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Selective p160ROCK inhibitor
Potent, selective inhibitor of TGF-βRI, ALK4 and ALK7
Major endogenous prostanoid
Selective inhibitor of TGF-βRI, ALK4 and ALK7
PORCN inhibitor; inhibits Wnt processing and secretion
Selective inhibitor of p38 MAPK
Prototypical PI 3-kinase inhibitor; also inhibits other kinases
Potent, selective GSK-3 inhibitor
Potent GSK-3 inhibitor; also inhibits cdks
E2F transcription factor inhibitor
Selective PPARγ agonist; antidiabetic agent
Glutamate receptor ligand
Anti-inflammatory; causes mast cell degranulation and histamine release
Broad spectrum ion channel blocker; antiarrhythmic
PCAF/p300 inhibitor; anticancer
Antibiotic; inhibits bacterial type II topoisomerase
Dual ERK1/RasGAP inhibitor. Maintains ESC self-renewal
Enhances survival of human ESCs following enzymatic dissociation
Potent and selective Lck and Src inhibitor; also inhibits SIK
Sustains self-renewal and pluripotency of ESCs
CK1 inhibitor; converts epiblast stem cells to ESCs and promotes ESC self-renewal
Promotes survival of muscle stem cells (MuSCs); MDM2 inhibitor; activates p53 activity
Y-27632 synthesized to cGMP guidelines
SB 431542 synthesized to cGMP guidelines
