Mouse Epigen Biotinylated Antibody

U.S. Patent No. 6,150,502
Catalog # Availability Size / Price Qty
Product Details
Supplemental Products

Mouse Epigen Biotinylated Antibody Summary

Species Reactivity
Detects mouse Epigen in ELISAs and Western blots. In sandwich immunoassays, less than 0.1% cross-reactivity with recombinant mouse (rm) Amphiregulin, rmBTC, rmEpiregulin and recombinant human HB-EGF is observed.
Polyclonal Goat IgG
Antigen Affinity-purified
E. coli-derived recombinant mouse Epigen (R&D Systems, Catalog # 1127-EP)
Accession # Q924X1
Lyophilized from a 0.2 μm filtered solution in PBS with BSA as a carrier protein.


Recommended Concentration
Western Blot
0.1 µg/mL
Recombinant Mouse Epigen (Catalog # 1127-EP)

Mouse Epigen Sandwich Immunoassay

Recommended Concentration
ELISA Detection (Matched Antibody Pair)
0.1-0.4 µg/mL 

Use in combination with:

Capture Reagent: Mouse Epigen Antibody (Catalog # MAB11271)

Standard: Recombinant Mouse Epigen Protein (Catalog # 1127-EP)

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Reconstitution Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.


Preparation and Storage

Reconstitute at 0.2 mg/mL in sterile PBS.
Reconstitution Buffer Available
Reconstitution Buffer 1 (PBS)
Catalog #
Size / Price
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: Epigen

Epigen is an eipthelial mitogen that belongs to the EGF superfamily (1). Mouse Epigen cDNA encodes a 153 amino acid (aa) residue type I transmembrane precursor protein with a 18 aa putative signal peptide, a 92 aa extracellular domain, a 20 aa transmembrane domain and a 22 aa cytoplasmic domain. Expression of mouse Epigen has been detected in multiple tissues including testis, liver and heart. Over the entire protein, mouse Epigen shares from approximately 23% to 33% sequence homology with other EGF family members. The functional internal peptide containing the EGF motif however is more than 40% homologous with that of TGF-alpha and epiregulin. A human cDNA clone encoding a mouse epigen-like protein has also been identified (2). Similarly to other EGF family proteins, a soluble form of mouse Epigen can most likely be generated from the membrane-bound form by proteolytic cleavage. Although recombinant mouse Epigen has been shown to be mitogenic for fibroblasts (3) and epithelial cells (1), compared to EGF and TGF-alpha, it is much less potent. The EGF receptor ErbB1 can be activated upon mouse Epigen activation. Nevertheless, involvements of additional ErbB receptors in mouse Epigen signaling have not been ruled out.

  1. Strachan, L. et al. (2001) J. Biol. Chem. 276:18265.
  2. Accession XM_171078.
  3. R&D Systems, unpublished results.
Entrez Gene IDs
255324 (Human); 71920 (Mouse)
Alternate Names
ALGV3072; EPG; EPGN; Epigen; PRO9904

Product Datasheets

You must select a language.


Product Specific Notices

U.S. Patent No. 6,150,502 used under license from Genesis Research and Development Corporation Limited.


No product specific FAQs exist for this product, however you may

View all Antibody FAQs

Reviews for Mouse Epigen Biotinylated Antibody

There are currently no reviews for this product. Be the first to review Mouse Epigen Biotinylated Antibody and earn rewards!

Have you used Mouse Epigen Biotinylated Antibody?

Submit a review and receive an Amazon gift card.

$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review