Chemical Name: (S)-2,3-Dihydro-7-hydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one
Biological Activity Potent ERβ agonist isolated from licorice root (EC50 = 36.5 nM for activation of the ERE tk-Luc reporter by ERβ in transfected U2OS cells). Displays 20-fold selectivity for ERβ; does not activate other nuclear receptors, including the androgen and glucocorticoid receptors. Displays anti-inflammatory effects.
Soluble to 100 mM in DMSO and to 100 mM in ethanol
Store at -20°C
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