(-)-MK 801 maleate

Tocris Bioscience | Catalog # 0955

NMDA antagonist; less active enantiomer of (+)-MK 801
Tocris Bioscience
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Key Product Details

Description

NMDA antagonist; less active enantiomer of (+)-MK 801

Product Description

(-)-MK 801 maleate is a less active enantiomer (10-fold less potent in behavioral studies) than (+)-MK 801 maleate.

(+)-enantiomer also available.

Product Specifications for (-)-MK 801 maleate

Molecular Weight

337.37

Formula

C16H15N.C4H4O4

Storage

Store at RT

Purity

≥98% (HPLC)

Chemical Name

(5R,10S)-(-)-5-Methyl-10,11-dihydro-5H-dibenzo[a,d]cylcohepten-5,10-imine maleate

CAS Number

121917-57-5

PubChem ID

16219612

InChI Key

QLTXKCWMEZIHBJ-FWHYOZOBSA-N

SMILES

O=C(O)/C=C\C(O)=O.C[C@@]14C3=C(C=CC=C3)C[C@H](N4)C2=C1C=CC=C2

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

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Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
water 8.43 25 with gentle warming
DMSO 33.74 100

Preparing Stock Solutions for (-)-MK 801 maleate

The following data is based on the product molecular weight 337.37.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 2.96 mL 14.82 mL 29.64 mL
5 mM 0.59 mL 2.96 mL 5.93 mL
10 mM 0.30 mL 1.48 mL 2.96 mL
50 mM 0.06 mL 0.30 mL 0.59 mL

Calculators

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Background References

References are publications that support the biological activity of the product. See our Citations tab to view 84 publications citing the usage of this product.

Product Documents for (-)-MK 801 maleate

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for (-)-MK 801 maleate

For research use only

Citations for (-)-MK 801 maleate

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