L-Quisqualic acid

Key Product Details

Product Description

L-Quisqualic acid is a glutamate receptor agonist acting at AMPA receptors and metabotropic glutamate receptors positively linked to phosphoinositide hydrolysis. L-Quisqualic acid sensitizes neurons in hippocampus to depolarization by L-AP6 (the so called 'quis' effect).

Product Specifications for L-Quisqualic acid

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Preparing Stock Solutions for L-Quisqualic acid

The following data is based on the product molecular weight 189.13.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

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Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	5.29 mL	26.44 mL	52.87 mL
5 mM	1.06 mL	5.29 mL	10.57 mL
10 mM	0.53 mL	2.64 mL	5.29 mL
50 mM	0.11 mL	0.53 mL	1.06 mL

Calculators

Background References

References are publications that support the biological activity of the product. See our Citations tab to view 45 publications citing the usage of this product.

• Porter (S)-Homoquisqualate: a potent agonist at the glutamate metabotropic receptor. Br.J.Pharmacol. 1992 PMID: 1324071
• Schulte Utilization of the resolved L-isomer of 2-amino-6-phosphohexanoic acid (L-AP6) as a selective agonist for a quisqualate-sensitized site in hippocampal CA1 pyramidal neurons. Brain Res. 1994 PMID: 7953634
• Littman Effects of quisqualic acid analogs on metabotropic glutamate receptors coupled to phosphoinositide hydrolysis in rat hippocampus. Neuropharmacology 1995 PMID: 8532164

Product Documents for L-Quisqualic acid