Integrin alpha 1/CD49a Antibody (CL7207) - BSA Free

Novus Biologicals | Catalog # NBP2-76478

Novus Biologicals
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Key Product Details

Validated by

Knockout/Knockdown, Orthogonal Validation

Species Reactivity

Validated:

Human

Cited:

Human

Predicted:

Rat (95%). Backed by our 100% Guarantee.

Applications

Validated:

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Cited:

Block/Neutralize

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 Clone # CL7207

Format

BSA Free
View all Integrin alpha 1/CD49a Primary Antibodies »

Product Specifications

Immunogen

This antibody was developed using a synthetic peptide derived from P56199, with the exact immunogen sequence remaining proprietary.

Reactivity Notes

Mouse (89%).

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Scientific Data Images for Integrin alpha 1/CD49a Antibody (CL7207) - BSA Free

Immunohistochemistry-Paraffin: Integrin alpha 1/CD49a Antibody (CL7207) [NBP2-76478]

Immunohistochemistry-Paraffin: Integrin alpha 1/CD49a Antibody (CL7207) [NBP2-76478]

Immunohistochemistry-Paraffin: Integrin alpha 1/CD49a Antibody (CL7207) [NBP2-76478] - Analysis in human prostate and skeletal muscle tissues. Corresponding ITGA1 RNA-seq data are presented for the same tissues.
Western Blot: Integrin alpha 1/CD49a Antibody (CL7207) [NBP2-76478]

Western Blot: Integrin alpha 1/CD49a Antibody (CL7207) [NBP2-76478]

Western Blot: Integrin alpha 1/CD49a Antibody (CL7207) [NBP2-76478] - Analysis in U-138MG cells transfected with control siRNA, target specific siRNA probe #1 and #2, using Anti-ITGA1 antibody. Remaining relative intensity is presented. Loading control: Anti-GAPDH.
Immunohistochemistry-Paraffin: Integrin alpha 1/CD49a Antibody (CL7207) [NBP2-76478]

Immunohistochemistry-Paraffin: Integrin alpha 1/CD49a Antibody (CL7207) [NBP2-76478]

Immunohistochemistry-Paraffin: Integrin alpha 1/CD49a Antibody (CL7207) [NBP2-76478] - Staining of human placenta shows strong membranous positivity in blood vessels and loose connective tissue of chorionic villi.
Immunohistochemistry-Paraffin: Integrin alpha 1/CD49a Antibody (CL7207) [NBP2-76478]

Immunohistochemistry-Paraffin: Integrin alpha 1/CD49a Antibody (CL7207) [NBP2-76478]

Immunohistochemistry-Paraffin: Integrin alpha 1/CD49a Antibody (CL7207) [NBP2-76478] - Staining of human prostate shows strong membranous positivity in smooth muscle cells.
Immunohistochemistry-Paraffin: Integrin alpha 1/CD49a Antibody (CL7207) [NBP2-76478]

Immunohistochemistry-Paraffin: Integrin alpha 1/CD49a Antibody (CL7207) [NBP2-76478]

Immunohistochemistry-Paraffin: Integrin alpha 1/CD49a Antibody (CL7207) [NBP2-76478] - Staining of human skeletal muscle shows no positivity in striated muscle fibers as expected.
Immunohistochemistry-Paraffin: Integrin alpha 1/CD49a Antibody (CL7207) [NBP2-76478]

Immunohistochemistry-Paraffin: Integrin alpha 1/CD49a Antibody (CL7207) [NBP2-76478]

Immunohistochemistry-Paraffin: Integrin alpha 1/CD49a Antibody (CL7207) [NBP2-76478] - Staining of human stomach shows moderate membranous positivity in glandular cells.

Applications for Integrin alpha 1/CD49a Antibody (CL7207) - BSA Free

Application
Recommended Usage

Immunohistochemistry

1:1000 - 1:2500

Immunohistochemistry-Paraffin

1:1000 - 1:2500

Western Blot

1 ug/ml
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Integrin alpha 1/CD49a

Integrin alpha 1 encodes the alpha 1 subunit of integrin receptors. This protein heterodimerizes with the beta 1 subunit to form a cell-surface receptor for collagen and laminin. The heterodimeric receptor is involved in cell-cell adhesion and may play a role in inflammation and fibrosis. The alpha 1 subunit contains an inserted (I) von Willebrand factor type I domain which is thought to be involved in collagen binding. [provided by RefSeq]

Alternate Names

CD49a, ITGA1, VLA-1

Gene Symbol

ITGA1

Additional Integrin alpha 1/CD49a Products

Product Documents for Integrin alpha 1/CD49a Antibody (CL7207) - BSA Free

Certificate of Analysis

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Product Specific Notices for Integrin alpha 1/CD49a Antibody (CL7207) - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Citations for Integrin alpha 1/CD49a Antibody (CL7207) - BSA Free

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Protocols

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