Selective antagonist at progesterone (PR) and glucocorticoid (GR) receptors in vitro
and in vivo
. Is a silent antagonist at PR and has a higher affinity than progesterone. Has higher affinity for GR than dexamethasone
(Cat. No. 1126).
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
RU 38486: a potent antiglucocorticoid in vitro and in vivo.
Gagne et al.
J.Steroid Biochem., 1985;23:247
Molecular mechanism of RU 486 action: a review.
Mao et al.
Binding of the anti-progestin RU 486 to rat ovary steroid receptors.
Schrieber et al.
The citations listed below are publications that use Tocris products. Selected citations for Mifepristone include:
Showing Results 1 - 10 of 17