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  • Selective blocker worked ideally to block Calcium channels
    Name: Farzana Islam
    Species: Human
    Assay Type: In Vitro
    Cell Line/Tissue: HEK 293
    Verified Customer | Posted 10/02/2018
    High-affinity and specific KCa1.1 channel blocker, used to study how it works to block SK channels. The product dissolved in aqueous buffer and was excellent in the lab conditions. Inhibition of SK channels were observed.
    Iberiotoxin 1086

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