Mouse Carboxypeptidase A1/CPA1 Antibody
Mouse Carboxypeptidase A1/CPA1 Antibody Summary
Asn17-Tyr419
Accession # Q7TPZ8
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Applications
Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.
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Preparation and Storage
- 12 months from date of receipt, -20 to -70 °C as supplied.
- 1 month, 2 to 8 °C under sterile conditions after reconstitution.
- 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Background: Carboxypeptidase A1/CPA1
Carboxypeptidase A1 encoded by the CPA1 gene cleaves the C-terminal amide or ester bond of peptides that have a free C-terminal carboxyl group (1). It prefers the C-terminal residues with aromatic or branched aliphatic side chains including Phe, Tyr, Trp, Leu or Ile. It is important in the degradation of food proteins to produce essential amino acids such as Phe and Trp. The deduced amino acid sequence of mouse CPA1 consists of a signal peptide (residues 1 to 16), a pro region (residue 17 to 110), and a mature chain (residues 111 to 419). The purified recombinant CPA1 corresponds to the pro form, which can be activated and assayed.
Product Datasheets
Citations for Mouse Carboxypeptidase A1/CPA1 Antibody
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.
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Citations: Showing 1 - 9
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Identification of Novel Ligands for Targeted Antifibrotic Therapy of Chronic Pancreatitis
Authors: J Hung, R Awasthi, AL Klibanov, KA Kelly
International Journal of Nanomedicine, 2021;16(0):5495-5512.
Species: Mouse
Sample Types: Whole Tissue
Applications: IHC -
A gene-environment-induced epigenetic program initiates tumorigenesis
Authors: D Alonso-Cur, YJ Ho, C Burdziak, JLV Maag, JP Morris, R Chandwani, HA Chen, KM Tsanov, FM Barriga, W Luan, N Tasdemir, G Livshits, E Azizi, J Chun, JE Wilkinson, L Mazutis, SD Leach, R Koche, D Pe'er, SW Lowe
Nature, 2021;0(0):.
Species: Mouse
Sample Types: Whole Tissue
Applications: IHC -
Desmoplasia and oncogene driven acinar-to-ductal metaplasia are concurrent events during acinar cell-derived pancreatic cancer initiation in young adult mice
Authors: BL Johnson, M d'Alincour, S Mackenzie-, M D'Apuzzo, HP Shih, ER Manuel, DJ Diamond
PLoS ONE, 2019;14(9):e0221810.
Species: Mouse
Sample Types: Whole Tissue
Applications: IHC-P -
The Loss of ATRX Increases Susceptibility to Pancreatic Injury and Oncogenic KRAS in Female But Not Male Mice
Authors: CC Young, RM Baker, CJ Howlett, T Hryciw, JE Herman, D Higgs, R Gibbons, H Crawford, A Brown, CL Pin
Cell Mol Gastroenterol Hepatol, 2019;7(1):93-113.
Species: Mouse
Sample Types: Tissue Homogenates
Applications: Western Blot -
SEC23B is required for pancreatic acinar cell function in adult mice
Authors: R Khoriaty, N Vogel, MJ Hoenerhoff, MD Sans, G Zhu, L Everett, B Nelson, H Durairaj, B McKnight, B Zhang, SA Ernst, D Ginsburg, JA Williams
Mol. Biol. Cell, 2017;0(0):.
Species: Mouse
Sample Types: Tissue Homogenates
Applications: Western Blot -
Phosphorylation of NEUROG3 Links Endocrine Differentiation to the Cell Cycle in Pancreatic Progenitors
Authors: NAJ Krentz, D van Hoof, Z Li, A Watanabe, M Tang, C Nian, MS German, FC Lynn
Dev. Cell, 2017;41(2):129-142.e6.
Species: Mouse
Sample Types: Whole Tissue
Applications: IHC -
Rab27A Is Present in Mouse Pancreatic Acinar Cells and Is Required for Digestive Enzyme Secretion.
Authors: Hou Y, Ernst S, Stuenkel E, Lentz S, Williams J
PLoS ONE, 2015;10(5):e0125596.
Species: Mouse
Sample Types: Tissue Homogenates
Applications: Western Blot -
A modular and flexible ESC-based mouse model of pancreatic cancer.
Authors: Saborowski, Michael, Saborowski, Anna, Morris, John P 4, Bosbach, Benedikt, Dow, Lukas E, Pelletier, Jerry, Klimstra, David S, Lowe, Scott W
Genes Dev, 2014;28(1):85-97.
Species: Mouse
Sample Types: Whole Tissue
Applications: IHC -
Lineage tracing reveals the dynamic contribution of Hes1+ cells to the developing and adult pancreas.
Authors: Kopinke D, Brailsford M, Shea JE, Leavitt R, Scaife CL, Murtaugh LC
Development, 2011;138(3):431-41.
Species: Mouse
Sample Types: Whole Tissue
Applications: IHC-P
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