Interleukin 1 receptor accessory protein-like 2 (IL1RAPL2), also known as TIGIRR-1 and IL-1 R9, is a member of the IL-1 RI-like family of the IL-1 R/Toll-like receptor superfamily. IL1RAPL2 is a type I transmembrane protein that contains three Ig-like domains in its extracellular region and one intracellular TIR domain. IL1RAPL2 is expressed in the central nervous system, and its deletion is associated with some forms of X-linked mental retardation. An alternately spliced variant lacks the transmembrane and cytoplasmic regions. Within their extracellular domains, mouse IL1RAPL2 shares 99% amino acid sequence identity with human IL1RAPL2.
Key Product Details
Species Reactivity
Mouse
Applications
Western Blot
Label
Unconjugated
Antibody Source
Monoclonal Rat IgG2A Clone # 320017
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Product Specifications
Immunogen
Mouse myeloma cell line NS0-derived recombinant mouse IL1RAPL2
Asn18-Ala358
Accession # Q9ERS6
Asn18-Ala358
Accession # Q9ERS6
Specificity
Detects mouse IL1RAPL2 in direct ELISAs and Western blots. In direct ELISAs and Western blots, approximately 25% cross‑reactivity with recombinant human (rh) IL1RAPL2 is observed and no cross-reactivity with recombinant mouse (rm) IL-1 R1, rmIL-1 R2, rmIL-1 R4, rmIL-1 Rrp2, rmSIGIRR, rhIL-1 R3, rhIL-1 R4, rhIL-1 Rrp2, or rhIL1RAPL1 is observed.
Clonality
Monoclonal
Host
Rat
Isotype
IgG2A
Applications for Mouse IL1RAPL2 Antibody
Application
Recommended Usage
Western Blot
1 µg/mL
Sample: Recombinant Mouse IL1RAPL2
Sample: Recombinant Mouse IL1RAPL2
Formulation, Preparation, and Storage
Purification
Protein A or G purified from hybridoma culture supernatant
Reconstitution
Reconstitute at 0.5 mg/mL in sterile PBS. For liquid material, refer to CoA for concentration.
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Formulation
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
Shipping
Lyophilized product is shipped at ambient temperature. Liquid small pack size (-SP) is shipped with polar packs. Upon receipt, store immediately at the temperature recommended below.
Stability & Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
- 12 months from date of receipt, -20 to -70 °C as supplied.
- 1 month, 2 to 8 °C under sterile conditions after reconstitution.
- 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Calculators
Background: IL1RAPL2
Long Name
Interleukin 1 Receptor Accessory Protein-like 2
Alternate Names
IL-1R10, IL-1RAPL2, IL1RAPL2, TIGIRR-1
Gene Symbol
IL1RAPL2
UniProt
Additional IL1RAPL2 Products
Product Documents for Mouse IL1RAPL2 Antibody
Product Specific Notices for Mouse IL1RAPL2 Antibody
For research use only
Related Research Areas
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Protocols
Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.
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- Troubleshooting Guide: Western Blot Figures
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- Western Blot Troubleshooting Guide
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