kb NB 142-70

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3962/10
3962/50
kb NB 142-70 | CAS No. 1233533-04-4 | Protein Kinase D Inhibitors
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Description: Selective PKD inhibitor; analog of CID 755673 (Cat. No. 3327)

Chemical Name: 9-Hydroxy-3,4-dihydro-2H-[1]-benzothiolo[2,3-f][1,4]thiazepin-5-one

Purity: ≥98%

Product Details
Citations (3)
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Biological Activity

Selective protein kinase D (PKD) inhibitor (IC50 values are 28.3, 58.7 and 53.2 nM for PKD1, 2 and 3 respectively). More potent analog of CID 755673 (Cat. No. 3327) with 7-fold greater inhibition. Inhibits prostrate cancer cell migration and invasion and reduces wound healing in vitro; displays prominent cytotoxic and anti-proliferative effects.

Technical Data

M.Wt:
251.32
Formula:
C11H9NO2S2
Solubility:
Soluble to 100 mM in DMSO
Purity:
≥98%
Storage:
Store at RT
CAS No:
1233533-04-4

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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Citations for kb NB 142-70

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