Integrin alpha 2/CD49b Antibody (CL7318) - Azide and BSA Free

Name: Integrin alpha 2/CD49b Antibody (CL7318) - Azide and BSA Free
Brand: Novus Biologicals
SKU: NBP3-44393
Price: 569 USD
Availability: InStock

Novus Biologicals | Catalog # NBP3-44393

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Product Specifications
Scientific Data
Applications
Preparation & Storage
Calculators
Background
Product Documents
Specific Notices
Research Areas

Key Product Details

Validated by

Orthogonal Validation

Species Reactivity

Human

Applications

Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG₁ Clone # CL7318

Format

Azide and BSA Free

View all Integrin alpha 2/CD49b Primary Antibodies »

Product Specifications

Immunogen

This antibody was generated using a recombinant protein sequence of P17301, with the exact immunogen sequence remaining proprietary.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG₁

Scientific Data Images for Integrin alpha 2/CD49b Antibody (CL7318) - Azide and BSA Free

Immunohistochemistry-Paraffin: Integrin alpha 2/CD49b Antibody [NBP3-44393]

Analysis in human skin and skeletal muscle tissues using NBP3-44393 antibody. Corresponding Integrin alpha 2/CD49b RNA-seq data are presented for the same tissues.

Immunohistochemistry-Paraffin: Integrin alpha 2/CD49b Antibody [NBP3-44393]

Staining of human skeletal muscle shows no positivity in striated muscle fibers as expected.

Immunohistochemistry-Paraffin: Integrin alpha 2/CD49b Antibody [NBP3-44393]

Staining of human prostate shows moderate membranous positivity in glandular cells.

Immunohistochemistry-Paraffin: Integrin alpha 2/CD49b Antibody [NBP3-44393]

Staining of human skin shows strong membranous positivity in cells in basal layer of epidermis.

Western Blot: Integrin alpha 2/CD49b Antibody [NBP3-44393]

Analysis in human cell line RT-4.

Immunohistochemistry-Paraffin: Integrin alpha 2/CD49b Antibody [NBP3-44393]

Staining of human small intestine shows moderate to strong membranous positivity in glandular cells.

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Applications for Integrin alpha 2/CD49b Antibody (CL7318) - Azide and BSA Free

Application

Recommended Usage

Immunohistochemistry-Paraffin

1:200 - 1:500

Western Blot

1 ug/ml

Application Notes

For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Formulation, Preparation, and Storage

Purification

Protein A purified

Reconstitution

Centrifuge the vial of lyophilized antibody at 12,000 x g for 20 seconds. Reconstitute by adding sterile, distilled water to achieve a final antibody concentration of 1mg/ml.

Formulation

Lyophilized from a 0.2 um filtered solution in PBS with Trehalose

Format

Azide and BSA Free

Preservative

No Preservative

Concentration

LYOPH mg/ml

Shipping

The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Calculators

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

Volume (to add to vial)

Mass (in vial)

Desired Reconstitution Concentration

Background: Integrin alpha 2/CD49b

Integrins are heterodimeric cell surface receptors composed of alpha and beta subunits, which mediate cell-cell and cell-extracellular matrix attachments. They are responsible for adhesion of platelets and other cells to collagens, modulation of collagen and collagenase gene expression, force generation and organization of newly synthesized extracellular matrix. Aberrant integrin expression has been found in many epithelial tumours. Changes in integrin expression have been shown to be important for the growth and early metastatic capacity of melanoma cells.

Alternate Names

CD49b, ITGA2, VLA-2 alpha

Gene Symbol

ITGA2

Additional Integrin alpha 2/CD49b Products

Product Documents for Integrin alpha 2/CD49b Antibody (CL7318) - Azide and BSA Free

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Product Specific Notices for Integrin alpha 2/CD49b Antibody (CL7318) - Azide and BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.