Leptin Receptor (Leptin R; LEPR; OB R) is a cytokine receptor for Leptin, a multi-functional hormone that plays roles in food intake, energy metabolism, angiogenesis, reproduction, hematopoiesis, bone metabolism, and immune function. It is primarily expressed in adipose tissue and the hypothalamus and can be released as a soluble molecule. Soluble Leptin R delays the clearance of Leptin from the circulation and is elevated in patients with chronic heart failure, end-stage renal disease, and anorexia. Mutations of Leptin R can cause extreme obesity in humans, mice (db/db), and rats (Zucker fa/fa).
Mouse Leptin R (NP_666258) VersaClone cDNA
R&D Systems | Catalog # RDC2183
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Formulation, Preparation, and Storage
Shipping
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage
Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.
Background: Leptin R
Long Name
Leptin Receptor
Alternate Names
B219, CD295, LEPR, LeptinR, OB R
Gene Symbol
LEPR
UniProt
Additional Leptin R Products
Product Documents for Mouse Leptin R (NP_666258) VersaClone cDNA
Certificate of Analysis
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Product Specific Notices for Mouse Leptin R (NP_666258) VersaClone cDNA
For research use only
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