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Mouse CXCL2/MIP-2 Quantikine ELISA Kit

Catalog #: MM200
165 Citations Datasheet / COA / SDS
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MM200
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SMM200
Mouse CXCL2/GRO beta/MIP-2/CINC-3 ELISA Standard Curve
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Citations (165)
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Summary Precision Recovery Linearity Data Examples Product Datasheets Preparation and Storage Background Related Research Areas

Mouse CXCL2/MIP-2 Quantikine ELISA Kit Summary

Assay Type
Solid Phase Sandwich ELISA
Format
96-well strip plate
Assay Length
4.5 hours
Sample Type & Volume Required Per Well
Cell Culture Supernates (50 uL), Serum (50 uL)
Sensitivity
1.5 pg/mL
Assay Range
7.8 - 500 pg/mL (Cell Culture Supernates, Serum)
Specificity
Natural and recombinant mouse MIP-2
Cross-reactivity
< 0.5% cross-reactivity observed with available related molecules.Cross-species reactivity not tested.
Interference
No significant interference observed with available related molecules.

Product Summary

The Quantikine Mouse MIP-2 Immunoassay is a 4.5 hour solid phase ELISA designed to measure mouse MIP-2 levels in cell culture supernates and serum. It contains E. coli-expressed recombinant mouse MIP-2 and antibodies raised against the recombinant factor. This immunoassay has been shown to quantitate the recombinant mouse MIP-2 accurately. Results obtained using natural mouse MIP-2 showed dose-response curves that were parallel to the standard curves obtained using the recombinant kit standards. These results indicate that this kit can be used to determine relative mass values for natural mouse MIP-2.

Precision

Intra-Assay Precision (Precision within an assay) Three samples of known concentration were tested on one plate to assess intra-assay precision
Inter-Assay Precision (Precision between assays) Three samples of known concentration were tested in separate assays to assess inter-assay precision

Cell Culture Supernates, Serum

Intra-Assay Precision Inter-Assay Precision
Sample 1 2 3 1 2 3
n 20 20 20 20 20 20
Mean (pg/mL) 17.7 53.9 363 16.9 52.1 346
Standard Deviation 0.5 1.3 7.3 1 2.3 15.4
CV% 2.8 2.4 2 5.9 4.4 4.5

Recovery

The recovery of mouse MIP-2 spiked to three levels throughout the range of the assay in various matrices was evaluated.

Sample Type Average % Recovery Range %
Cell Culture Supernates (n=10) 96 84-110
Serum (n=14) 100 94-116

Linearity

To assess the linearity of the assay, five or more samples containing and/or spiked with various concentrations of mouse MIP-2 in each matrix were diluted with Calibrator Diluent and then assayed.
Mouse CXCL2/GRO beta/MIP-2/CINC-3 ELISA Linearity

Scientific Data

N/A Mouse CXCL2/GRO beta/MIP-2/CINC-3 ELISA Standard Curve View Larger

Mouse CXCL2/GRO beta/MIP-2/CINC-3 ELISA Standard Curve

Product Datasheets

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Preparation and Storage

Storage
Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Background: CXCL2/GRO beta/MIP-2/CINC-3

CXCL2/GRO beta, also called MIP-2 in mouse and CINC-3 in rat, is a member of the CXC chemokine family. Human CXCL2/GRO beta is 107 amino acids (aa) in length with a predicted molecular weight of 11 kDa. The mouse and rat orthologs share 70% and 71% aa sequence identity with the human protein, respectively. N-terminal aa 1-4 of CXCL2/GRO beta can be post-translationally cleaved which confers enhanced hematopoietic bioactivity. CXCL2/GRO beta is produced by a variety of cell types including monocytes and macrophages at sites of inflammation and is chemotactic for granulocytes, including neutrophils.

Entrez Gene IDs:
2920 (Human); 20310 (Mouse); 114105 (Rat)
Alternate Names:
chemokine (C-X-C motif) ligand 2; CINC-2a; CINC3; CINC-3; C-X-C Motif Chemokine 2; CXCL2; GRO beta; GRO2 oncogene; GRO2; GROB; Gro-beta; Growth-regulated protein beta; Macrophage inflammatory protein 2-alpha; melanoma growth stimulatory activity beta; MGSA beta; MGSA-b; MGSA-beta; MIP2; MIP-2; MIP2A; MIP-2a; MIP2-alpha; SCYB2
⚠ WARNING: This product can expose you to chemicals including N,N-Dimethylforamide, which is known to the State of California to cause cancer. For more information, go to www.P65Warnings.ca.gov.

Assay Procedure

Refer to the product for complete assay procedure.

Bring all reagents and samples to room temperature before use. It is recommended that all samples, standards, and controls be assayed in duplicate.
  1.   Prepare all reagents, standard dilutions, and samples as directed in the product insert.
  2.   Remove excess microplate strips from the plate frame, return them to the foil pouch containing the desiccant pack, and reseal.
    3. 50 µL Assay Diluent
  3.   Add 50 µL of Assay Diluent to each well.
    4. 50 µL Standard, Control, or Sample
  4.   Add 50 µL of Standard, Control, or sample to each well. Cover with a plate sealer, and incubate at room temperature for 2 hours.
  5.   Aspirate each well and wash, repeating the process 4 times for a total of 5 washes.
    6. 100 µL Conjugate
  6.   Add 100 µL of Conjugate to each well. Cover with a new plate sealer, and incubate at room temperature for 2 hours.
  7.   Aspirate and wash 5 times.
    8. 100 µL Substrate Solution
  8.   Add 100 µL Substrate Solution to each well. Incubate at room temperature for 30 minutes. PROTECT FROM LIGHT.
    9. 100 µL Stop Solution
  9.   Add 100 µL of Stop Solution to each well. Read at 450 nm within 30 minutes. Set wavelength correction to 540 nm or 570 nm.

Citations for Mouse CXCL2/MIP-2 Quantikine ELISA Kit

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

165 Citations: Showing 1 - 10
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  1. Glutamine prevents acute kidney injury by modulating oxidative stress and apoptosis in tubular epithelial cells
    Authors: K Thomas, L Zondler, N Ludwig, M Kardell, C Lüneburg, K Henke, S Mersmann, A Margraf, T Spieker, T Tekath, A Velic, R Holtmeier, J Hermann, V Jankowski, M Meersch, D Vestweber, M Westphal, J Roth, MA Schäfers, JA Kellum, CA Lowell, J Rossaint, A Zarbock
    JCI Insight, 2022;7(21):.
    Species: Mouse
    Sample Types: Urine
  2. Tubule-mitophagic secretion of SerpinG1 reprograms macrophages to instruct anti-septic acute kidney injury efficacy of high-dose ascorbate mediated by NRF2 transactivation
    Authors: Y Ni, GH Wu, JJ Cai, R Zhang, Y Zheng, JQ Liu, XH Yang, X Yang, Y Shen, JM Lai, XM Ye, SJ Mo
    International journal of biological sciences, 2022;18(13):5168-5184.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  3. Cytokines and Neurodegeneration in Epileptogenesis
    Authors: P Wolinski, D Ksiazek-Wi, A Glabinski
    Brain sciences, 2022;12(3):.
    Species: Mouse
    Sample Types: Tissue Homogenates
  4. Intestinal microbe-dependent ?3 lipid metabolite alphaKetoA prevents inflammatory diseases in mice and cynomolgus macaques
    Authors: T Nagatake, S Kishino, E Urano, H Murakami, N Kitamura, K Konishi, H Ohno, P Tiwari, S Morimoto, E Node, J Adachi, Y Abe, J Isoyama, K Sawane, T Honda, A Inoue, A Uwamizu, T Matsuzaka, Y Miyamoto, SI Hirata, A Saika, Y Shibata, K Hosomi, A Matsunaga, H Shimano, M Arita, J Aoki, M Oka, A Matsutani, T Tomonaga, K Kabashima, M Miyachi, Y Yasutomi, J Ogawa, J Kunisawa
    Mucosal Immunology, 2022;0(0):.
    Species: Mouse
    Sample Types: Tissue Homogenates
  5. SGK1 negatively regulates inflammatory immune responses and protects against alveolar bone loss through modulation of TRAF3 activity
    Authors: X Han, J Ren, H Lohner, L Yakoumatos, R Liang, H Wang
    The Journal of Biological Chemistry, 2022;0(0):102036.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  6. Welding Fume Instillation in Isolated Perfused Mouse Lungs-Effects of Zinc- and Copper-Containing Welding Fumes
    Authors: J Krabbe, T Kraus, H Krabbe, C Martin, P Ziegler
    International Journal of Molecular Sciences, 2022;23(16):.
    Species: Mouse
    Sample Types: Pulmonary Perfusate
  7. Generation of antagonistic monoclonal antibodies against the neoepitope of active mouse interleukin (IL)-18 cleaved by inflammatory caspases
    Authors: Y Uchida, Y Nariai, E Obayashi, Y Tajima, T Koga, A Kawakami, T Urano, H Kamino
    Oncogene, 2022;727(0):109322.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  8. Nanoparticles reduce monocytes within the lungs to improve outcomes after influenza virus infection in aged mice
    Authors: WJ Kelley, KM Wragg, J Chen, T Murthy, Q Xu, MT Boyne Ii, JR Podojil, A Elhofy, DR Goldstein
    JCI Insight, 2022;0(0):.
    Species: Mouse
    Sample Types: BALF
  9. Pseudomonas aeruginosa-induced nociceptor activation increases susceptibility to infection
    Authors: T Lin, D Quellier, J Lamb, T Voisin, P Baral, F Bock, A Schönberg, R Mirchev, G Pier, I Chiu, M Gadjeva
    PloS Pathogens, 2021;17(5):e1009557.
    Species: Mouse
    Sample Types: Tissue Homogenates
  10. Role of S100A8/A9 for Cytokine Secretion, Revealed in Neutrophils Derived from ER-Hoxb8 Progenitors
    Authors: Y Zhou, J Hann, V Schenten, S Plançon, JL Bueb, F Tolle, S Bréchard
    International Journal of Molecular Sciences, 2021;22(16):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  11. Cysteine-Capped Hydrogels Incorporating Copper as Effective Antimicrobial Materials against Methicillin-Resistant Staphylococcus aureus
    Authors: JJ Yang, YC Huang, TH Chuang, DR Herr, MF Hsieh, CJ Huang, CM Huang
    Microorganisms, 2020;8(2):.
    Species: Mouse
    Sample Types: Tissue Homogenates
  12. Nintedanib Reduces Neutrophil Chemotaxis via Activating GRK2 in Bleomycin-Induced Pulmonary Fibrosis
    Authors: WC Chen, NJ Chen, HP Chen, WK Yu, VY Su, H Chen, HH Wu, KY Yang
    Int J Mol Sci, 2020;21(13):.
    Species: Mouse
    Sample Types: Tissue Homogenates
  13. ASK1 promotes uterine inflammation leading to pathological preterm birth
    Authors: M Yoshikawa, T Iriyama, K Suzuki, S Sayama, T Tsuruga, K Kumasawa, T Nagamatsu, K Homma, I Naguro, Y Osuga, H Ichijo, T Fujii
    Sci Rep, 2020;10(1):1887.
    Species: Mouse
    Sample Types: Peritoneal Fluid
  14. The Gustatory Sensory G-Protein GNAT3 Suppresses Pancreatic Cancer Progression in Mice
    Authors: MT Hoffman, SB Kemp, DJ Salas-Esca, Y Zhang, NG Steele, S The, D Long, S Benitz, W Yan, RF Margolskee, F Bednar, M Pasca di M, HJ Wen, HC Crawford
    Cell Mol Gastroenterol Hepatol, 2020;0(0):.
    Species: Mouse
    Sample Types: Tissue Homogenates
  15. Phorbol 12-Myristate 13-Acetate Induced Toxicity Study and the Role of Tangeretin in Abrogating HIF-1&alpha-NF-&kappaB Crosstalk In Vitro and In Vivo
    Authors: SN Chang, DK Dey, ST Oh, WH Kong, KH Cho, EM Al-Olayan, BS Hwang, SC Kang, JG Park
    International Journal of Molecular Sciences, 2020;21(23):.
    Species: Mouse
    Sample Types: Tissue Culture Supernates
  16. Induced Pluripotent Stem Cells Regulate TREM-1 Expression and the p38 MAPK Pathway in Endotoxin-Induced Acute Lung Injury
    Authors: VY Su, KY Yang, SH Chiou, NJ Chen, MH Mo, CS Lin, CT Wang
    Stem Cells, 2019;0(0):.
    Species: Mouse
    Sample Types: Tissue Homogenates
  17. Adoptive transfer of type 1 regulatory T cells suppressed the development of airway hyperresponsiveness in ovalbumin-induced airway inflammation model mice
    Authors: M Matsuda, K Doi, T Tsutsumi, M Inaba, J Hamaguchi, T Terada, R Kawata, K Kitatani, T Nabe
    J. Pharmacol. Sci., 2019;141(4):139-145.
    Species: Mouse
    Sample Types: BALF
  18. Ovalbumin-sensitized mice have altered airway inflammation to agriculture organic dust
    Authors: KJ Warren, JD Dickinson, AJ Nelson, TA Wyatt, DJ Romberger, JA Poole
    Respir. Res., 2019;20(1):51.
    Species: Mouse
    Sample Types: BALF
  19. Tofacitinib enhances delivery of antibody-based therapeutics to tumor cells through modulation of inflammatory cells
    Authors: N Simon, A Antignani, SM Hewitt, M Gadina, C Alewine, D FitzGerald
    JCI Insight, 2019;0(0):.
    Species: Mouse
    Sample Types: Serum
  20. Lack of whey acidic protein four disulphide core (WFDC) 2 protease inhibitor causes neonatal death from respiratory failure in mice
    Authors: K Nakajima, M Ono, U Radovi?, S Dizdarevi?, SI Tomizawa, K Kuroha, G Naganatsu, I Hoshi, R Matsunaga, T Shirakawa, T Kurosawa, Y Miyazaki, M Seki, Y Suzuki, H Koseki, M Nakamura, T Suda, K Ohbo
    Dis Model Mech, 2019;0(0):.
    Species: Mouse
    Sample Types: Tissue Homogenates
  21. 1-Palmitoyl-2-linoleoyl-3-acetyl-rac-glycerol (PLAG) attenuates gemcitabine-induced neutrophil extravasation
    Authors: J Jeong, YJ Kim, DY Lee, BG Moon, KY Sohn, SY Yoon, JW Kim
    Cell Biosci, 2019;9(0):4.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  22. Isoflavone Aglycones Attenuate Cigarette Smoke-Induced Emphysema via Suppression of Neutrophilic Inflammation in a COPD Murine Model
    Authors: K Kojima, K Asai, H Kubo, A Sugitani, Y Kyomoto, A Okamoto, K Yamada, N Ijiri, T Watanabe, K Hirata, T Kawaguchi
    Nutrients, 2019;11(9):.
    Species: Mouse
    Sample Types: BALF
  23. Inactivation of MTOR promotes autophagy-mediated epithelial injury in particulate matter-induced airway inflammation
    Authors: YF Wu, ZY Li, LL Dong, WJ Li, YP Wu, J Wang, HP Chen, HW Liu, M Li, CL Jin, HQ Huang, SM Ying, W Li, HH Shen, ZH Chen
    Autophagy, 2019;0(0):1-16.
    Species: Mouse
    Sample Types: BALF
  24. MTOR Suppresses Environmental Particle-Induced Inflammatory Response in Macrophages
    Authors: Z Li, Y Wu, H Chen, C Zhu, L Dong, Y Wang, H Liu, X Xu, J Zhou, Y Wu, W Li, S Ying, H Shen, Z Chen
    J. Immunol., 2018;0(0):.
    Species: Mouse
    Sample Types: BALF
  25. Snail promotes ovarian cancer progression by recruiting myeloid-derived suppressor cells via CXCR2 ligand upregulation
    Authors: M Taki, K Abiko, T Baba, J Hamanishi, K Yamaguchi, R Murakami, K Yamanoi, N Horikawa, Y Hosoe, E Nakamura, A Sugiyama, M Mandai, I Konishi, N Matsumura
    Nat Commun, 2018;9(1):1685.
    Species: Mouse
    Sample Types: Serum
  26. TIM?4 blockade of KCs combined with exogenous TGF?β injection helps to reverse acute rejection and prolong the survival rate of mice receiving liver allografts
    Authors: H Wu, X Xu, J Li, J Gong, M Li
    Int. J. Mol. Med., 2018;0(0):.
    Species: Mouse
    Sample Types: Tissue Homogenates
  27. Endothelial cell-specific anticoagulation reduces inflammation in a mouse model of acute lung injury
    Authors: J Lou, Y Hu, MD Wu, LQ Che, YF Wu, Y Zhao, BP Tian, ZQ Bao, C Zhu, YP Wu, LL He, CX Bai, J Zhou, SM Ying, W Li, ZH Chen, DX Chen, A Dorling, HH Shen
    Acta Pharmacol. Sin., 2018;0(0):.
  28. Two novel roles of buffalo milk lactoperoxidase, antibiofilm agent and immunomodulator against multidrug resistant Salmonella enterica serovar Typhi and Listeria monocytogenes
    Authors: L Mahdi, H Musafer, L Zwain, I Salman, I Al-Joofy, K Rasool, A Mussa, S Al-Kakei, R Al-Oqaili, S Al-Alak, A Chaloob, A Abdulkaree, B Hussein, N Mahdi, N Taher
    Microb. Pathog., 2017;0(0):.
    Species: Mouse
    Sample Types: Serum
  29. Age-related decline of the acute local inflammation response: a mitigating role for the adenosine A2A receptor
    Authors: C Laflamme, GB Mailhot, M Pouliot
    Aging (Albany NY), 2017;9(10):2083-2097.
    Species: Mouse
    Sample Types: Air Pouch Exudate
  30. Antiinflammatory actions of inorganic nitrate stabilize the atherosclerotic plaque
    Authors: RS Khambata, SM Ghosh, KS Rathod, T Thevathasa, F Filomena, Q Xiao, A Ahluwalia
    Proc. Natl. Acad. Sci. U.S.A, 2017;0(0):.
    Species: Mouse
    Sample Types: Plasma
  31. Toll-Like Receptor 4 Signaling Pathway Mediates Inhalant Organic Dust-Induced Bone Loss
    PLoS ONE, 2016;11(8):e0158735.
  32. CF Lung Infection and Inflammation: IL-17 Pathophysiology and Therapeutic Intervention
    Authors: Daniel Hsu
    Infect Immun, 2016;0(0):.
    Species: Mouse
    Sample Types: BALF
  33. Targeting thrombomodulin to circulating red blood cells augments its protective effects in models of endotoxemia and ischemia-reperfusion injury
    Authors: Vladimir R Muzykantov
    FASEB J., 2016;0(0):.
    Species: Mouse
    Sample Types: Plasma
  34. Toll-like Receptor 4 Agonistic Antibody Promotes Host Defense against Chronic Pseudomonas aeruginosa Lung Infection in Mice
    Authors: S Nakamura, N Iwanaga, M Seki, K Fukudome, K Oshima, T Miyazaki, K Izumikawa, K Yanagihara, Y Miyazaki, H Mukae, S Kohno
    Infect Immun, 2016;0(0):.
    Species: Mouse
    Sample Types: Tissue Homogenates
  35. CD11c.DTR mice develop a fatal fulminant myocarditis after local or systemic treatment with diphtheria toxin
    Eur J Immunol, 2016;0(0):.
    Species: Mouse
    Sample Types: Tissue Homogenates
  36. Plasminogen activator inhibitor-1 does not contribute to the pulmonary pathology induced by acute exposure to ozone
    Physiol Rep, 2016;4(18):.
    Species: Mouse
    Sample Types: BALF
  37. Systemic IL-6 Effector Response in Mediating Systemic Bone Loss Following Inhalation of Organic Dust
    Authors: Jill A Poole
    J. Interferon Cytokine Res., 2016;0(0):.
    Species: Mouse
    Sample Types: BALF
  38. DUOX-Mediated Signaling Is Not Required for LPS-Induced Neutrophilic Response in the Airways.
    Authors: Chang S, Linderholm A, Harper R
    PLoS ONE, 2015;10(7):e0131810.
    Species: Mouse
    Sample Types: BALF
  39. Blau syndrome-associated Nod2 mutation alters expression of full-length NOD2 and limits responses to muramyl dipeptide in knock-in mice.
    Authors: Dugan J, Griffiths E, Snow P, Rosenzweig H, Lee E, Brown B, Carr D, Rose C, Rosenbaum J, Davey M
    J Immunol, 2015;194(1):349-57.
    Species: Mouse
    Sample Types: Serum
  40. Conditioned media from adipose stromal cells limit lipopolysaccharide-induced lung injury, endothelial hyperpermeability and apoptosis.
    Authors: Lu H, Poirier C, Cook T, Traktuev D, Merfeld-Clauss S, Lease B, Petrache I, March K, Bogatcheva N
    J Transl Med, 2015;13(0):67.
    Species: Mouse
    Sample Types: BALF
  41. Peripheral blood monocyte-derived chemokine blockade prevents murine transfusion-related acute lung injury (TRALI).
    Authors: McKenzie C, Kim M, Singh T, Milev Y, Freedman J, Semple J
    Blood, 2014;123(22):3496-503.
    Species: Mouse
    Sample Types: Serum
  42. Fibrates ameliorate the course of bacterial sepsis by promoting neutrophil recruitment via CXCR2.
    Authors: Tancevski I, Nairz M, Duwensee K, Auer K, Schroll A, Heim C, Feistritzer C, Hoefer J, Gerner R, Moschen A, Heller I, Pallweber P, Li X, Theurl M, Demetz E, Wolf A, Wolf D, Eller P, Ritsch A, Weiss G
    EMBO Mol Med, 2014;6(6):810-20.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  43. CXCR2-mediated tumor-associated neutrophil recruitment is regulated by IFN-beta.
    Authors: Jablonska J, Wu C, Andzinski L, Leschner S, Weiss S
    Int J Cancer, 2014;134(6):1346-58.
    Species: Mouse
    Sample Types: Tissue Homogenates
  44. Nuclear factor of activated T cells regulates neutrophil recruitment, systemic inflammation, and T-cell dysfunction in abdominal sepsis.
    Authors: Zhang S, Luo L, Wang Y, Gomez M, Thorlacius H
    Infect Immun, 2014;82(8):3275-88.
    Species: Mouse
    Sample Types: Tissue Homogenates
  45. Recombinant human hyaluronidase PH20 does not stimulate an acute inflammatory response and inhibits lipopolysaccharide-induced neutrophil recruitment in the air pouch model of inflammation.
    Authors: Huang Z, Zhao C, Chen Y, Cowell J, Wei G, Kultti A, Huang L, Thompson C, Rosengren S, Frost G, Shepard H
    J Immunol, 2014;192(11):5285-95.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  46. Characterization of a distinct host response profile to Pneumocystis murina asci during clearance of pneumocystis pneumonia.
    Authors: Linke M, Ashbaugh A, Collins M, Lynch K, Cushion M
    Infect Immun, 2013;81(3):984-95.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  47. Vascular immunotargeting to endothelial determinant ICAM-1 enables optimal partnering of recombinant scFv-thrombomodulin fusion with endogenous cofactor.
    Authors: Greineder, Colin F, Chacko, Ann-Mari, Zaytsev, Sergei, Zern, Blaine J, Carnemolla, Ronald, Hood, Elizabet, Han, Jingyan, Ding, Bi-Sen, Esmon, Charles, Muzykantov, Vladimir
    PLoS ONE, 2013;8(11):e80110.
    Species: Mouse
    Sample Types: Lavage Fluid
  48. Inhibition of geranylgeranyltransferase attenuates neutrophil accumulation and tissue injury in severe acute pancreatitis.
    Authors: Merza M, Wetterholm E, Zhang S, Regner S, Thorlacius H
    J Leukoc Biol, 2013;94(3):493-502.
    Species: Mouse
    Sample Types: Tissue Homogenates
  49. A novel C5a-neutralizing mirror-image (l-)aptamer prevents organ failure and improves survival in experimental sepsis.
    Authors: Hoehlig, Kai, Maasch, Christia, Shushakova, Nelli, Buchner, Klaus, Huber-Lang, Markus, Purschke, Werner G, Vater, Axel, Klussmann, Sven
    Mol Ther, 2013;21(12):2236-46.
    Species: Mouse
    Sample Types: Peritoneal Lavage Fluid
  50. Modelling of mouse experimental colitis by global property screens: a holistic approach to assess drug effects in inflammatory bowel disease.
    Authors: Gottfries J, Melgar S, Michaelsson E
    PLoS ONE, 2012;7(1):e30005.
    Species: Mouse
    Sample Types: Tissue Homogenates
  51. CRTH2 Is A Critical Regulator of Neutrophil Migration and Resistance to Polymicrobial Sepsis.
    Authors: Ishii M, Asano K, Namkoong H, Tasaka S, Mizoguchi K, Asami T, Kamata H, Kimizuka Y, Fujiwara H, Funatsu Y, Kagawa S, Miyata J, Ishii K, Nakamura M, Hirai H, Nagata K, Kunkel SL, Hasegawa N, Betsuyaku T
    J. Immunol., 2012;188(11):5655-64.
    Species: Mouse
    Sample Types: Peritoneal Lavage Fluid
  52. Human mesenchymal stem/stromal cells cultured as spheroids are self-activated to produce prostaglandin E2 that directs stimulated macrophages into an anti-inflammatory phenotype.
    Authors: Ylostalo J, Bartosh T, Coble K, Prockop D
    Stem Cells, 2012;30(10):2283-96.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  53. Priming with endotoxin increases acute lung injury in mice by enhancing the severity of lung endothelial injury.
    Authors: Lee JS, Su X, Rackley C, Matthay MA, Gupta N
    Anat Rec (Hoboken), 2012;294(1):165-72.
    Species: Mouse
    Sample Types: BALF
  54. Inhibiting Mer receptor tyrosine kinase suppresses STAT1, SOCS1/3, and NF-kappaB activation and enhances inflammatory responses in lipopolysaccharide-induced acute lung injury.
    J. Cell. Sci., 2012;91(6):921-32.
    Species: Mouse
    Sample Types: BALF
  55. Neutrophil-derived matrix metalloproteinase-9 is a potent activator of trypsinogen in acinar cells in acute pancreatitis.
    Authors: Awla D, Abdulla A, Syk I, Jeppsson B, Regner S, Thorlacius H
    J. Leukoc. Biol., 2012;91(5):711-9.
    Species: Mouse
    Sample Types: Serum
  56. Endothelial cell peroxisome proliferator-activated receptor gamma reduces endotoxemic pulmonary inflammation and injury.
    Authors: Reddy A, Lakshmi S, Kleinhenz J, Sutliff R, Hart C, Reddy R
    J Immunol, 2012;189(11):5411-20.
    Species: Mouse
    Sample Types: BALF
  57. TLR4 through IFN-beta promotes low molecular mass hyaluronan-induced neutrophil apoptosis.
    Authors: Leu SW, Shi L, Xu C, Zhao Y, Liu B, Li Y, Shiedlin A, Xiang C, Shen H, Quinn DA, Hales CA, Zhao H
    J. Immunol., 2011;186(1):556-62.
    Species: Mouse
    Sample Types: BALF
  58. TNF-alpha promotes LPA1- and LPA3-mediated recruitment of leukocytes in vivo through CXCR2 ligand chemokines.
    Authors: Zhao C, Sardella A, Chun J, Poubelle PE, Fernandes MJ, Bourgoin SG
    J. Lipid Res., 2011;52(7):1307-18.
    Species: Mouse
    Sample Types: Air Pouch Exudate
  59. CXCL1 and its receptor, CXCR2, mediate murine sickle cell vaso-occlusion during hemolytic transfusion reactions.
    Authors: Jang JE, Hod EA, Spitalnik SL
    J. Clin. Invest., 2011;121(4):1397-401.
    Species: Mouse
    Sample Types: Plasma
  60. Suppression of cytokine storm with a sphingosine analog provides protection against pathogenic influenza virus.
    Authors: Walsh KB, Teijaro JR, Wilker PR
    Proc. Natl. Acad. Sci. U.S.A., 2011;108(29):12018-23.
    Species: Mouse
    Sample Types: BALF
  61. Involvement of adenosine A2A receptors in engulfment-dependent apoptotic cell suppression of inflammation.
    Authors: Koroskenyi K, Duro E, Pallai A, Sarang Z, Kloor D, Ucker DS, Beceiro S, Castrillo A, Chawla A, Ledent CA, Fésüs L, Szondy Z
    J. Immunol., 2011;186(12):7144-55.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  62. Overexpression of sICAM-1 in the Alveolar Epithelial Space Results in an Exaggerated Inflammatory Response and Early Death in Gram Negative Pneumonia.
    Authors: Mendez MP, Monroy YK, Du M
    Respir. Res., 2011;12(1):12.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  63. Enhanced production of IL-17A during zymosan-induced peritonitis in obese mice.
    Authors: Pini M, Fantuzzi G
    J. Leukoc. Biol., 2010;87(1):51-8.
    Species: Mouse
    Sample Types: Peritoneal Lavage Fluid
  64. P2X7 receptor activation induces CXCL2 production in microglia through NFAT and PKC/MAPK pathways.
    Authors: Shiratori M, Tozaki-Saitoh H, Yoshitake M
    J. Neurochem., 2010;114(3):810-9.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  65. NOD1 contributes to mouse host defense against Helicobacter pylori via induction of type I IFN and activation of the ISGF3 signaling pathway.
    Authors: Watanabe T, Asano N, Fichtner-Feigl S, Gorelick PL, Tsuji Y, Matsumoto Y, Chiba T, Fuss IJ, Kitani A, Strober W
    J. Clin. Invest., 2010;120(5):1645-62.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  66. S100A8/A9 is not involved in host defense against murine urinary tract infection.
    Authors: Dessing MC, Butter LM, Teske GJ
    PLoS ONE, 2010;5(10):e13394.
    Species: Mouse
    Sample Types: Tissue Homogenates
  67. TLR4 is a negative regulator in noninfectious lung inflammation.
    Authors: Zhao H, Leu SW, Shi L, Dedaj R, Zhao G, Garg HG, Shen L, Lien E, Fitzgerald KA, Shiedlin A, Shen H, Quinn DA, Hales CA
    J. Immunol., 2010;184(9):5308-14.
    Species: Mouse
    Sample Types: BALF
  68. Epithelial overexpression of SOCS-3 in transgenic mice exacerbates wound inflammation in the presence of elevated TGF-beta1.
    Authors: Linke A, Goren I, Bosl MR, Pfeilschifter J, Frank S
    J. Invest. Dermatol., 2010;130(3):866-75.
    Species: Mouse
    Sample Types: Tissue Homogenates
  69. Recipient T lymphocytes modulate the severity of antibody-mediated transfusion-related acute lung injury.
    Authors: Fung YL, Kim M, Tabuchi A
    Blood, 2010;116(16):3073-9.
    Species: Mouse
    Sample Types: Serum
  70. Absence or inhibition of matrix metalloproteinase-8 decreases ventilator-induced lung injury.
    Authors: Albaiceta GM, Gutierrez-Fernandez A, Garcia-Prieto E, Puente XS, Parra D, Astudillo A, Campestre C, Cabrera S, Gonzalez-Lopez A, Fueyo A, Taboada F, Lopez-Otin C
    Am. J. Respir. Cell Mol. Biol., 2010;43(5):555-63.
    Species: Mouse
    Sample Types: Tissue Homogenates
  71. Ability of IDO to attenuate liver injury in alpha-galactosylceramide-induced hepatitis model.
    Authors: Ito H, Hoshi M, Ohtaki H, Taguchi A, Ando K, Ishikawa T, Osawa Y, Hara A, Moriwaki H, Saito K, Seishima M
    J. Immunol., 2010;185(8):4554-60.
    Species: Mouse
    Sample Types: Serum
  72. Early protection from burn-induced acute lung injury by deletion of preprotachykinin-A gene.
    Authors: Sio SW, Moochhala S, Lu J
    Am. J. Respir. Crit. Care Med., 2010;181(1):36-46.
    Species: Mouse
    Sample Types: Tissue Homogenates
  73. Varying susceptibility of pulmonary cytokine production to lipopolysaccharide in mice.
    Authors: Alm AS, Li K, Yang D, Andersson R, Lu Y, Wang X
    Cytokine, 2010;49(3):256-63.
    Species: Mouse
    Sample Types: BALF
  74. Uropathogenic Escherichia coli modulates immune responses and its curli fimbriae interact with the antimicrobial peptide LL-37.
    Authors: Kai-Larsen Y, Luthje P, Chromek M, Peters V, Wang X, Holm A, Kadas L, Hedlund KO, Johansson J, Chapman MR, Jacobson SH, Romling U, Agerberth B, Brauner A
    PLoS Pathog., 2010;6(0):e1001010.
    Species: Mouse
    Sample Types: Urine
  75. Anchoring fusion thrombomodulin to the endothelial lumen protects against injury-induced lung thrombosis and inflammation.
    Authors: Ding BS, Hong N, Christofidou-Solomidou M, Gottstein C, Albelda SM, Cines DB, Fisher AB, Muzykantov VR
    Am. J. Respir. Crit. Care Med., 2009;180(3):247-56.
    Species: Mouse
    Sample Types: BALF
  76. T cells dampen innate immune responses through inhibition of NLRP1 and NLRP3 inflammasomes.
    Authors: Guarda G, Dostert C, Staehli F, Cabalzar K, Castillo R, Tardivel A, Schneider P, Tschopp J
    Nature, 2009;460(7252):269-73.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  77. Both FcgammaRIV and FcgammaRIII are essential receptors mediating type II and type III autoimmune responses via FcRgamma-LAT-dependent generation of C5a.
    Authors: Syed SN, Konrad S, Wiege K, Nieswandt B, Nimmerjahn F, Schmidt RE, Gessner JE
    Eur. J. Immunol., 2009;39(12):3343-56.
    Species: Mouse
    Sample Types: BALF
  78. Plasminogen activator inhibitor-1 regulates neutrophil influx during acute pyelonephritis.
    Authors: Roelofs JJ, Teske GJ, Bonta PI, de Vries CJ, Meijers JC, Weening JJ, van der Poll T, Florquin S
    Kidney Int., 2009;75(1):52-9.
    Species: Mouse
    Sample Types: Tissue Homogenates
  79. The E-selectin ligand basigin/CD147 is responsible for neutrophil recruitment in renal ischemia/reperfusion.
    Authors: Kato N, Yuzawa Y, Kosugi T
    J. Am. Soc. Nephrol., 2009;20(7):1565-76.
    Species: Mouse
    Sample Types: Tissue Homogenates
  80. A small molecule CRTH2 antagonist inhibits FITC-induced allergic cutaneous inflammation.
    Authors: Boehme SA, Franz-Bacon K, Chen EP, Sasik R, Sprague LJ, Ly TW, Hardiman G, Bacon KB
    Int. Immunol., 2009;21(1):81-93.
    Species: Mouse
    Sample Types: Tissue Homogenates
  81. C/EBPalpha is required for pulmonary cytoprotection during hyperoxia.
    Authors: Xu Y, Saegusa C, Schehr A, Grant S, Whitsett JA, Ikegami M
    Am. J. Physiol. Lung Cell Mol. Physiol., 2009;297(2):L286-98.
    Species: Mouse
    Sample Types: Tissue Homogenates
  82. Bbeta(15-42) protects against acid-induced acute lung injury and secondary pseudomonas pneumonia in vivo.
    Authors: Matt U, Warszawska JM, Bauer M, Dietl W, Mesteri I, Doninger B, Haslinger I, Schabbauer G, Perkmann T, Binder CJ, Reingruber S, Petzelbauer P, Knapp S
    Am. J. Respir. Crit. Care Med., 2009;180(12):1208-17.
    Species: Mouse
    Sample Types: BALF
  83. IL-17 receptor signaling is required to control polymicrobial sepsis.
    Authors: Freitas A, Alves-Filho JC, Victoni T, Secher T, Lemos HP, Sonego F, Cunha FQ, Ryffel B
    J. Immunol., 2009;182(12):7846-54.
    Species: Mouse
    Sample Types: Tissue Secretion
  84. Acute lung injury is reduced in fat-1 mice endogenously synthesizing n-3 fatty acids.
    Authors: Mayer K, Kiessling A, Ott J, Schaefer MB, Hecker M, Henneke I, Schulz R, Gunther A, Wang J, Wu L, Roth J, Seeger W, Kang JX
    Am. J. Respir. Crit. Care Med., 2009;179(6):474-83.
    Species: Mouse
    Sample Types: BALF
  85. TLR9 activation coupled to IL-10 deficiency induces adverse pregnancy outcomes.
    Authors: Thaxton JE, Romero R, Sharma S
    J. Immunol., 2009;183(2):1144-54.
    Species: Mouse
    Sample Types: Serum
  86. Syndecan-1 shedding facilitates the resolution of neutrophilic inflammation by removing sequestered CXC chemokines.
    Authors: Hayashida K, Parks WC, Park PW
    Blood, 2009;114(14):3033-43.
    Species: Mouse
    Sample Types: Serum
  87. Neutrophil chemokines KC and macrophage-inflammatory protein-2 are newly synthesized by tissue macrophages using distinct TLR signaling pathways.
    Authors: De Filippo K, Henderson RB, Laschinger M, Hogg N
    J. Immunol., 2008;180(6):4308-15.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  88. The neuropeptide substance P is a critical mediator of burn-induced acute lung injury.
    Authors: Sio SW, Puthia MK, Lu J, Moochhala S, Bhatia M
    J. Immunol., 2008;180(12):8333-41.
    Species: Mouse
    Sample Types: Tissue Homogenates
  89. Role and regulation of adipokines during zymosan-induced peritoneal inflammation in mice.
    Authors: Pini M, Gove ME, Sennello JA, van Baal JW, Chan L, Fantuzzi G
    Endocrinology, 2008;149(8):4080-5.
    Species: Mouse
    Sample Types: Serum
  90. Matrix metalloproteinase-7 (matrilysin) controls neutrophil egress by generating chemokine gradients.
    Authors: Swee M, Wilson CL, Wang Y, McGuire JK, Parks WC
    J. Leukoc. Biol., 2008;83(6):1404-12.
    Species: Mouse
    Sample Types: Lavage Fluid
  91. Matrix metalloproteinase-8 facilitates neutrophil migration through the corneal stromal matrix by collagen degradation and production of the chemotactic peptide Pro-Gly-Pro.
    Authors: Lin M, Jackson P, Tester AM, Diaconu E, Overall CM, Blalock JE, Pearlman E
    Am. J. Pathol., 2008;173(1):144-53.
    Species: Mouse
    Sample Types: Tissue Homogenates
  92. Effects of epithelial and neutrophil CXCR2 on innate immunity and resistance to kidney infection.
    Authors: Svensson M, Irjala H, Svanborg C, Godaly G
    Kidney Int., 2008;74(1):81-90.
    Species: Mouse
    Sample Types: Urine
  93. The nuclear factor kappa-B pathway in airway epithelium regulates neutrophil recruitment and host defence following Pseudomonas aeruginosa infection.
    Authors: Chen SM, Cheng DS, Williams BJ, Sherrill TP, Han W, Chont M, Saint-Jean L, Christman JW, Sadikot RT, Yull FE, Blackwell TS
    Clin. Exp. Immunol., 2008;0(0):.
    Species: Mouse
    Sample Types: BALF
  94. A novel mechanism for CCR4 in the regulation of macrophage activation in bleomycin-induced pulmonary fibrosis.
    Authors: Trujillo G, O'Connor EC, Kunkel SL, Hogaboam CM
    Am. J. Pathol., 2008;172(5):1209-21.
    Species: Mouse
    Sample Types: Tissue Homogenates
  95. Endogenous hydrogen sulfide regulates inflammatory response by activating the ERK pathway in polymicrobial sepsis.
    Authors: Zhang H, Moochhala SM, Bhatia M
    J. Immunol., 2008;181(6):4320-31.
    Species: Mouse
    Sample Types: Tissue Homogenates
  96. Neutrophil-toxin interactions promote antigen delivery and mucosal clearance of Streptococcus pneumoniae.
    Authors: Matthias KA, Roche AM, Standish AJ, Shchepetov M, Weiser JN
    J. Immunol., 2008;180(9):6246-54.
    Species: Mouse
    Sample Types: Nasal Lavage Fluid
  97. Functional roles for C5a receptors in sepsis.
    Authors: Rittirsch D, Flierl MA, Nadeau BA, Day DE, Huber-Lang M, Mackay CR, Zetoune FS, Gerard NP, Cianflone K, Kohl J, Gerard C, Sarma JV, Ward PA
    Nat. Med., 2008;14(5):551-7.
    Species: Mouse
    Sample Types: Plasma
  98. Myeloid Src kinases regulate phagocytosis and oxidative burst in pneumococcal meningitis by activating NADPH oxidase.
    Authors: Paul R, Obermaier B, Van Ziffle J, Angele B, Pfister HW, Lowell CA, Koedel U
    J. Leukoc. Biol., 2008;84(4):1141-50.
    Species: Mouse
    Sample Types: Tissue Homogenates
  99. Adverse functions of IL-17A in experimental sepsis.
    Authors: Flierl MA, Rittirsch D, Gao H, Hoesel LM, Nadeau BA, Day DE, Zetoune FS, Sarma JV, Huber-Lang MS, Ferrara JL, Ward PA
    FASEB J., 2008;22(7):2198-205.
    Species: Mouse
    Sample Types: Plasma
  100. CD47 deficiency protects mice from lipopolysaccharide-induced acute lung injury and Escherichia coli pneumonia.
    Authors: Su X, Johansen M, Looney MR, Brown EJ, Matthay MA
    J. Immunol., 2008;180(10):6947-53.
    Species: Mouse
    Sample Types: BALF
  101. Particulate matter in cigarette smoke alters iron homeostasis to produce a biological effect.
    Authors: Ghio AJ, Hilborn ED, Stonehuerner JG, Dailey LA, Carter JD, Richards JH, Crissman KM, Foronjy RF, Uyeminami DL, Pinkerton KE
    Am. J. Respir. Crit. Care Med., 2008;178(11):1130-8.
    Species: Rat
    Sample Types: BALF
  102. Mouse models of rhinovirus-induced disease and exacerbation of allergic airway inflammation.
    Authors: Bartlett NW, Walton RP, Edwards MR, Aniscenko J, Caramori G, Zhu J, Glanville N, Choy KJ, Jourdan P, Burnet J, Tuthill TJ, Pedrick MS, Hurle MJ, Plumpton C, Sharp NA, Bussell JN, Swallow DM, Schwarze J, Guy B, Almond JW, Jeffery PK, Lloyd CM, Papi A, Killington RA, Rowlands DJ, Blair ED, Clarke NJ, Johnston SL
    Nat. Med., 2008;14(2):199-204.
    Species: Mouse
    Sample Types: BALF
  103. Cytokine production by M-CSF- and GM-CSF-induced mouse bone marrow-derived macrophages upon coculturing with late apoptotic cells.
    Authors: Yamazaki T, Nagata K, Kobayashi Y
    Cell. Immunol., 2008;251(2):124-30.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  104. Functional Th1 cells are required for surgical adhesion formation in a murine model.
    Authors: Tzianabos AO, Holsti MA, Zheng XX, Stucchi AF, Kuchroo VK, Strom TB, Glimcher LH, Cruikshank WW
    J. Immunol., 2008;180(10):6970-6.
  105. Peroxisome proliferator-activated receptor-gamma ligand, 15-deoxy-Delta12,14-prostaglandin J2, reduces neutrophil migration via a nitric oxide pathway.
    Authors: Napimoga MH, Vieira SM, Dal-Secco D, Freitas A, Souto FO, Mestriner FL, Alves-Filho JC, Grespan R, Kawai T, Ferreira SH, Cunha FQ
    J. Immunol., 2008;180(1):609-17.
    Species: Mouse
    Sample Types: Tissue Secretion
  106. TLR-2 and IL-17A in chitin-induced macrophage activation and acute inflammation.
    Authors: Da Silva CA, Hartl D, Liu W, Lee CG, Elias JA
    J. Immunol., 2008;181(6):4279-86.
    Species: Mouse
    Sample Types: BALF
  107. P-selectin glycoprotein ligand-1 regulates chemokine-dependent leukocyte recruitment in colonic ischemia-reperfusion.
    Authors: Santen S, Schramm R, Menger MD, Wang Y, Jeppsson B, Thorlacius H
    Inflamm. Res., 2007;56(11):452-8.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  108. CD44 regulates macrophage recruitment to the lung in lipopolysaccharide-induced airway disease.
    Authors: Hollingsworth JW, Li Z, Brass DM, Garantziotis S, Timberlake SH, Kim A, Hossain I, Savani RC, Schwartz DA
    Am. J. Respir. Cell Mol. Biol., 2007;37(2):248-53.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  109. ST2 is essential for Th2 responsiveness and resistance to pseudomonas aeruginosa keratitis.
    Authors: Huang X, Du W, Barrett RP, Hazlett LD
    Invest. Ophthalmol. Vis. Sci., 2007;48(10):4626-33.
    Species: Mouse
    Sample Types: Tissue Homogenates
  110. Differential roles of p55 and p75 tumor necrosis factor receptors on stretch-induced pulmonary edema in mice.
    Authors: Wilson MR, Goddard ME, O&amp;amp;apos;Dea KP, O'Dea KP, Choudhury S, Takata M
    Am. J. Physiol. Lung Cell Mol. Physiol., 2007;293(1):L60-8.
    Species: Mouse
    Sample Types: BALF
  111. Toll-like receptor 4 (TLR4)-dependent proinflammatory and immunomodulatory properties of the glycoinositolphospholipid (GIPL) from Trypanosoma cruzi.
    Authors: Medeiros MM, Peixoto JR, Oliveira AC, Cardilo-Reis L, Koatz VL, Van Kaer L, Previato JO, Mendonca-Previato L, Nobrega A, Bellio M
    J. Leukoc. Biol., 2007;82(3):488-96.
    Species: Mouse
    Sample Types: Peritoneal Fluid
  112. Keratinocyte growth factor protects against elastase-induced pulmonary emphysema in mice.
    Authors: Plantier L, Marchand-Adam S, Antico VG, Boyer L, De Coster C, Marchal J, Bachoual R, Mailleux A, Boczkowski J, Crestani B
    Am. J. Physiol. Lung Cell Mol. Physiol., 2007;293(5):L1230-9.
    Species: Mouse
    Sample Types: BALF
  113. Cathepsin-G interferes with clearance of Pseudomonas aeruginosa from mouse lungs.
    Authors: Sedor J, Hogue L, Akers K, Boslaugh S, Schreiber J, Ferkol T
    Pediatr. Res., 2007;61(1):26-31.
    Species: Mouse
    Sample Types: BALF
  114. TLR2 is constitutively expressed within the kidney and participates in ischemic renal injury through both MyD88-dependent and -independent pathways.
    Authors: Shigeoka AA, Holscher TD, King AJ, Hall FW, Kiosses WB, Tobias PS, Mackman N, McKay DB
    J. Immunol., 2007;178(10):6252-8.
    Species: Mouse
    Sample Types: Tissue Homogenates
  115. Regulation of systemic and local neutrophil responses by G-CSF during pulmonary Pseudomonas aeruginosa infection.
    Authors: Gregory AD, Hogue LA, Ferkol TW, Link DC
    Blood, 2007;109(8):3235-43.
    Species: Mouse
    Sample Types: Epithelial Fluid
  116. Soluble vascular endothelial growth factor receptor-1 protects mice in sepsis.
    Authors: Tsao PN, Chan FT, Wei SC, Hsieh WS, Chou HC, Su YN, Chen CY, Hsu WM, Hsieh FJ, Hsu SM
    Crit. Care Med., 2007;35(8):1955-60.
    Species: Mouse
    Sample Types: Plasma
  117. Cannabinoid-2 receptor agonist HU-308 protects against hepatic ischemia/reperfusion injury by attenuating oxidative stress, inflammatory response, and apoptosis.
    Authors: Rajesh M, Pan H, Mukhopadhyay P, Batkai S, Osei-Hyiaman D, Hasko G, Liaudet L, Gao B, Pacher P
    J. Leukoc. Biol., 2007;82(6):1382-9.
    Species: Mouse
    Sample Types: Plasma
  118. C3a is required for the production of CXC chemokines by tubular epithelial cells after renal ishemia/reperfusion.
    Authors: Thurman JM, Lenderink AM, Royer PA, Coleman KE, Zhou J, Lambris JD, Nemenoff RA, Quigg RJ, Holers VM
    J. Immunol., 2007;178(3):1819-28.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  119. Src homology 2 domain-containing inositol 5-phosphatase 1 deficiency leads to a spontaneous allergic inflammation in the murine lung.
    Authors: Oh SY, Zheng T, Bailey ML, Barber DL, Schroeder JT, Kim YK, Zhu Z
    J. Allergy Clin. Immunol., 2007;119(1):123-31.
    Species: Mouse
    Sample Types: BALF
  120. Mice lacking NKCC1 are protected from development of bacteremia and hypothermic sepsis secondary to bacterial pneumonia.
    Authors: Nguyen M, Pace AJ, Koller BH
    J. Exp. Med., 2007;204(6):1383-93.
    Species: Mouse
    Sample Types: Tissue Homogenates
  121. IL-17 receptor signaling influences virus-induced corneal inflammation.
    Authors: Molesworth-Kenyon SJ, Yin R, Oakes JE, Lausch RN
    J. Leukoc. Biol., 2007;83(2):401-8.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  122. The Duffy antigen receptor for chemokines in acute renal failure: A facilitator of renal chemokine presentation.
    Authors: Zarbock A, Schmolke M, Bockhorn SG, Scharte M, Buschmann K, Ley K, Singbartl K
    Crit. Care Med., 2007;35(9):2156-63.
    Species: Mouse
    Sample Types: Tissue Homogenates
  123. Cathelicidin-deficient (Cnlp -/- ) mice show increased susceptibility to Pseudomonas aeruginosa keratitis.
    Authors: Huang LC, Reins RY, Gallo RL, McDermott AM
    Invest. Ophthalmol. Vis. Sci., 2007;48(10):4498-508.
    Species: Mouse
    Sample Types: Tissue Homogenates
  124. Increased inflammation delays wound healing in mice deficient in collagenase-2 (MMP-8).
    Authors: Gutierrez-Fernandez A, Inada M, Balbin M, Fueyo A, Pitiot AS, Astudillo A, Hirose K, Hirata M, Shapiro SD, Noel A, Werb Z, Krane SM, Lopez-Otin C, Puente XS
    FASEB J., 2007;21(10):2580-91.
    Species: Mouse
    Sample Types: Tissue Homogenates
  125. Clostridium sordellii lethal toxin kills mice by inducing a major increase in lung vascular permeability.
    Authors: Geny B, Khun H, Fitting C, Zarantonelli L, Mazuet C, Cayet N, Szatanik M, Prevost MC, Cavaillon JM, Huerre M, Popoff MR
    Am. J. Pathol., 2007;170(3):1003-17.
    Species: Mouse
    Sample Types: Serum
  126. Delayed inflammatory response to primary pneumonic plague occurs in both outbred and inbred mice.
    Authors: Bubeck SS, Cantwell AM, Dube PH
    Infect. Immun., 2007;75(2):697-705.
    Species: Mouse
    Sample Types: BALF
  127. Interleukin-1beta is the primary initiator of pulmonary inflammation following liver injury in mice.
    Authors: Glasgow SC, Ramachandran S, Blackwell TS, Mohanakumar T, Chapman WC
    Am. J. Physiol. Lung Cell Mol. Physiol., 2007;293(2):L491-6.
    Species: Mouse
    Sample Types: Serum
  128. Inflammasome-mediated production of IL-1beta is required for neutrophil recruitment against Staphylococcus aureus in vivo.
    Authors: Miller LS, Pietras EM, Uricchio LH, Hirano K, Rao S, Lin H, O'Connell RM, Iwakura Y, Cheung AL, Cheng G, Modlin RL
    J. Immunol., 2007;179(10):6933-42.
    Species: Mouse
    Sample Types: Tissue Homogenates
  129. Intrapulmonary delivery of bone marrow-derived mesenchymal stem cells improves survival and attenuates endotoxin-induced acute lung injury in mice.
    Authors: Gupta N, Su X, Popov B, Lee JW, Serikov V, Matthay MA
    J. Immunol., 2007;179(3):1855-63.
    Species: Mouse
    Sample Types: BALF
  130. Local production of chemokines and prostaglandin E2 in the acute, chronic and recovery phase of murine experimental colitis.
    Authors: Drmotova M, Rehnstrom E, Jansson L
    Cytokine, 2006;35(5):275-83.
    Species: Mouse
    Sample Types: Tissue Homogenates
  131. GM-CSF and the impaired pulmonary innate immune response following hyperoxic stress.
    Authors: Baleeiro CE, Christensen PJ, Morris SB, Mendez MP, Wilcoxen SE, Paine R
    Am. J. Physiol. Lung Cell Mol. Physiol., 2006;291(6):L1246-55.
    Species: Mouse
    Sample Types: Tissue Homogenates
  132. The urokinase plasminogen activator receptor is crucially involved in host defense during acute pyelonephritis.
    Authors: Roelofs JJ, Rouschop KM, Teske GJ, Claessen N, Weening JJ, van der Poll T, Florquin S
    Kidney Int., 2006;70(11):1942-7.
    Species: Mouse
    Sample Types: Tissue Homogenates
  133. Bone marrow-derived cells require a functional glucose 6-phosphate transporter for normal myeloid functions.
    Authors: Kim SY, Nguyen AD, Gao JL, Murphy PM, Mansfield BC, Chou JY
    J. Biol. Chem., 2006;281(39):28794-801.
    Species: Mouse
    Sample Types: Plasma
  134. The macrophage scavenger receptor SR-AI/II and lung defense against pneumococci and particles.
    Authors: Arredouani MS, Yang Z, Imrich A, Ning Y, Qin G, Kobzik L
    Am. J. Respir. Cell Mol. Biol., 2006;35(4):474-8.
    Species: Mouse
    Sample Types: BALF
  135. High expression of ligands for chemokine receptor CXCR2 in alveolar epithelial neoplasia induced by oncogenic kras.
    Authors: Wislez M, Fujimoto N, Izzo JG, Hanna AE, Cody DD, Langley RR, Tang H, Burdick MD, Sato M, Minna JD, Mao L, Wistuba I, Strieter RM, Kurie JM
    Cancer Res., 2006;66(8):4198-207.
    Species: Mouse
    Sample Types: Tissue Homogenates
  136. Delayed inflammatory responses to endotoxin in fibrinogen-deficient mice.
    Authors: Cruz-Topete D, Iwaki T, Ploplis VA, Castellino FJ
    J. Pathol., 2006;210(3):325-33.
    Species: Mouse
    Sample Types: Plasma
  137. The transcriptional response to lipopolysaccharide reveals a role for interferon-gamma in lung neutrophil recruitment.
    Authors: Burch LH, Yang IV, Whitehead GS, Chao FG, Berman KG, Schwartz DA
    Am. J. Physiol. Lung Cell Mol. Physiol., 2006;291(4):L677-82.
    Species: Mouse
    Sample Types: BALF
  138. A coagulation factor VII deficiency protects against acute inflammatory responses in mice.
    Authors: Xu H, Ploplis VA, Castellino FJ
    J. Pathol., 2006;210(4):488-96.
    Species: Mouse
    Sample Types: Plasma
  139. Adenosine A2A receptor inactivation increases survival in polymicrobial sepsis.
    Authors: Nemeth ZH, Csoka B, Wilmanski J, Xu D, Lu Q, Ledent C, Deitch EA, Pacher P, Spolarics Z, Hasko G
    J. Immunol., 2006;176(9):5616-26.
    Species: Mouse
    Sample Types: Plasma
  140. CD27 contributes to the early systemic immune response to Mycobacterium tuberculosis infection but does not affect outcome.
    Authors: Wieland CW, Kerver ME, Florquin S, Nolte MA, Borst J, van Lier R, van Oers MH, van der Poll T
    Int. Immunol., 2006;18(11):1531-9.
    Species: Mouse
    Sample Types: Tissue Homogenates
  141. Human CXCR2 (hCXCR2) takes over functionalities of its murine homolog in hCXCR2 knockin mice.
    Authors: Mihara K, Smit MJ, Krajnc-Franken M, Gossen J, Rooseboom M, Dokter W
    Eur. J. Immunol., 2005;35(9):2573-82.
    Species: Mouse
    Sample Types: Serum
  142. Endogenous interleukin-12 improves the early antimicrobial host response to murine Escherichia coli peritonitis.
    Authors: Weijer S, Florquin S, van der Poll T
    Shock, 2005;23(1):54-8.
    Species: Mouse
    Sample Types: Peritoneal Fluid
  143. Interleukin-17 as a recruitment and survival factor for airway macrophages in allergic airway inflammation.
    Authors: Sergejeva S, Ivanov S, Lotvall J, Linden A
    Am. J. Respir. Cell Mol. Biol., 2005;33(3):248-53.
    Species: Mouse
    Sample Types: BALF
  144. The class A macrophage scavenger receptor attenuates CXC chemokine production and the early infiltration of neutrophils in sterile peritonitis.
    Authors: Cotena A, Platt N
    J. Immunol., 2004;173(10):6427-32.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  145. Regulation of Pseudomonas aeruginosa corneal infection in IL-1 beta converting enzyme (ICE, caspase-1) deficient mice.
    Authors: Thakur A, Barrett RP, McClellan S, Hazlett LD
    Curr. Eye Res., 2004;29(4):225-33.
    Species: Mouse
    Sample Types: Tissue Homogenates
  146. T cell-specific ablation of Fas leads to Fas ligand-mediated lymphocyte depletion and inflammatory pulmonary fibrosis.
    Authors: Hao Z, Hampel B, Yagita H, Rajewsky K
    J. Exp. Med., 2004;199(10):1355-65.
    Species: Mouse
    Sample Types: Serum
  147. Circulating CXC-chemokine concentrations in a murine intestinal ischemia-reperfusion model.
    Authors: Maheshwari A, Christensen RD, Calhoun DA
    Fetal Pediatr Pathol, 2004;23(2):145-57.
    Species: Mouse
    Sample Types: Serum
  148. IL-22 increases the innate immunity of tissues.
    Authors: Wolk K, Kunz S, Witte E, Friedrich M, Asadullah K, Sabat R
    Immunity, 2004;21(2):241-54.
    Species: Mouse
    Sample Types: Plasma
  149. Transcription regulation of TNF-alpha-early response genes by poly(ADP-ribose) polymerase-1 in murine heart endothelial cells.
    Authors: Carrillo A, Monreal Y, Ramirez P, Marin L, Parrilla P, Oliver FJ, Yelamos J
    Nucleic Acids Res., 2004;32(2):757-66.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  150. Chemokine and cytokine production during Orientia tsutsugamushi infection in mice.
    Authors: Koh YS, Yun JH, Seong SY, Choi MS, Kim IS
    Microb. Pathog., 2004;36(1):51-7.
    Species: Mouse
    Sample Types: Peritoneal Fluid
  151. IL-17, produced by lymphocytes and neutrophils, is necessary for lipopolysaccharide-induced airway neutrophilia: IL-15 as a possible trigger.
    Authors: Ferretti S, Bonneau O, Dubois GR, Jones CE, Trifilieff A
    J. Immunol., 2003;170(4):2106-12.
    Species: Mouse
    Sample Types: BALF
  152. CD40 plays a crucial role in lipopolysaccharide-induced acute lung injury.
    Authors: Hashimoto N, Kawabe T, Imaizumi K, Hara T, Okamoto M, Kojima K, Shimokata K, Hasegawa Y
    Am. J. Respir. Cell Mol. Biol., 2003;30(6):808-15.
    Species: Mouse
    Sample Types: BALF
  153. Thrombomodulin mutant mice with a strongly reduced capacity to generate activated protein C have an unaltered pulmonary immune response to respiratory pathogens and lipopolysaccharide.
    Authors: Rijneveld AW, Weijer S, Florquin S, Esmon CT, Meijers JC, Speelman P, Reitsma PH, ten Cate H, van der Poll T
    Blood, 2003;103(5):1702-9.
    Species: Mouse
    Sample Types: BALF
  154. Selective I kappa B kinase expression in airway epithelium generates neutrophilic lung inflammation.
    Authors: Sadikot RT, Han W, Everhart MB, Zoia O, Peebles RS, Jansen ED, Yull FE, Christman JW, Blackwell TS
    J. Immunol., 2003;170(2):1091-8.
    Species: Mouse
    Sample Types: BALF
  155. Interleukin-10 negatively regulates local cytokine and chemokine production but does not influence antibacterial host defense during murine pneumococcal meningitis.
    Authors: Zwijnenburg PJ, van der Poll T, Florquin S, Roord JJ, van Furth AM
    Infect. Immun., 2003;71(4):2276-9.
    Species: Mouse
    Sample Types: Tissue Homogenates
  156. Endogenous IL-17 as a mediator of neutrophil recruitment caused by endotoxin exposure in mouse airways.
    Authors: Miyamoto M, Prause O, Sjostrand M, Laan M, Lotvall J, Linden A
    J. Immunol., 2003;170(9):4665-72.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  157. Cutting edge: myeloid differentiation factor 88 deficiency improves resistance against sepsis caused by polymicrobial infection.
    Authors: Weighardt H, Bê Ë&#x1D;„Æ%í&#x05;, Kaiser-Moore S, Vabulas RM, Kirschning CJ, Wagner H, Holzmann B
    , 2002;169(6):2823-7.
    Species: Mouse
    Sample Types: Serum
  158. Neutrophil-mediated mycobacteriocidal immunity in the lung during Mycobacterium bovis BCG infection in C57BL/6 mice.
    Authors: Fulton SA, Reba SM, Martin TD, Boom WH
    Infect. Immun., 2002;70(9):5322-7.
    Species: Mouse
    Sample Types: BALF
  159. Overexpression of extracellular superoxide dismutase decreases lung injury after exposure to oil fly ash.
    Authors: Ghio AJ, 107303, Suliman HB, Carter JD, Abushamaa AM, Folz RJ
    Am. J. Physiol. Lung Cell Mol. Physiol., 2002;283(1):L211-8.
    Species: Mouse
    Sample Types: Tracheal Lavage Fluid
  160. Resident cell chemokine expression serves as the major mechanism for leukocyte recruitment during local inflammation.
    Authors: Garcia-Ramallo E, Marques T, Prats N, Beleta J, Kunkel SL, Godessart N
    J. Immunol., 2002;169(11):6467-73.
    Species: Mouse
    Sample Types: Air Pouch Exudate
  161. Rapid up-regulation of CXC chemokines in the airways after Ag-specific CD4+ T cell activation.
    Authors: Knott PG, Gater PR, Dunford PJ, Fuentes ME, Bertrand CP
    J. Immunol., 2001;166(2):1233-40.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  162. Requirement of interleukin 17 receptor signaling for lung CXC chemokine and granulocyte colony-stimulating factor expression, neutrophil recruitment, and host defense.
    Authors: Ye P, Rodriguez FH, Kanaly S, Stocking KL, Schurr J, Schwarzenberger P, Oliver P, Huang W, Zhang P, Zhang J, Shellito JE, Bagby GJ, Nelson S, Charrier K, Peschon JJ, Kolls JK
    J. Exp. Med., 2001;194(4):519-27.
    Species: Mouse
    Sample Types: BALF
  163. The protein tyrosine kinase inhibitor AG126 prevents the massive microglial cytokine induction by pneumococcal cell walls.
    Authors: Hanisch UK, Prinz M, Angstwurm K, Hausler KG, Kann O, Kettenmann H, Weber JR
    Eur. J. Immunol., 2001;31(7):2104-15.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  164. Il-6 and its soluble receptor orchestrate a temporal switch in the pattern of leukocyte recruitment seen during acute inflammation.
    Authors: Hurst SM, Wilkinson TS, McLoughlin RM, Jones S, Horiuchi S, Yamamoto N, Rose-John S, Fuller GM, Topley N, Jones SA
    Immunity, 2001;14(6):705-14.
    Species: Mouse
    Sample Types: Peritoneal Lavage Fluid
  165. Inhibition of lipopolysaccharide-induced signal transduction in endotoxin-tolerized mouse macrophages: dysregulation of cytokine, chemokine, and toll-like receptor 2 and 4 gene expression.
    Authors: Medvedev AE, Kopydlowski KM, Vogel SN
    J. Immunol., 2000;164(11):5564-74.
    Species: Mouse
    Sample Types: Cell Culture Supernates

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