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Selective ROCK inhibitor; inhibits ROCK1 (p160 ROCK) and ROCK2; stem cell freezing (cryopreservation) media component
Y-27632 synthesized to cGMP guidelines
Potent, selective inhibitor of TGF-βRI, ALK4 and ALK7
SB 431542 synthesized to cGMP guidelines
Selective inhibitor of TGF-βRI, ALK4 and ALK7
Promotes HSCs expansion; increases HSCs engraftment; also endogenous prostaglandin
Selective inhibitor of p38 MAPK
Highly potent and selective ROCK 2 inhibitor; improves cell survival after cryogeneisis
Prototypical PI 3-kinase inhibitor; also inhibits other kinases
Potent, selective GSK-3 inhibitor
Notch signaling pathway activator; enhances the self-renewal capability of NSCs; active in vivo
Selective PPARγ agonist; antidiabetic agent
Potent GSK-3 inhibitor; also inhibits cdks
Enhances survival of human ESCs following enzymatic dissociation
Potent and selective Lck and Src inhibitor; also inhibits SIK
Broad spectrum ion channel blocker; antiarrhythmic
E2F transcription factor inhibitor
CK1 inhibitor; converts epiblast stem cells to ESCs and promotes ESC self-renewal
Heparin sulfate antagonist
Promotes survival of muscle stem cells (MuSCs); MDM2 inhibitor; activates p53 activity
Carrier molecule for stem cell culture; replaces serum albumin for ex vivo stem cell expansion
Potent pan-caspase inhibitor
A 83-01 synthesized to Ancillary Material Grade
T3 synthesized to Ancillary Material Grade