ID 8

ID 8 | CAS No. 147591-46-6 | Compounds for Stem Cell Proliferation and Renewal
1 Image
Description: Sustains self-renewal and pluripotency of ESCs

Chemical Name: 1-(4-Methoxyphenyl)-2-methyl-3-nitro-1H-indol-6-ol

Purity: ≥99%

Product Details

Biological Activity

ID 8 is a sustains self-renewal and pluripotency of mouse embryonic stem cells (ESCs) in vitro. Stimulates proliferation at a steady rate (observed in serum-free media supplemented with 10 μM over a 30 day period). Also supports human PSC maintenance in combiantions with Wnt3a. DYRK inhibitor

Technical Data

Soluble to 100 mM in DMSO
Store at +4°C

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Background References

  1. Indole derivatives sustain embryonic stem cell self-renewal in long-term culture.
    Miyabayashi et al.
    Biosci.Biotechnol.Biochem., 2008;72:1242
  2. Controlling destiny through chemistry: small-molecule regulators of cell fate.
    Firestone and Chen
    ACS Chem.Biol., 2009;5:15
  3. Wnt signaling orchestration with a small molecule DYRK inhibitor provides long-term xeno-free human pluripotent cell expansion.
    Hasegawa et al.
    Stem Cells Transl.Med., 2012;1:18

Product Datasheets

Reconstitution Calculator
Molarity Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.


Molarity Calculator


*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).


No product specific FAQs exist for this product, however you may

View all Small Molecule FAQs

Reviews for ID 8

There are currently no reviews for this product. Be the first to review ID 8 and earn rewards!

Have you used ID 8?

Submit a review and receive an Amazon gift card.

$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review
Tocris Bioscience is the leading supplier of novel and exclusive tools for life science research with over 30 years' experience in the industry. Tocris is a Bio-Techne brand.