Compounds for Stem Cell Proliferation & Renewal: Products

Maintaining stem cells in an undifferentiated state while in culture is important to ensure consistency and reproducibility among experiments. Traditionally, embryonic stem cells have been grown in culture using mouse embryonic fibroblasts as a feeder layer or using defined culture media.

"Compounds for Stem Cell Proliferation and Renewal" has 30 results in Products.
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Y-27632 dihydrochloride 

Selective ROCK inhibitor; inhibits ROCK1 (p160 ROCK) and ROCK2; stem cell freezing (cryopreservation) media component

Y-27632 dihydrochloride 

Y-27632 synthesized to cGMP guidelines

SB 431542 

Potent, selective inhibitor of TGF-βRI, ALK4 and ALK7

SB 431542 

SB 431542 synthesized to cGMP guidelines

A 83-01 

Selective inhibitor of TGF-βRI, ALK4 and ALK7

Prostaglandin E2 

Promotes HSCs expansion; increases HSCs engraftment; also endogenous prostaglandin

IWP 2 

PORCN inhibitor; inhibits Wnt processing and secretion

SB 203580 

Selective inhibitor of p38 MAPK

Chroman 1 

Highly potent and selective ROCK 2 inhibitor; improves cell survival after cryogenesis

A 769662 

Potent AMPK activator

LY 294002 hydrochloride 

Prototypical PI 3-kinase inhibitor; also inhibits other kinases

Emricasan 

Potent pan-caspase inhibitor

PD 98059 

MEK inhibitor

PD 173074 

FGFR1 and -3 inhibitor

RGD peptide 

Minimal recognition sequence for integrin binding; potent integrin inhibitor

Polyamine Supplement x1000 (lyophilized) 

Media supplement to boost cell growth; used as component of CEPT cocktail to enhance stem cell viability

SB 216763 

Potent, selective GSK-3 inhibitor

BIO 

Potent GSK-3 inhibitor; also inhibits cdks

WH-4-023 

Potent and selective Lck and Src inhibitor; also inhibits SIK

Yhhu 3792 

Notch signaling pathway activator; enhances the self-renewal capability of NSCs; active in vivo

A 83-01 

A 83-01 synthesized to Ancillary Material Grade

Troglitazone 

Selective PPARγ agonist; antidiabetic agent

Amiodarone hydrochloride 

Broad spectrum ion channel blocker; antiarrhythmic

Pyrintegrin 

Enhances survival of human ESCs following enzymatic dissociation

INDY 

DYRK1A/B inhibitor

Epiblastin A 

CK1 inhibitor; converts epiblast stem cells to ESCs and promotes ESC self-renewal

Surfen 

Heparin sulfate antagonist

YH 239-EE 

Promotes survival of muscle stem cells (MuSCs); MDM2 inhibitor; activates p53 activity

T3 

T3 synthesized to Ancillary Material Grade

WS 6 

Induces growth and proliferation of pancreatic islet cells, murine totipotent stem cells, GABAergic neurons and hippocampal neurons
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