Catalog Number: 0332
Alternate Names: (2S,3S,4R)-CCG
Chemical Name: (2S,1'S,2'R)-2-(Carboxycyclopropyl)glycine
Biological Activity
Potent and competitive inhibitor of both glial and neuronal uptake of glutamate, aspartate and cysteate.
Technical Data
  • M.Wt:
  • Formula:
  • Solubility:
    Soluble to 100 mM in 1eq. NaOH
  • Storage:
    Store at RT
  • CAS No:
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. (2S,3S,4R)-2-(carboxycyclopropyl)glycine, a potent and competitive inhibitor of both glial and neuronal uptake of glutamate.
    Nakamura et al.
    Neuropharmacology, 1993;32:833
  2. 2-Carboxycyclopropyl)glycine: binding, neurotoxicity and induction of intracellular free Ca2+ increase.
    Kawai et al.
    Eur.J.Pharmacol., 1992;211:195
  3. Potent NMDA-like actions and potentiation of glutamate responses by conformational variants of a glutamate analogue in the rat spinal cord.
    Shinozaki et al.
    Br.J.Pharmacol., 1989;98:1213
  4. Inhibition by folded isomers of L-2-(carboxycyclopropyl)glycine of glutamate uptake via the human glutamate transporter hGluT-I.
    Yamashita et al.
    Eur.J.Pharmacol., 1995;289:387
Tocris Bioscience is the leading supplier of novel and exclusive tools for life science research with over 30 years' experience in the industry. Tocris is a Bio-Techne brand.

Order Details


Contact Information

Molarity Calculator
Calculate the mass, volume or concentration required for a solution

The molarity calculator is based on the following equation:

Mass (g) = Concentration (mol/L) x Volume (L) x Molecular Weight (g/mol)
An example of a molarity calculation using the molarity calculator:
What is the mass of compound required to make a 10 mM stock solution in 10 ml of water given that the molecular weight of the compound is 197.13 g/mol?

R&D Systems Guarantee

Certificate of Analysis is currently unavailable on-line. Please contact Customer Service


Customer Information