agonist isolated from licorice root (EC50
= 36.5 nM for activation of the ERE tk-Luc reporter by ERβ
in transfected U2OS cells). Displays 20-fold selectivity for ERβ
; does not activate other nuclear receptors, including the androgen and glucocorticoid receptors. Displays anti-inflammatory effects.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Liquiritigenin is a plant-derived highly selective estrogen receptor beta agonist.
Mersereau et al.
Anti-inflammatory effects of liquiritigenin as a consequence of the inhibition of NK-kappaB-dependent iNOS and proinflammatory cytokines production.
Kim et al.
Flavonoid glucosides from licorice.
The citations listed below are publications that use Tocris products. Selected citations for Liquiritigenin include:
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