Human IL-4R alpha ELISA Kit (Colorimetric)

Key Product Details

Product Specifications

Precision

Intra-Assay Precision (Precision within an assay) %CV 5.7 (example only; lot dependent)

Inter-Assay Precision (Precision between assays) %CV 5.6 (example only; lot dependent)

Recovery for Human IL-4R alpha ELISA Kit (Colorimetric)

Kit Contents for Human IL-4R alpha ELISA Kit (Colorimetric)

• Antibody Dilution Buffer
• ELISA Microplate(Dismountable)
• HRP-Streptavidin Conjugate(SABC 100X)
• Instruction Manual
• Lyophilized Standard
• Plate Sealer
• SABC Dilution Buffer
• Sample Dilution Buffer
• Stop Solution
• TMB Substrate
• Wash Buffer (25X)

Preparation and Storage

Background: IL-4R alpha

IL4 is a pleiotropic cytokine produced by activated T cells, mast cells and basophils. It is a ligand for Interleukin 4 receptor. The Interleukin 4 receptor also binds to IL13, which may contribute to many overlapping functions of this cytokine and IL13. IL4 elicits many different biological responses, but has two dominant functions. The first is regulating differentiation of na ve CD4+ T cell to the Th2 type. Th2 cells produce IL4, IL5, IL10 and IL13, which tend to favor a humoral immune response while suppressing a cell mediated immune response controlled by Th1 cells. STAT6, a signal transducer and activator of transcription, has been shown to play a central role in mediating the immune regulatory signal of this cytokine. The second is regulating IgE and IgG1 production by B cells. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.

Additional IL-4R alpha Products

• All Products for IL-4R alpha
• IL-4R alpha cDNA Clones
• IL-4R alpha ELISA Kits
• IL-4R alpha Lysates
• IL-4R alpha Primary Antibodies
• IL-4R alpha Proteins and Enzymes

Product Documents for Human IL-4R alpha ELISA Kit (Colorimetric)