IL-37/IL-1F7 Antibody - BSA Free

Novus Biologicals | Catalog # NBP2-34208

Novus Biologicals
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Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Immunocytochemistry/ Immunofluorescence

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free
View all IL-37/IL-1F7 Primary Antibodies »

Product Specifications

Immunogen

This antibody was developed against a recombinant protein corresponding to amino acids: ENSGVKMGSEDWEKDEPQCCLEDPAVSPLEPGPSLPAMNFVHTSPKVKNLNPKKFSIHDQDHKVLVLDSGNLIAVPDKNYIRPEIFFALA

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for IL-37/IL-1F7 Antibody - BSA Free

Immunocytochemistry/ Immunofluorescence: IL-37/IL-1F7 Antibody [NBP2-34208]

Immunocytochemistry/ Immunofluorescence: IL-37/IL-1F7 Antibody [NBP2-34208]

Immunocytochemistry/Immunofluorescence: IL-37/IL-1F7 Antibody [NBP2-34208] - Staining of human cell line PC-3 shows localization to nucleoplasm & vesicles. Antibody staining is shown in green.
Immunohistochemistry-Paraffin: IL-37/IL-1F7 Antibody [NBP2-34208]

Immunohistochemistry-Paraffin: IL-37/IL-1F7 Antibody [NBP2-34208]

Immunohistochemistry-Paraffin: IL-37/IL-1F7 Antibody [NBP2-34208] - Staining of human spleen shows positivity in white pulp.

Applications for IL-37/IL-1F7 Antibody - BSA Free

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml

Immunohistochemistry

1:50 - 1:200

Immunohistochemistry-Paraffin

1:50 - 1:200
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. ICC/IF Fixation Permeabilization: Use PFA/Triton X-100.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: IL-37/IL-1F7

IL1F7 is encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine can bind to, and may be a ligand for interleukin 18 receptor (IL18R1/IL-1Rrp). This cytokine also binds to interleukin 18 binding protein (IL18BP), an inhibitory binding protein of interleukin 18 (IL18), and subsequently forms a complex with IL18 receptor beta subunit, and through which it inhibits the activity of IL18. This gene along with eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. Five alternatively spliced transcript variants encoding distinct isoforms have been reported.

Long Name

Interleukin 37

Alternate Names

FIL1 zeta, IL-1F7, IL37

Gene Symbol

IL37

UniProt

Q9NZH6 (Human)

Additional IL-37/IL-1F7 Products

Product Documents for IL-37/IL-1F7 Antibody - BSA Free

Certificate of Analysis

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Product Specific Notices for IL-37/IL-1F7 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Related Research Areas

IL-1 Family

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Protocols

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FAQs

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Associated Pathways

IL-1 Family Signaling Pathways IL-1 Family Signaling Pathway Thumbnail