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MIM1

4762 1 Citation Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
4762/10
4762/50
Cat.No. 4762 - MIM1 | C17H21N3O3S
1 Image
Description: Mcl-1 inhibitor; proapoptotic

Chemical Name: 4-(E)-[[(2Z)-2-cyclohexylimino)-4-methyl-1,3-thiazol-3(2H)-yl]imino]methyl]benzene-1,2,3-triol

Product Details
Citations (1)
Reviews
Biological Activity Technical Data Background Product Datasheets Calculators

Biological Activity

Inhibitor of Mcl-1; selectively targets the BH3-binding pocket. Induces caspase-3/7 activation and cell death in Mcl-1-dependent leukemia cells. Also blocks Mcl-1-mediated suppression of tBID-induced Bax activation in vitro.

Technical Data

M.Wt:
347.43
Formula:
C17H21N3O3S
Solubility:
Soluble to 100 mM in DMSO and to 20 mM in ethanol
Storage:
Store at +4°C

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.

Product Datasheets

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Citation for MIM1

The citations listed below are publications that use Tocris products. Selected citations for MIM1 include:

1 Citation: Showing 1 - 1

  1. The androgen receptor mediates antiapoptotic function in myometrial cells.
    Authors: Li Et al.
    Autophagy  2014;5:e1338

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