Key Product Details

Species Reactivity

Validated:

Mouse

Cited:

Mouse

Applications

Validated:

Western Blot

Cited:

ELISA Development

Label

Biotin

Antibody Source

Polyclonal Goat IgG
View all IGFALS/ALS Primary Antibodies »

Product Specifications

Immunogen

Mouse myeloma cell line NS0-derived recombinant mouse IGFALS/ALS
Thr28-Cys603
Accession # P70389

Specificity

Detects mouse  IGFALS/ALS in Western blots.

Clonality

Polyclonal

Host

Goat

Isotype

IgG

Applications for Mouse IGFALS/ALS Biotinylated Antibody

Application
Recommended Usage

Western Blot

0.1 µg/mL
Sample: Recombinant Mouse IGFALS/ALS

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Reconstitution

Reconstitute at 0.2 mg/mL in sterile PBS.

Formulation

Lyophilized from a 0.2 μm filtered solution in PBS with BSA as a carrier protein.

Shipping

The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.

Calculators

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

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Background: IGFALS/ALS

ALS (Acid labile subunit) is an 84-86 kDa glycoprotein member of the leucine rich repeat superfamily of molecules. It is secreted by hepatocytes in response to growth hormone stimulation, and forms a 140-150 kDa ternary complex with IGFBP3 (or IGFBP5) and IGF-I. This complex increases the half-life of IGF-I and retains it in the circulation for use in multiple tissues. Mature mouse ALS is 580 amino acids (aa) in length (aa 24-603). It contains twenty-one 20-23 aa LRRs that participate in protein-protein interactions. There are two potential isoform variants that show N-terminal extensions. One contains a 66 aa substitution for aa 1-5, while another possesses an 89 aa substitution again for aa 1-5. Over aa 28-603, mouse ALS shares 79% and 93% aa identity with human and rat ALS, respectively.        

Long Name

IGF-binding Protein Acid Labile Subunit

Alternate Names

ACLSD, ALS

Entrez Gene IDs

3483 (Human); 16005 (Mouse)

Gene Symbol

IGFALS

UniProt

P70389

Additional IGFALS/ALS Products

Product Documents for Mouse IGFALS/ALS Biotinylated Antibody

Certificate of Analysis

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Note: Certificate of Analysis not available for kit components.

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Product Specific Notices for Mouse IGFALS/ALS Biotinylated Antibody

For research use only

Citations for Mouse IGFALS/ALS Biotinylated Antibody

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