Chemical Name: (S)-2,3-Dihydro-7-hydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one
Biological ActivityPotent ERβ agonist isolated from licorice root (EC50 = 36.5 nM for activation of the ERE tk-Luc reporter by ERβ in transfected U2OS cells). Displays 20-fold selectivity for ERβ; does not activate other nuclear receptors, including the androgen and glucocorticoid receptors. Displays anti-inflammatory effects.
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Flavonoid glucosides from licorice.
Yahara and Nishioka
Liquiritigenin is a plant-derived highly selective estrogen receptor beta agonist.
Mersereau et al.
Anti-inflammatory effects of liquiritigenin as a consequence of the inhibition of NK-kappaB-dependent iNOS and proinflammatory cytokines production.
Kim et al.
Citation for Liquiritigenin
The citations listed below are publications that use Tocris products. Selected citations for Liquiritigenin include:
1 Citation: Showing 1 - 1
Transcriptomic analysis identifies gene networks regulated by estrogen receptor α (ERα) and ERβ that control distinct effects of different botanical estrogens.
Authors: Gong Et al.
Nucl Recept Signal 2014;12:e001
No product specific FAQs exist for this product, however you mayView all Small Molecule FAQs
Reviews for Liquiritigenin
There are currently no reviews for this product. Be the first to review Liquiritigenin and earn rewards!
Have you used Liquiritigenin?
Submit a review and receive an Amazon gift card.
$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image