(-)-MK 801 maleate

  ( 3 citations )    
Product Datasheet
Catalog Number:0955
Chemical Name:(5R,10S)-(-)-5-Methyl-10,11-dihydro-5H-dibenzo[a,d]cylcohepten-5,10-imine maleate
Product Details
Citations (3)
Reviews
Biological Activity
Less active enantiomer (10-fold less potent in behavioral studies) than (+)-MK 801 maleate.

(+)-enantiomer also available.

Technical Data
  • M.Wt:
    337.37
  • Formula:
    C16H15N.C4H4O4
  • Solubility:
    Soluble to 25 mM in water with gentle warming and to 100 mM in DMSO
  • Purity:
    >99
  • Storage:
    Store at RT
  • CAS No:
    121917-57-5
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Additional Information
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Citations:

The citations listed below are publications that use Tocris products. Selected citations for (-)-MK 801 maleate include:

3 Citations: Showing 1 - 3
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  1. Actin polymerization and ERK phosphorylation are required for Arc/Arg3.1 mRNA targeting to activated synaptic sites on dendrites.
    Authors: Huang Et al.
    J Neurosci  2007;27:9054
  2. Behavioral stress enhances hippocampal CA1 long-term depression through the blockade of the glutamate uptake.
    Authors: Yang Et al.
    J Pharmacol Exp Ther  2005;25:4288
  3. Astrocyte glutamate transporters regulate metabotropic glutamate receptor-mediated excitation of hippocampal interneurons.
    Authors: Huang Et al.
    J Neurosci  2004;24:4551

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