IL-2 R beta Antibody (TM-b1) - BSA Free

Novus Biologicals | Catalog # NBP1-43355

Novus Biologicals
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Key Product Details

Species Reactivity

Mouse

Applications

Block/Neutralize, Flow Cytometry, Immunoprecipitation

Label

Unconjugated

Antibody Source

Monoclonal Rat IgG2B Clone # TM-b1

Format

BSA Free
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Product Specifications

Immunogen

The immunogen for this antibody was Purified CD122.

Clonality

Monoclonal

Host

Rat

Isotype

IgG2B

Scientific Data Images for IL-2 R beta Antibody (TM-b1) - BSA Free

Flow Cytometry: IL-2 R beta Antibody (TM-b1) - BSA Free [NBP1-43355]

Flow Cytometry: IL-2 R beta Antibody (TM-b1) - BSA Free [NBP1-43355]

Flow Cytometry: IL-2 R beta Antibody (TM-b1) [NBP1-43355] - Staining of C57Bl/6 splenocytes with Anti-Mouse NK1.1 APC and 0.25 ug of Rat IgG2b K Isotype Control Purified (left) or 0.5 ug of Anti-Mouse CD122 Purified (right) followed by Anti-Rat IgG Biotin and Streptavidin PE. Cells in the lymphocyte gate were used for analysis.

Applications for IL-2 R beta Antibody (TM-b1) - BSA Free

Application
Recommended Usage

Flow Cytometry

1:10-1:1000

Immunoprecipitation

1:10-1:500
Application Notes
The TM-beta1 antibody has been tested by flow cytometric analysis of mouse splenocyte suspensions. This can be used at less than or equal to 0.5 ug per test. Cell number should be determined empirically but can range from 10^5to 10^8cells/test.

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Formulation, Preparation, and Storage

Purification

Protein A or G purified

Formulation

PBS (pH 7.2)

Format

BSA Free

Preservative

0.09% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C. Do not freeze.

Background: IL-2 R beta

The TM-beta1 monoclonal antibody reacts with mouse CD122, the 90-110 kDa interleukin-2 receptor beta chain (IL-2Rbeta). CD122 is expressed by NK cells and some T cells in the periphery, and is upregulated by activation. CD122 associates with CD25 and CD132 (common gamma chain) to form the high affinity IL-2 receptor. High affinity binding of IL-2 to the IL-2 receptor is inhibited by the TM-beta1 antibody.

Long Name

Interleukin 2 Receptor beta

Alternate Names

CD122, IL-15 R beta, IL-2Rb, IL2R beta, IL2RB

Gene Symbol

IL2RB

Additional IL-2 R beta Products

Product Documents for IL-2 R beta Antibody (TM-b1) - BSA Free

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for IL-2 R beta Antibody (TM-b1) - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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