Chemical Name: 9-Hydroxy-3,4-dihydro-2H--benzothiolo[2,3-f][1,4]thiazepin-5-one
Biological Activity Selective protein kinase D (PKD) inhibitor (IC50 values are 28.3, 58.7 and 53.2 nM for PKD1, 2 and 3 respectively). More potent analog of CID 755673 (Cat. No. 3327) with 7-fold greater inhibition. Inhibits prostrate cancer cell migration and invasion and reduces wound healing in vitro; displays prominent cytotoxic and anti-proliferative effects.
Soluble to 100 mM in DMSO
Store at RT
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