Catalog Number: 0682
Chemical Name: 1-[(4-Hydroxyphenoxy)ethylidene]bis[phosphinylidynebis(oxymethylene)]-2,2-dimethylpropanoate
Biological Activity
Cell-permeable prodrug of the potent inositol monophosphatase inhibitor L-690,330 (Cat. No. 0681); penetrates cells more effectively than its metabolite.
Technical Data
  • M.Wt:
    754.7
  • Formula:
    C32H52O16P2
  • Solubility:
    Soluble to 100 mM in ethanol and to 100 mM in DMSO
  • Purity:
    >98%
  • Storage:
    Store at -80°C
  • CAS No:
    142523-14-6
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Additional Information
Licensing Caveats:
Sold with the permission of Merck Sharp and Dohme Ltd.
Background References
  1. Stimulatory effect of lithium on glucose transport in rat adipocytes is not mediated by elevation of IP1.
    Chen et al.
    Am.J.Physiol., 1998;275:E272
  2. Effects of L-690,488, a prodrug of the bisphosphonate inositol monophosphatase inhibitor L-690,330, on phosphatidylinositol cycle markers.
    Atack et al.
    J.Pharmacol.Exp.Ther., 1994;270:70
Citations:

The citations listed below are publications that use Tocris products. Selected citations for L-690,488 include:

1 Citations: Showing 1 - 1

  1. LtpD is a novel Legionella pneumophila effector that binds phosphatidylinositol 3-phosphate and inositol monophosphatase IMPA1.
    Authors: Harding Et al.
    Mol Cancer 2013;81:4261
Tocris Small Molecules
Description Application Cat# Citations Images  

L-690,330

0681 6  
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