L-Quisqualic acid

  ( 8 citations )    
Product Datasheet
Catalog Number:0188
Chemical Name:(L)-(+)-α-Amino-3,5-dioxo-1,2,4-oxadiazolidine-2-propanoic acid
Product Details
Citations (8)
Supplemental Products
Reviews
Biological Activity
Glutamate receptor agonist acting at AMPA receptors and metabotropic glutamate receptors positively linked to phosphoinositide hydrolysis. Sensitizes neurons in hippocampus to depolarization by L-AP6 (the so called 'quis' effect). Also available as part of the Group I mGlu Receptor Tocriset™.
Technical Data
  • M.Wt:
    189.13
  • Formula:
    C5H7N3O5
  • Solubility:
    Soluble to 100 mM in 1eq. NaOH and to 10 mM in water
  • Purity:
    >99
  • Storage:
    Store at RT
  • CAS No:
    52809-07-1
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Product Datasheets
COA view current batch
or select another batch:
Citations:

The citations listed below are publications that use Tocris products. Selected citations for L-Quisqualic acid include:

8 Citations: Showing 1 - 8
Filter your results:

  1. HTS-compatible FRET-based conformational sensors clarify membrane receptor activation.
    Authors: Scholler
    Nat Chem Biol  2017;13(4):372
  2. Effects of acute and sustained administration of vortioxetine on the serotonin system in the hippocampus: electrophysiological studies in the rat brain.
    Authors: Mansari Et al.
    Psychopharmacology (Berl)  2015;232:2343
  3. The roads to mitochondrial dysfunction in a rat model of posttraumatic syringomyelia.
    Authors: Hu and Tu
    Biomed Res Int  2015;2015:831490
  4. Restoration of serotonin neuronal firing following long-term administration of bupropion but not paroxetine in olfactory bulbectomized rats.
    Authors: Mansari Et al.
    Int J Neuropsychopharmacol  2015;18
  5. Disruption of GRM1-mediated signalling using riluzole results in DNA damage in melanoma cells.
    Authors: Wall Et al.
    Pigment Cell Melanoma Res  2014;27:263
  6. Fenobam: a clinically validated nonbenzodiazepine anxiolytic is a potent, selective, and noncompetitive mGlu5 receptor antagonist with inverse agonist activity.
    Authors: Porter Et al.
    J Pharmacol Exp Ther  2005;315:711
  7. Interactions between ephrin-B and metabotropic glutamate 1 receptors in brain tissue and cultured neurons.
    Authors: Calò Et al.
    J Neurosci  2005;25:2245
  8. Synergistic interaction between adenosine A2A and glutamate mGlu5 receptors: implications for striatal neuronal function.
    Authors: Ferré Et al.
    Proc Natl Acad Sci U S A  2002;99:11940

FAQs

No product specific FAQs exist for this product, however you may

View all Small Molecule FAQs

Have you used L-Quisqualic acid?

Submit a review and receive a $25US/€18/£15/$25CAN amazon gift card if you include an image - $10US/€7/£6/$10CAN Amazon card for reviews without an image. Limited to verified customers in USA, Canada and Europe.

Tocris Bioscience is the leading supplier of novel and exclusive tools for life science research with over 30 years' experience in the industry. Tocris is a Bio-Techne brand.

Order Details

Contact Us to Order
reload

Feedback

Customer Information
Calculators

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.
=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

R&D Systems Guarantee