ICI 182,780

  ( 247 citations ) ( 1 Review )    
Product Datasheet
Catalog Number:1047
Chemical Name:7α,17β-[9-[(4,4,5,5,5-Pentafluoropentyl)sulfinyl]nonyl]estra-1,3,5(10)-triene-3,17-diol
Product Details
Citations (247)
Biological Activity
A high affinity estrogen receptor antagonist (IC50 = 0.29 nM), devoid of any partial agonism both in vitro and in vivo. Also high affinity agonist at the membrane estrogen receptor GPER.
Technical Data
  • M.Wt:
  • Formula:
  • Solubility:
    Soluble to 50 mM in ethanol and to 100 mM in DMSO
  • Purity:
  • Storage:
    Store at RT
  • CAS No:
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
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The citations listed below are publications that use Tocris products. Selected citations for ICI 182,780 include:

247 Citations: Showing 1 - 10
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  1. Pancreatic insulin content regulation by the estrogen receptor ER alpha.
    Authors: Alonso-Magdalena Et al.
    PLoS One  ;3:e2069
  2. Estrogen enhances mismatch repair by induction of MLH1 expression via estrogen receptor-β.
    Authors: Lu Et al.
    Oncotarget  2017;8:38767
  3. Structural and molecular mechanisms of cytokine-mediated endocrine resistance in human breast cancer cells.
    Authors: Stender
    Mol Cell  2017;65(6):1122
  4. Estradiol Suppresses TLR4-triggered Apoptosis of Decidual Stromal Cells and Drives an Anti-inflammatory TH2 Shift by Activating SGK1.
    Authors: Lou Et al.
    Int J Biol Sci  2017;13:434
  5. Differential and directional estrogenic signaling pathways induced by enterolignans and their precursors.
    Authors: Zhu
    PLoS One  2017;12(2):e0171390
  6. Identification of Differential ER-Alpha Versus ER-Beta Mediated Activation of eNOS in Ovine Uterine Artery Endothelial Cells.
    Authors: Pastore Et al.
    Biol Reprod  2016;94:139
  7. Low expression of estrogen receptor β in T lymphocytes and high serum levels of anti-estrogen receptor α antibodies impact disease activity in female patients with systemic lupus erythematosus.
    Authors: Maselli Et al.
    Front Vet Sci  2016;7:3
  8. Antiestrogen resistant cell lines expressing estrogen receptor α mutations upregulate the unfolded protein response and are killed by BHPI
    Authors: Mao Et al.
    Scientific Reports  2016;6:34753
  9. Estrogen protects against dopamine neuron toxicity in primary mesencephalic cultures through an indirect P13K/Akt mediated astrocyte pathway.
    Authors: Bains and Roberts
    Neurosci Lett  2016;610:79
  10. NCOA3 coactivator is a transcriptional target of XBP1 and regulates PERK-eIF2α-ATF4 signalling in breast cancer.
    Authors: Gupta Et al.
    Oncogene  2016;35:5860
  11. Endogenous 17β-estradiol is required for activity-dependent long-term potentiation in the striatum: interaction with the dopaminergic system.
    Authors: Tozzi Et al.
    Front Cell Neurosci  2015;9:192
  12. Differential effects of estrogen and estrogen receptor antagonist, ICI 182 780, on the expression of calbindin-D9k in rat pituitary prolactinoma GH3 cells.
    Authors: Wang Et al.
    Cancer Cell Int  2015;7:8498
  13. A cluster of noncoding RNAs activates the ESR1 locus during breast cancer adaptation.
    Authors: Tomita Et al.
    Nat Commun  2015;6:6966
  14. A short report: PAMM, a novel antioxidant protein, induced by oxidative stress.
    Authors: Xu Et al.
    Redox Biol  2015;6:446
  15. Altered radiation responses of breast cancer cells resistant to hormonal therapy.
    Authors: Luzhna Et al.
    Mol Cell Biol  2015;6:1678
  16. Methoxychlor and its metabolite HPTE inhibit cAMP production and expression of estrogen receptors α and β in the rat granulosa cell in vitro.
    Authors: Harvey Et al.
    Reprod Toxicol  2015;51:72
  17. Nodes-and-connections RNAi knockdown screening: identification of a signaling molecule network involved in fulvestrant action and breast cancer prognosis.
    Authors: Miyoshi Et al.
    Biol Sex Differ  2015;4:e172
  18. Differential expression of upstream stimulatory factor (USF) 2 variants in eutopic endometria from women with endometriosis: estradiol regulation.
    Authors: Castro Et al.
    Biol Res  2015;48:56
  19. New cell culture model for aromatase inhibitor-resistant breast cancer shows sensitivity to fulvestrant treatment and cross-resistance between letrozole and exemestane.
    Authors: Hole Et al.
    BMC Cancer  2015;46:1481
  20. NF-κB signaling is required for XBP1 (unspliced and spliced)-mediated effects on antiestrogen responsiveness and cell fate decisions in breast cancer.
    Authors: Hu Et al.
    Oncogenesis  2015;35:379
  21. PHLDA1 expression is controlled by an estrogen receptor-NFκB-miR-181 regulatory loop and is essential for formation of ER+ mammospheres.
    Authors: Kastrati Et al.
    Oncogene  2015;34:2309
  22. The Effects of Steroid Implant and Dietary Soybean Hulls on Estrogenic Activity of Sera of Steers Grazing Toxic Endophyte-Infected Tall Fescue Pasture.
    Authors: Shappell Et al.
    Cancer Lett  2015;2:30
  23. Estrogenic and anti-estrogenic activity of off-the-shelf hair and skin care products.
    Authors: Myers Et al.
    BMC Cancer  2015;25:271
  24. Evaluation of the pharmacological activities of RAD1901, a selective estrogen receptor degrader.
    Authors: Wardell Et al.
    Endocr Relat Cancer  2015;22:713
  25. Aurora kinase B is important for antiestrogen resistant cell growth and a potential biomarker for tamoxifen resistant breast cancer.
    Authors: Larsen Et al.
    Aging Cell  2015;15:239
  26. Antihormonal agents as a strategy to improve the effect of chemo-radiation in cervical cancer: in vitro and in vivo study.
    Authors: Segovia-Mendoza Et al.
    J Biol Chem  2015;15:21
  27. Opposite effects of two estrogen receptors on tau phosphorylation through disparate effects on the miR-218/PTPA pathway.
    Authors: Xiong Et al.
    Breast Cancer Res Treat  2015;14:867
  28. Estrogen mediated expression of nucleophosmin 1 in human endometrial carcinoma clinical stages through estrogen receptor-α signaling.
    Authors: Zhou Et al.
    Endocrinology  2015;14:540
  29. The PI3K/mTOR dual inhibitor P7170 demonstrates potent activity against endocrine-sensitive and endocrine-resistant ER+ breast cancer.
    Authors: Bean Et al.
    Oncotarget  2015;149:69
  30. Estrogen promotes luteolysis by redistributing prostaglandin F2α receptors within primate luteal cells.
    Authors: Kim Et al.
    Reproduction  2015;149:453
  31. Anti-estrogen Resistance in Human Breast Tumors Is Driven by JAG1-NOTCH4-Dependent Cancer Stem Cell Activity.
    Authors: Simões Et al.
    Cell Cycle  2015;12:1968
  32. Effects of Atrazine on Estrogen Receptor α- and G Protein-Coupled Receptor 30-Mediated Signaling and Proliferation in Cancer Cells and Cancer-Associated Fibroblasts.
    Authors: Albanito Et al.
    Environ Health Perspect  2015;123:493
  33. Antiapoptotic factor humanin is expressed in normal and tumoral pituitary cells and protects them from TNF-α-induced apoptosis.
    Authors: Gottardo Et al.
    PLoS One  2014;9:e111548
  34. Comprehensive analysis of prostaglandin metabolic enzyme expression during pregnancy and the characterization of AKR1B1 as a prostaglandin F synthase at the maternal-conceptus interface in pigs.
    Authors: Seo Et al.
    Breast Cancer Res  2014;90:99
  35. Effects of Estetrol on Migration and Invasion in T47-D Breast Cancer Cells through the Actin Cytoskeleton.
    Authors: Giretti Et al.
    Front Endocrinol (Lausanne)  2014;5:80
  36. Functional analysis of MKP-1 and MKP-2 in breast cancer tamoxifen sensitivity.
    Authors: Haagenson Et al.
    Oncotarget  2014;5:1101
  37. Inhibition of c-Src blocks oestrogen-induced apoptosis and restores oestrogen-stimulated growth in long-term oestrogen-deprived breast cancer cells.
    Authors: Fan Et al.
    Eur J Cancer  2014;50:457
  38. A molecular model for the mechanism of acquired tamoxifen resistance in breast cancer.
    Authors: Fan Et al.
    Eur J Cancer  2014;50:2866
  39. Anti-tumor efficacy of fulvestrant in estrogen receptor positive gastric cancer.
    Authors: Yi Et al.
    Sci Rep  2014;4:7592
  40. β-D-glucan inhibits endocrine-resistant breast cancer cell proliferation and alters gene expression.
    Authors: Jafaar Et al.
    Int J Oncol  2014;44:1365
  41. Oestrogen upregulates the sarcoplasmic reticulum Ca(2+) ATPase pump in coronary arteries.
    Authors: Hill and Muldrew
    Clin Exp Pharmacol Physiol  2014;41:430
  42. Egr1 protein acts downstream of estrogen-leukemia inhibitory factor (LIF)-STAT3 pathway and plays a role during implantation through targeting Wnt4.
    Authors: Liang Et al.
    J Biol Chem  2014;289:23534
  43. Activation of a Gq-coupled membrane estrogen receptor rapidly attenuates α2-adrenoceptor-induced antinociception via an ERK I/II-dependent, non-genomic mechanism in the female rat.
    Authors: Nag and Mokha
    Am J Physiol Regul Integr Comp Physiol  2014;267:122
  44. Suppression of autophagic activation in the mouse uterus by estrogen and progesterone.
    Authors: Choi Et al.
    Cell Rep  2014;221:39
  45. Hormonal regulation of epithelial organization in a three-dimensional breast tissue culture model.
    Authors: Speroni Et al.
    PLoS One  2014;20:42
  46. In vitro chronic administration of ERbeta selective ligands and prostate cancer cell growth: hypotheses on the selective role of 3beta-adiol in AR-positive RV1 cells.
    Authors: Colciago Et al.
    Biomed Res Int  2014;2014:801473
  47. Selective inhibition of RET mediated cell proliferation in vitro by the kinase inhibitor SPP86.
    Authors: Alao Et al.
    BMC Cancer  2014;14:853
  48. Breast tumor specific mutation in GATA3 affects physiological mechanisms regulating transcription factor turnover.
    Authors: Adomas Et al.
    BMC Cancer  2014;14:278
  49. Estradiol increases cAMP in the oviductal secretory cells through a nongenomic mechanism.
    Authors: Oróstica Et al.
    Reproduction  2014;148:285
  50. Estrogen receptor-α signaling and localization regulates autophagy and unfolded protein response activation in ER+ breast cancer.
    Authors: Cook and Clarke
    Steroids  2014;1
  51. GDNF-RET signaling in ER-positive breast cancers is a key determinant of response and resistance to aromatase inhibitors.
    Authors: Morandi Et al.
    Cancer Res  2013;73:3783
  52. Gender differences in brain susceptibility to oxidative stress are mediated by levels of paraoxonase-2 expression.
    Authors: Giordano Et al.
    Free Radic Biol Med  2013;58:98
  53. Expression of the aryl hydrocarbon receptor is not required for the proliferation, migration, invasion, or estrogen-dependent tumorigenesis of MCF-7 breast cancer cells.
    Authors: Spink Et al.
    Mol Carcinog  2013;52:544
  54. Retinoic acid receptor alpha is associated with tamoxifen resistance in breast cancer.
    Authors: Johansson Et al.
    Nat Commun  2013;4:2175
  55. Induction of hepatic multidrug resistance-associated protein 3 by ethynylestradiol is independent of cholestasis and mediated by estrogen receptor.
    Authors: Ruiz Et al.
    Proc Natl Acad Sci U S A  2013;41:275
  56. The membrane estrogen receptor ligand STX rapidly enhances GABAergic signaling in NPY/AgRP neurons: role in mediating the anorexigenic effects of 17β-estradiol.
    Authors: Smith Et al.
    Am J Physiol Endocrinol Metab  2013;305:E632
  57. ERβ-dependent effects on uterine endothelial cells are cell specific and mediated via Sp1.
    Authors: Greaves Et al.
    Hum Reprod  2013;28:2490
  58. The effect of estrogen compounds on human embryoid bodies.
    Authors: Kim Et al.
    Proc Natl Acad Sci U S A  2013;20:661
  59. Oestradiol signalling through the Akt-mTORC1-S6K1.
    Authors: Varea Et al.
    Biochim Biophys Acta  2013;1833:1052
  60. Amphiregulin mediates progesterone-induced mammary ductal development during puberty.
    Authors: Aupperlee Et al.
    J Neurosci  2013;15:R44
  61. Estradiol promotes the development of a fibrotic phenotype and is increased in the serum of patients with systemic sclerosis.
    Authors: Aida-Yasuoka Et al.
    J Neurosci  2013;15:R10
  62. Fulvestrant regulates epidermal growth factor (EGF) family ligands to activate EGF receptor (EGFR) signaling in breast cancer cells.
    Authors: Zhang Et al.
    Environ Health Perspect  2013;139:351
  63. Differential action of monohydroxylated polycyclic aromatic hydrocarbons with estrogen receptors α and β.
    Authors: Sievers Et al.
    Proc Natl Acad Sci U S A  2013;132:359
  64. Endocrine disruptors fludioxonil and fenhexamid stimulate miR-21 expression in breast cancer cells.
    Authors: Teng Et al.
    Toxicol Sci  2013;131:71
  65. 17β-Estradiol-induced interaction of ERα with NPPA regulates gene expression in cardiomyocytes.
    Authors: Mahmoodzadeh Et al.
    Cardiovasc Res  2012;96:411
  66. Modulation of ovine SBD-1 expression by 17beta-estradiol in ovine oviduct epithelial cells.
    Authors: Wen Et al.
    BMC Vet Res  2012;8:143
  67. Bisphenol A inhibits follicle growth and induces atresia in cultured mouse antral follicles independently of the genomic estrogenic pathway.
    Authors: Peretz Et al.
    Biol Reprod  2012;87:63
  68. p130Cas over-expression impairs mammary branching morphogenesis in response to estrogen and EGF.
    Authors: Leal Et al.
    PLoS One  2012;7:e49817
  69. The DEK oncogene is a target of steroid hormone receptor signaling in breast cancer.
    Authors: Vinnedge Et al.
    Neuroscience  2012;7:e46985
  70. Screening estrogenic activities of chemicals or mixtures in vivo using transgenic (cyp19a1b-GFP) zebrafish embryos.
    Authors: Brion Et al.
    PLoS One  2012;7:e36069
  71. Insulinotropic effect of the non-steroidal compound STX in pancreatic β-cells.
    Authors: Ropero Et al.
    PLoS One  2012;7:e34650
  72. Estrogen prevents oxidative damage to the mitochondria in Friedreich's ataxia skin fibroblasts.
    Authors: Richardson Et al.
    Endocrinology  2012;7:e34600
  73. Estrogen receptor β dependent attenuation of cytokine-induced cyclooxygenase-2 by androgens in human brain vascular smooth muscle cells and rat mesenteric arteries.
    Authors: Zuloaga Et al.
    Exp Neurol  2012;77:835
  74. Glucose-regulated protein 78 controls cross-talk between apoptosis and autophagy to determine antiestrogen responsiveness.
    Authors: Cook Et al.
    Int J Mol Sci  2012;72:3337
  75. Pre-B cell to macrophage transdifferentiation without significant promoter DNA methylation changes.
    Authors: Rodriguez-Ubreva Et al.
    Nucleic Acids Res  2012;40:1954
  76. Estrogen receptor is activated by korean red ginseng in vitro but not in vivo.
    Authors: Shim and Lee
    J Ginseng Res  2012;36:169
  77. Estrogen-responsive nitroso-proteome in uterine artery endothelial cells: role of endothelial nitric oxide synthase and estrogen receptor-β.
    Authors: Zhang Et al.
    J Cell Physiol  2012;227:146
  78. Activation of Estrogen Receptor by Bavachin from Psoralea corylifolia.
    Authors: Park Et al.
    Proc Natl Acad Sci U S A  2012;20:183
  79. MGMT inhibition restores ERα functional sensitivity to antiestrogen therapy.
    Authors: Bobustuc Et al.
    Mol Med  2012;18:913
  80. Estradiol increases cell growth in human astrocytoma cell lines through ERα activation and its interaction with SRC-1 and SRC-3 coactivators.
    Authors: González-Arenas Et al.
    Biochim Biophys Acta  2012;1823:379
  81. Effects of gonadal hormones on the peripheral cannabinoid receptor 1 (CB1R) system under a myositis condition in rats.
    Authors: Niu Et al.
    J Cereb Blood Flow Metab  2012;153:2283
  82. Estradiol directly attenuates sodium currents and depolarizing afterpotentials in isolated gonadotropin-releasing hormone neurons.
    Authors: Wang and Kuehl-Kovarik
    Brain Res  2012;1436:81
  83. Genistein prevents hyperglycemia-induced monocyte adhesion to human aortic endothelial cells through preservation of the cAMP signaling pathway and ameliorates vascular inflammation in obese diabetic mice.
    Authors: Babu Et al.
    J Nutr  2012;142:724
  84. Estrogen receptor β activation is antinociceptive in a model of visceral pain in the rat.
    Authors: Cao Et al.
    J Pain  2012;13:685
  85. Inhibition of p38-MAPK alters SRC coactivation and estrogen receptor phosphorylation.
    Authors: Antoon Et al.
    Cancer Biol Ther  2012;13:1026
  86. Antiestrogenic activity of flavonoid phytochemicals mediated via the c-Jun N-terminal protein kinase pathway. Cell-type specific regulation of estrogen receptor alpha.
    Authors: Collins-Burow Et al.
    J Steroid Biochem Mol Biol  2012;132:186
  87. Estrogen-like activity of aqueous extract from Agrimonia pilosa Ledeb. in MCF-7 cells.
    Authors: Lee Et al.
    Endocrinology  2012;12:260
  88. Inhibition of XO or NOX attenuates diethylstilbestrol-induced endothelial nitric oxide deficiency without affecting its effects on LNCaP cell invasion and apoptosis.
    Authors: Youn Et al.
    Clin Sci (Lond)  2012;123:509
  89. Estrogen receptor β (ERβ) produces autophagy and necroptosis in human seminoma cell line through the binding of the Sp1 on the phosphatase and tensin homolog deleted from chromosome 10 (PTEN) promoter gene.
    Authors: Guido Et al.
    Int J Clin Exp Pathol  2012;11:2911
  90. 17β-Estradiol enhances breast cancer cell motility and invasion via extra-nuclear activation of actin-binding protein ezrin.
    Authors: Zheng Et al.
    PLoS One  2011;6:e22439
  91. mTOR controls ovarian follicle growth by regulating granulosa cell proliferation.
    Authors: Yu Et al.
    PLoS One  2011;6:e21415
  92. Daidzein prevents the increase in CD4+CD28null T cells and B lymphopoesis in ovariectomized mice: a key mechanism for anti-osteoclastogenic effect.
    Authors: Tyagi Et al.
    PLoS One  2011;6:e21216
  93. The effect of 17β-estradiol on cholesterol content in human macrophages is influenced by the lipoprotein milieu.
    Authors: Corcoran Et al.
    Clin Cancer Res  2011;47:109
  94. Complete estrogen receptor blocker ICI182,780 promotes the proliferation of vascular smooth muscle cells.
    Authors: He Et al.
    Acta Biochim Biophys Sin (Shanghai)  2011;43:118
  95. Selective mutations in estrogen receptor alpha D-domain alters nuclear translocation and non-estrogen response element gene regulatory mechanisms.
    Authors: Burns Et al.
    J Biol Chem  2011;286:12640
  96. Tamoxifen increases nuclear respiratory factor 1 transcription by activating estrogen receptor beta and AP-1 recruitment to adjacent promoter binding sites.
    Authors: Ivanova Et al.
    FASEB J  2011;25:1402
  97. The liver receptor homolog-1 (LRH-1) is expressed in human islets and protects {β}-cells against stress-induced apoptosis.
    Authors: Baquié Et al.
    FEMS Immunol Med Microbiol  2011;20:2823
  98. JNK suppression is essential for 17β-Estradiol inhibits prostaglandin E2-Induced uPA and MMP-9 expressions and cell migration in human LoVo colon cancer cells.
    Authors: Hsu Et al.
    J Vet Sci  2011;18:61
  99. Therapeutically activating RB: reestablishing cell cycle control in endocrine therapy-resistant breast cancer.
    Authors: Thangavel Et al.
    Endocr Relat Cancer  2011;18:333
  100. Expression and regulation of Enpp2 in rat uterus during the estrous cycle.
    Authors: Ahn Et al.
    Toxicol Sci  2011;12:379
  101. 17beta-Estradiol inhibits matrix metalloproteinase-2 transcription via MAP kinase in fibroblasts.
    Authors: Mahmoodzadeh Et al.
    Cardiovasc Res  2010;85:719
  102. Developmental exposures of male rats to soy isoflavones impact Leydig cell differentiation.
    Authors: Sherrill Et al.
    Biol Reprod  2010;83:488
  103. Interdependence of platelet-derived growth factor and estrogen-signaling pathways in inducing neonatal rat testicular gonocytes proliferation.
    Authors: Thuillier Et al.
    Biol Reprod  2010;82:825
  104. Hepatocyte growth factor system in the mouse uterus: variation across the estrous cycle and regulation by 17-β-estradiol and progesterone.
    Authors: Zhang
    Clin Cancer Res  2010;82:1037
  105. BRD7, a subunit of SWI/SNF complexes, binds directly to BRCA1 and regulates BRCA1-dependent transcription.
    Authors: Harte Et al.
    Cancer Res  2010;70:2538
  106. Estrogen suppresses MLK3-mediated apoptosis sensitivity in ER+ breast cancer cells.
    Authors: Rangasamy Et al.
    Cancer Res  2010;70:1731
  107. Extranuclear estrogen receptors mediate the neuroprotective effects of estrogen in the rat hippocampus.
    Authors: Yang Et al.
    PLoS One  2010;5:e9851
  108. Cell cycle and anti-estrogen effects synergize to regulate cell proliferation and ER target gene expression.
    Authors: Dalvai and Bystricky
    PLoS One  2010;5:e11011
  109. Estradiol selectively stimulates endothelial prostacyclin production through estrogen receptor-{alpha}.
    Authors: Sobrino Et al.
    J Mol Endocrinol  2010;44:237
  110. Estrogen-receptor-mediated protection of cerebral endothelial cell viability and mitochondrial function after ischemic insult in vitro.
    Authors: Guo Et al.
    PLoS One  2010;30:545
  111. c-Jun activation is required for 4-hydroxytamoxifen-induced cell death in breast cancer cells.
    Authors: Madeo Et al.
    Oncogene  2010;29:978
  112. Estrogen receptor α (ERα) mediates 17β-estradiol (E2)-activated expression of HBO1.
    Authors: Wang Et al.
    Proc Natl Acad Sci U S A  2010;29:140
  113. 5-HT(1A), SST(1), and SST(2) receptors mediate inhibitory postsynaptic potentials in the submucous plexus of the guinea pig ileum.
    Authors: Foong Et al.
    Receptors Clin Investig  2010;298:G384
  114. Bisphenol A and estradiol are equipotent in antagonizing cisplatin-induced cytotoxicity in breast cancer cells.
    Authors: LaPensee Et al.
    Cancer Res  2010;290:167
  115. Mechano-transduction in osteoblastic cells involves strain-regulated estrogen receptor alpha-mediated control of insulin-like growth factor (IGF) I receptor sensitivity to Ambient IGF, leading to phosphatidylinositol 3-kinase/AKT-dependent Wnt/LRP5 recept
    Authors: Sunters Et al.
    J Biol Chem  2010;285:8743
  116. Androgen receptor-dependent transactivation of growth arrest-specific gene 6 mediates inhibitory effects of testosterone on vascular calcification.
    Authors: Son Et al.
    J Biol Chem  2010;285:7537
  117. Proinflammatory cytokines enhance estrogen-dependent expression of the multidrug transporter gene ABCG2 through estrogen receptor and NF{kappa}B cooperativity at adjacent response elements.
    Authors: Pradhan Et al.
    J Biol Chem  2010;285:31100
  118. Down-regulation of PROS1 gene expression by 17beta-estradiol via estrogen receptor alpha (ERalpha)-Sp1 interaction recruiting receptor-interacting protein 140 and the corepressor-HDAC3 complex.
    Authors: Suzuki Et al.
    J Biol Chem  2010;285:13444
  119. Estrogen receptor-alpha promotes breast cancer cell motility and invasion via focal adhesion kinase and N-WASP.
    Authors: Sanchez Et al.
    Mol Endocrinol  2010;24:2114
  120. Unexpected hormonal activity of a catechol equine estrogen metabolite reveals reversible glutathione conjugation.
    Authors: Peng Et al.
    Chem Res Toxicol  2010;23:1374
  121. Roles of 17β-estradiol involve regulation of reelin expression and synaptogenesis in the dentate gyrus.
    Authors: Bender Et al.
    Cereb Cortex  2010;20:2985
  122. Proliferation of human mammary cancer cells exposed to 27-hydroxycholesterol.
    Authors: Cruz Et al.
    J Expo Sci Environ Epidemiol  2010;1:531
  123. B7-H1-dependent sex-related differences in tumor immunity and immunotherapy responses.
    Authors: Lin Et al.
    J Immunol  2010;185:2747
  124. Estradiol suppresses NF-kappa B activation through coordinated regulation of let-7a and miR-125b in primary human macrophages.
    Authors: Murphy Et al.
    J Immunol  2010;184:5029
  125. Prolactin and oestrogen synergistically regulate gene expression and proliferation of breast cancer cells.
    Authors: Rasmussen Et al.
    Endocr Relat Cancer  2010;17:809
  126. Progesterone increases systemic and local uterine proportions of CD4+CD25+ Treg cells during midterm pregnancy in mice.
    Authors: Mao Et al.
    Endocrinology  2010;151:5477
  127. Antiestrogenic effects of the novel sphingosine kinase-2 inhibitor ABC294640.
    Authors: Antoon Et al.
    Endocrinology  2010;151:5124
  128. Estrogen stimulates proliferation and differentiation of neural stem/progenitor cells through different signal transduction pathways.
    Authors: Okada Et al.
    Am J Physiol Heart Circ Physiol  2010;11:4114
  129. Bisphenol A impairs the double-strand break repair machinery in the germline and causes chromosome abnormalities.
    Authors: Allard and Colaiácovo
    Proc Natl Acad Sci U S A  2010;107:20405
  130. Autocrine regulation of cell proliferation by estrogen receptor-alpha in estrogen receptor-alpha-positive breast cancer cell lines.
    Authors: Tan Et al.
    BMC Cancer  2009;9:31
  131. Blockade of estrogen action upregulates estrogen receptor-alpha mRNA in the fetal brain.
    Authors: Schaub and Wood
    Neonatology  2009;96:115
  132. Effects of 17beta-oestradiol on rat detrusor smooth muscle contractility.
    Authors: Valeri Et al.
    Exp Physiol  2009;94:834
  133. The estrogen receptor alpha pathway induces oncogenic Wip1 phosphatase gene expression.
    Authors: Han Et al.
    Mol Cancer Res  2009;7:713
  134. Tamoxifen inhibits TRPV6 activity via estrogen receptor-independent pathways in TRPV6-expressing MCF-7 breast cancer cells.
    Authors: Bolanz Et al.
    Mol Cancer Res  2009;7:2000
  135. Characterization of a novel small molecule subtype specific estrogen-related receptor alpha antagonist in MCF-7 breast cancer cells.
    Authors: Chisamore Et al.
    PLoS One  2009;4:e5624
  136. Estradiol stimulates Akt, AMP-activated protein kinase (AMPK) and TBC1D1/4, but not glucose uptake in rat soleus.
    Authors: Rogers Et al.
    Biochem Biophys Res Commun  2009;382:646
  137. The oxysterol receptor LXR inhibits proliferation of human breast cancer cells.
    Authors: Vedin Et al.
    Cancer Res  2009;30:575
  138. CRK7 modifies the MAPK pathway and influences the response to endocrine therapy.
    Authors: Iorns Et al.
    Carcinogenesis  2009;30:1696
  139. Estradiol-induced estrogen receptor-α trafficking.
    Authors: Bondar Et al.
    Mol Cell Endocrinol  2009;29:15323
  140. Cytoskeletal changes underlie estrogen's acute effects on synaptic transmission and plasticity.
    Authors: Kramár Et al.
    Hum Mol Genet  2009;29:12982
  141. K+-dependent Na+/Ca2+ exchanger 3 is involved in renal active calcium transport and is differentially expressed in the mouse kidney.
    Authors: Lee Et al.
    Am J Physiol Renal Physiol  2009;297:F371
  142. A novel mechanism of natural vitamin E tocotrienol activity: involvement of ERbeta signal transduction.
    Authors: Comitato Et al.
    Am J Physiol Endocrinol Metab  2009;297:E427
  143. Mutational analysis of progesterone receptor functional domains in stable cell lines delineates sets of genes regulated by different mechanisms.
    Authors: Quiles Et al.
    Mol Endocrinol  2009;23:809
  144. Cell death mechanisms in GT1-7 GnRH cells exposed to polychlorinated biphenyls PCB74, PCB118, and PCB153.
    Authors: Dickerson Et al.
    Toxicol Appl Pharmacol  2009;237:237
  145. Mechanism of the salutary effects of estrogen on kupffer cell phagocytic capacity following trauma-hemorrhage: pivotal role of Akt activation.
    Authors: Hsieh Et al.
    J Immunol  2009;182:4406
  146. Differential actions of estrogen and SERMs in regulation of the actin cytoskeleton of endometrial cells.
    Authors: Flamini Et al.
    Mol Hum Reprod  2009;15:675
  147. Soy phytoestrogens are neuroprotective against stroke-like injury in vitro.
    Authors: Schreihofer and Redmond
    Neuroscience  2009;158:602
  148. 17Beta-estradiol at low concentrations acts through distinct pathways in normal versus benign prostatic hyperplasia-derived prostate stromal cells.
    Authors: Park Et al.
    Endocrinology  2009;150:4594
  149. Identification of the potent phytoestrogen glycinol in elicited soybean (Glycine max).
    Authors: Boue Et al.
    Endocrinology  2009;150:2446
  150. Blockade of estrogen receptor signaling inhibits growth and migration of medulloblastoma.
    Authors: Belcher Et al.
    Endocrinology  2009;150:1112
  151. Hes-6, an inhibitor of Hes-1, is regulated by 17β-estradiol and promotes breast cancer cell proliferation.
    Authors: Hartman Et al.
    Arthritis Res Ther  2009;11:R79
  152. Characterization of housekeeping genes in zebrafish: male-female differences and effects of tissue type, developmental stage and chemical treatment.
    Authors: McCurley and Callard
    BMC Mol Biol  2008;9:102
  153. Estrogen determines sex differences in airway responsiveness after allergen exposure.
    Authors: Matsubara Et al.
    Reprod Sci  2008;38:501
  154. Estrogen prevents intestinal inflammation after trauma-hemorrhage via downregulation of angiotensin II and angiotensin II subtype I receptor.
    Authors: Chen Et al.
    J Mol Endocrinol  2008;295:G1131
  155. Genomic deletion of estrogen receptors ERalpha and ERbeta does not alter estrogen-mediated inhibition of Ca2+ influx and contraction in murine cardiomyocytes.
    Authors: Ullrich Et al.
    Am J Physiol Heart Circ Physiol  2008;294:H2421
  156. Tyrosine phosphorylation of the nuclear receptor coactivator AIB1/SRC-3 is enhanced by Abl kinase and is required for its activity in cancer cells.
    Authors: Oh Et al.
    Mol Cell Biol  2008;28:6580
  157. Progesterone induction of the 11beta-hydroxysteroid dehydrogenase type 2 promoter in breast cancer cells involves coordinated recruitment of STAT5A and progesterone receptor to a distal enhancer and polymerase tracking.
    Authors: Subtil-Rodríguez Et al.
    Mol Cell Biol  2008;28:3830
  158. Hormonal regulation of BCRP expression in human placental BeWo cells.
    Authors: Wang Et al.
    Pharm Res  2008;25:444
  159. Differential regulation of the inducible nitric oxide synthase gene by estrogen receptors 1 and 2.
    Authors: Tsutsumi Et al.
    Tissue Eng Part C Methods  2008;199:267
  160. The expression and ovarian steroid regulation of endometrial micro-RNAs.
    Authors: Toloubeydokhti Et al.
    J Exp Clin Cancer Res  2008;15:993
  161. Roles of estrogen receptor alpha and beta in modulating urothelial cell proliferation.
    Authors: Teng Et al.
    Endocr Relat Cancer  2008;15:351
  162. Effects of estradiol and progesterone on the proinflammatory cytokine production by mononuclear cells from patients with chronic hepatitis C.
    Authors: Yuan Et al.
    World J Gastroenterol  2008;14:2200
  163. Estrogen-enhanced gene expression of lipoprotein lipase in heart is antagonized by progesterone.
    Authors: Liu Et al.
    Endocrinology  2008;149:711
  164. The novel estrogen receptor, G protein-coupled receptor 30, mediates the proliferative effects induced by 17β-estradiol on mouse spermatogonial GC-1 cell line.
    Authors: Sirianni Et al.
    Int J Oncol  2008;149:5043
  165. The nutritional flavanone naringenin triggers antiestrogenic effects by regulating estrogen receptor alpha-palmitoylation.
    Authors: Galluzzo Et al.
    Endocrinology  2008;149:2567
  166. Identification of CDK10 as an important determinant of resistance to endocrine therapy for breast cancer.
    Authors: Iorns Et al.
    Cancer Cell  2008;13:91
  167. Genistein, a soy phytoestrogen, upregulates the expression of human endothelial nitric oxide synthase and lowers blood pressure in spontaneously hypertensive rats.
    Authors: Si and Liu
    J Nutr  2008;138:297
  168. Differential expression of microRNAs in myometrium and leiomyomas and regulation by ovarian steroids.
    Authors: Pan Et al.
    J Biol Chem  2008;12:227
  169. G-protein-coupled receptor 30 and estrogen receptor-alpha are involved in the proliferative effects induced by atrazine in ovarian cancer cells.
    Authors: Albanito Et al.
    Environ Health Perspect  2008;116:1648
  170. Estrogen receptor independent neurotoxic mechanism of bisphenol A, an environmental estrogen.
    Authors: Lee Et al.
    J Vet Sci  2007;8:27
  171. Blockade of estrogen receptors decreases CNS and pituitary prostaglandin synthase expression in fetal sheep.
    Authors: Schaub Et al.
    FASEB J  2007;87:121
  172. Genistein chemoprevention of prostate cancer in TRAMP mice.
    Authors: Wang Et al.
    J Carcinog  2007;6:3
  173. Definition of functionally important mechanistic differences among selective estrogen receptor down-regulators.
    Authors: Wittmann Et al.
    Cancer Res  2007;67:9549
  174. G protein-coupled receptor 30 (GPR30) mediates gene expression changes and growth response to 17beta-estradiol and selective GPR30 ligand G-1 in ovarian cancer cells.
    Authors: Albanito Et al.
    Cancer Res  2007;67:1859
  175. NM23-H2, an estrogen receptor β-associated protein, shows diminished expression with progression of atherosclerosis.
    Authors: Rayner Et al.
    Reprod Sci  2007;292:R743
  176. Regulation of GREB1 transcription by estrogen receptor α through a multipartite enhancer spread over 20 kb of upstream flanking sequences.
    Authors: Deschênes Et al.
    BMC Complement Altern Med  2007;282:17335
  177. The silencing mediator of retinoic acid and thyroid hormone receptor (SMRT) corepressor is required for full estrogen receptor alpha transcriptional activity.
    Authors: Peterson Et al.
    Mol Cell Biol  2007;27:5933
  178. Estrogen regulates Bcl-w and Bim expression: role in protection against beta-amyloid peptide-induced neuronal death.
    Authors: Yao Et al.
    J Neurosci  2007;27:1422
  179. 17β-Estradiol utilizes the estrogen receptor to regulate CD16 expression in monocytes.
    Authors: Kramer Et al.
    Stroke  2007;279:16
  180. Kruppel-like factor 9 is a negative regulator of ligand-dependent estrogen receptor alpha signaling in Ishikawa endometrial adenocarcinoma cells.
    Authors: Velarde Et al.
    Mol Endocrinol  2007;21:2988
  181. Modulation of estrogen receptor α protein level and survival function by DBC-1.
    Authors: Trauernicht Et al.
    Br J Pharmacol  2007;21:1526
  182. Neuroprotection by estrogen against MPP+-induced dopamine neuron death is mediated by ERα in primary cultures of mouse mesencephalon.
    Authors: Bains Et al.
    Biol Reprod  2007;204:767
  183. Resveratrol inhibits expression and binding activity of the monocyte chemotactic protein-1 receptor, CCR2, on THP-1 monocytes.
    Authors: Cullen Et al.
    Atherosclerosis  2007;195:e125
  184. Activation of estrogen receptor-mediated gene transcription by the equine estrogen metabolite, 4-methoxyequilenin, in human breast cancer cells.
    Authors: Chang Et al.
    Endocrinology  2007;148:4793
  185. Exposure to phytoestrogens in the perinatal period affects androgen secretion by testicular Leydig cells in the adult rat.
    Authors: Akingbemi Et al.
    Endocrinology  2007;148:4475
  186. MAPK signaling is critical to estradiol protection of CA1 neurons in global ischemia.
    Authors: Jover-Mengual Et al.
    Endocrinology  2007;148:1131
  187. Reversal of the estrogen receptor negative phenotype in breast cancer and restoration of antiestrogen response.
    Authors: Bayliss Et al.
    Clin Cancer Res  2007;13:7029
  188. Estradiol-17beta regulates mouse uterine epithelial cell proliferation through insulin-like growth factor 1 signaling.
    Authors: Zhu and Pollard
    Proc Natl Acad Sci U S A  2007;104:15847
  189. Additive growth inhibitory effects of ibandronate and antiestrogens in estrogen receptor-positive breast cancer cell lines.
    Authors: Journé Et al.
    Cancer Res  2006;8:R2
  190. Farnesyl-transferase inhibitor R115,777 enhances tamoxifen inhibition of MCF-7 cell growth through estrogen receptor dependent and independent pathways.
    Authors: Dalenc Et al.
    Breast Cancer Res  2006;7:R1159
  191. Royal jelly stimulates bone formation: physiologic and nutrigenomic studies with mice and cell lines.
    Authors: Narita Et al.
    Biosci Biotechnol Biochem  2006;70:2508
  192. 17beta-estradiol, genistein, and 4-hydroxytamoxifen induce the proliferation of thyroid cancer cells through the g protein-coupled receptor GPR30.
    Authors: Vivacqua Et al.
    Mol Pharmacol  2006;70:1414
  193. Estrogens, selective estrogen receptor modulators, and a selective estrogen receptor down-regulator inhibit endothelial production of tissue factor pathway inhibitor 1.
    Authors: Dahm Et al.
    BMC Cardiovasc Disord  2006;6:40
  194. Cyclin D1 is necessary for tamoxifen-induced cell cycle progression in human breast cancer cells.
    Authors: Kilker and Planas-Silva
    Breast Cancer Res  2006;66:11478
  195. Efficient intracellular multiplication of Legionella pneumophila in human monocytes requires functional host cell L-type calcium channels.
    Authors: Wieland Et al.
    Am J Physiol Gastrointest Liver Physiol  2006;47:296
  196. 17β-Estradiol inhibits subarachnoid hemorrhage-induced inducible nitric oxide synthase gene expression by interfering with the nuclear factor κ B transactivation.
    Authors: Shih Et al.
    Proc Natl Acad Sci U S A  2006;37:3025
  197. Convergent transcriptional profiles induced by endogenous estrogen and distinct xenoestrogens in breast cancer cells.
    Authors: Buterin Et al.
    Carcinogenesis  2006;27:1567
  198. Antiestrogens and the formation of DNA damage in rats: a comparison.
    Authors: Kim Et al.
    Infect Immun  2006;19:852
  199. The hop phytoestrogen, 8-prenylnaringenin, reverses the ovariectomy-induced rise in skin temperature in an animal model of menopausal hot flushes.
    Authors: Bowe Et al.
    J Endocrinol  2006;191:399
  200. Tamoxifen dilates porcine coronary arteries: roles for nitric oxide and ouabain-sensitive mechanisms.
    Authors: Leung Et al.
    Br J Pharmacol  2006;149:703
  201. Activation of insulin-like growth factor I receptor-mediated pathway by ginsenoside Rg1.
    Authors: Chen Et al.
    Br J Pharmacol  2006;147:542
  202. Biological role of estrogen receptor β in salivary gland adenocarcinoma cells.
    Authors: Ohshiro Et al.
    Exp Ther Med  2006;12:5994
  203. The estrogenic effect of bisphenol A disrupts pancreatic β-cell function in vivo and induces insulin resistance.
    Authors: Alonso-Magdalena Et al.
    Am J Physiol Gastrointest Liver Physiol  2006;114:106
  204. Disruption of estrogen receptor DNA-binding domain and related intramolecular communication restores tamoxifen sensitivity in resistant breast cancer.
    Authors: Wang Et al.
    BMC Immunol  2006;10:487
  205. A model of acquired autoresistance to a potent ErbB2 tyrosine kinase inhibitor and a therapeutic strategy to prevent its onset in breast cancer.
    Authors: Xia Et al.
    Br J Cancer  2006;103:7795
  206. An inherent role of microtubule network in the action of nuclear receptor.
    Authors: Manavathi Et al.
    J Endocrinol  2006;103:15981
  207. Estrogen receptor signaling protects against immune suppression by UV radiation exposure.
    Authors: Widyarini Et al.
    Neuroendocrinology  2006;103:12837
  208. Estrogen receptor alpha pathway is involved in the regulation of Calbindin-D9k in the uterus of immature rats.
    Authors: Lee Et al.
    Toxicol Sci  2005;84:270
  209. Membrane estrogen receptor-alpha levels predict estrogen-induced ERK1/2 activation in MCF-7 cells.
    Authors: Zivadinovic and Watson
    Breast Cancer Res  2005;7:R130
  210. Effects of estradiol on lipopolysaccharide and Pam3Cys stimulation of CCL20/macrophage inflammatory protein 3 α and tumor necrosis factor α production by uterine epithelial cells in culture.
    Authors: Crane-Godreau and Wira
    Breast Cancer Res Treat  2005;73:4231
  211. Gonadal steroids differentially modulate neurotoxicity of HIV and cocaine: testosterone and ICI 182,780 sensitive mechanism.
    Authors: Kendall Et al.
    BMC Neurosci  2005;6:40
  212. Estren promotes androgen phenotypes in primary lymphoid organs and submandibular glands.
    Authors: Islander Et al.
    Reprod Nutr Dev  2005;6:16
  213. Estrogen increases mitochondrial efficiency and reduces oxidative stress in cerebral blood vessels.
    Authors: Stirone Et al.
    Mol Pharmacol  2005;68:959
  214. Regulation of endogenous gene expression in human non-small cell lung cancer cells by estrogen receptor ligands.
    Authors: Hershberger Et al.
    Cancer Cell  2005;65:1598
  215. The effects of dietary phytoestrogens on aromatase activity in human endometrial stromal cells.
    Authors: Edmunds Et al.
    Environ Health Perspect  2005;45:709
  216. Formation of an IKKalpha-dependent transcription complex is required for estrogen receptor-mediated gene activation.
    Authors: Park Et al.
    Mol Cell  2005;18:71
  217. Palmitoylation-dependent estrogen receptor alpha membrane localization: regulation by 17beta-estradiol.
    Authors: Acconcia Et al.
    Mol Biol Cell  2005;16:231
  218. Progesterone antagonizes the permissive action of estradiol on tumor necrosis factor-α-induced apoptosis of anterior pituitary cells.
    Authors: Candolfi Et al.
    Proc Natl Acad Sci U S A  2005;146:736
  219. Firing pattern and rapid modulation of activity by estrogen in primate luteinizing hormone releasing hormone-1 neurons.
    Authors: Abe and Terasawa
    Endocrinology  2005;146:4312
  220. Estrogen modulates endothelial and neuronal nitric oxide synthase expression via an estrogen receptor beta-dependent mechanism in hypothalamic slice cultures.
    Authors: Gingerich and Krukoff
    Endocrinology  2005;146:2933
  221. Estrogenic effects of two derivatives of icariin on human breast cancer MCF-7 cells.
    Authors: Ye and Lou
    Phytomedicine  2005;12:735
  222. Identification of target genes in breast cancer cells directly regulated by the SRC-3/AIB1 coactivator.
    Authors: Labhart Et al.
    Proc Natl Acad Sci U S A  2005;102:1339
  223. Steroid-free medium discloses oestrogenic effects of the bisphosphonate clodronate on breast cancer cells.
    Authors: Journe Et al.
    Breast Cancer Res  2004;91:1703
  224. Tamoxifen and the Rafoxifene analog LY117018: their effects on arachidonic acid release from cells in culture and on prostaglandin I2 production by rat liver cells.
    Authors: Levine
    Proc Natl Acad Sci U S A  2004;4:49
  225. Age-related reduction in estrogen receptor-mediated mechanisms of vascular relaxation in female spontaneously hypertensive rats.
    Authors: Wynne Et al.
    Hypertension  2004;43:405
  226. Wnt/β-catenin and estrogen signaling converge in vivo.
    Authors: Kouzmenko Et al.
    Am J Respir Cell Mol Biol  2004;279:40255
  227. The G protein-coupled receptor GPR30 mediates c-fos up-regulation by 17beta-estradiol and phytoestrogens in breast cancer cells.
    Authors: Maggiolini Et al.
    J Biol Chem  2004;279:27008
  228. Morphological effects of estrogen on cholinergic neurons in vitro involves activation of extracellular signal-regulated kinases.
    Authors: Dominguez Et al.
    Carcinogenesis  2004;24:982
  229. HES-1 inhibits 17β-estradiol and heregulin-β1-mediated upregulation of E2F-1.
    Authors: Hartman Et al.
    J Cell Mol Med  2004;23:8826
  230. Nuclear insulin receptor substrate 1 interacts with estrogen receptor alpha at ERE promoters.
    Authors: Morelli Et al.
    Oncogene  2004;23:7517
  231. Estrogen receptor beta isoforms exhibit differences in ligand-activated transcriptional activity in an estrogen response element sequence-dependent manner.
    Authors: Ramsey Et al.
    Endocrinology  2004;145:149
  232. Xenoestrogen-induced ERK-1 and ERK-2 activation via multiple membrane-initiated signaling pathways.
    Authors: Bulayeva and Watson
    Environ Health Perspect  2004;112:1481
  233. Human epidermal growth factor receptor 2 status modulates subcellular localization of and interaction with estrogen receptor α in breast cancer cells.
    Authors: Yang Et al.
    Oncogene  2004;10:3621
  234. Regulation of PDGF production and ERK activation by estrogen is associated with TSC2 gene expression.
    Authors: Finlay Et al.
    Am J Physiol Cell Physiol  2003;285:C409
  235. The effects of estrogen, its antagonist ICI 182, 780, and interferon-tau on the expression of estrogen receptors and integrin alphaV beta 3 on cycle day 16 in bovine endometrium.
    Authors: Kimmins Et al.
    Reprod Biol Endocrinol  2003;1:38
  236. Inhibition of prolactin (PRL)-induced proliferative signals in breast cancer cells by a molecular mimic of phosphorylated PRL, S179D-PRL.
    Authors: Schroeder Et al.
    Biomol Ther (Seoul)  2003;144:5300
  237. Environmental estrogens alter early development in Xenopus laevis.
    Authors: Bevan Et al.
    J Endocrinol  2003;111:488
  238. Involvement of bone morphogenetic protein 4 (BMP-4) in pituitary prolactinoma pathogenesis through a Smad/estrogen receptor crosstalk.
    Authors: Paez-Pereda Et al.
    BMC Cancer  2003;100:1034
  239. Testosterone attenuates expression of vascular cell adhesion molecule-1 by conversion to estradiol by aromatase in endothelial cells: implications in atherosclerosis.
    Authors: Mukherjee Et al.
    Mol Endocrinol  2002;99:4055
  240. Estradiol reduces F2α-isoprostane production in cultured human endothelial cells.
    Authors: Hermenegildo Et al.
    Biol Reprod  2002;283:H2644
  241. Receptor-mediated ethinylestradiol-induced oxidative DNA damage in rat testicular cells.
    Authors: Wellejus and Loft
    Proc Natl Acad Sci U S A  2002;16:195
  242. 17-β-oestradiol-induced vasorelaxation in vitro is mediated by eNOS through hsp90 and akt/pkb dependent mechanism.
    Authors: Bucci Et al.
    Drug Metab Dispos  2002;135:1695
  243. Estrogen alters thresholds for B cell apoptosis and activation.
    Authors: Grimaldi Et al.
    J Clin Invest  2002;109:1625
  244. The antioxidant neuroprotective effects of estrogens and phenolic compounds are independent from their estrogenic properties.
    Authors: Moosmann and Behl
    Chem Res Toxicol  1999;96:8867
  245. Estrogen receptor (ER) modulators each induce distinct conformational changes in ER α and ER β.
    Authors: Paige Et al.
    J Biomed Sci  1999;96:3999
  246. Estradiol induces the calcium-dependent translocation of endothelial nitric oxide synthase.
    Authors: Goetz Et al.
    J Neurosci  1999;96:2788
  247. High level expression of differentially localized BAG-1 isoforms in some oestrogen receptor-positive human breast cancers.
    Authors: Brimmell Et al.
    Br J Cancer  1999;81:1042
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