L-CCG-lll

Biological Activity

Technical Data

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Background References

1. 2-Carboxycyclopropyl)glycine: binding, neurotoxicity and induction of intracellular free Ca²⁺ increase.
   Kawai et al.
   Eur.J.Pharmacol., 1992;211:195
2. (2S,3S,4R)-2-(Carboxycyclopropyl)glycine, a potent and competitive inhibitor of both glial and neuronal uptake of glutamate.
   Nakamura et al.
   Neuropharmacology, 1993;32:833
3. Potent NMDA-like actions and potentiation of glutamate responses by conformational variants of a glutamate analogue in the rat spinal cord.
   Shinozaki et al.
   Br.J.Pharmacol., 1989;98:1213
4. Inhibition by folded isomers of L-2-(carboxycyclopropyl)glycine of glutamate uptake via the human glutamate transporter hGluT-I.
   Yamashita et al.
   Eur.J.Pharmacol., 1995;289:387

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