Meteorin is a 31 kDa, secreted protein that is expressed by undifferentiated neural and glial progenitors, and astrocytes. Its name derives from it ability to generate glial cells with long meteor-like tails. Mouse Meteorin is synthesized as a 291 amino acid (aa) precursor that contains a 270 aa mature region. It contains eight cysteines with no identifiable domains or N-linked glycosylation sites. There is one alternate splice form where the first 164 aa of the precursor are deleted and aa 165 is changed to a Met, possibly to serve in translation initiation. Mature mouse Meteorin is 82% and 77% aa identical to human and bovine Meteorin, respectively.
Key Product Details
Species Reactivity
Mouse
Applications
ELISA Capture (Matched Antibody Pair)
Label
Unconjugated
Antibody Source
Monoclonal Rat IgG2A Clone # 347511
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Product Specifications
Immunogen
Mouse myeloma cell line NS0-derived recombinant mouse Meteorin
Gly22-Asp291
Accession # Q8C1Q4
Gly22-Asp291
Accession # Q8C1Q4
Specificity
Detects mouse Meteorin in ELISAs.In sandwich immunoassays, no cross-reactivity or interference with recombinant mouse CDNF,
recombinant rat (rr) CNTF, or rrGDNF is observed.
Clonality
Monoclonal
Host
Rat
Isotype
IgG2A
Applications for Mouse Meteorin Antibody
Mouse Meteorin Sandwich Immunoassay
Please Note: Optimal dilutions of this antibody should be experimentally determined.
Formulation, Preparation, and Storage
Purification
Protein A or G purified from hybridoma culture supernatant
Reconstitution
Sterile PBS to a final concentration of 0.5 mg/mL. For liquid material, refer to CoA for concentration.
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Formulation
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
Shipping
Lyophilized product is shipped at ambient temperature. Liquid small pack size (-SP) is shipped with polar packs. Upon receipt, store immediately at the temperature recommended below.
Stability & Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
- 12 months from date of receipt, -20 to -70 °C as supplied.
- 1 month, 2 to 8 °C under sterile conditions after reconstitution.
- 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Calculators
Background: Meteorin
Alternate Names
METRN
Gene Symbol
METRN
UniProt
Additional Meteorin Products
Product Documents for Mouse Meteorin Antibody
Certificate of Analysis
To download a Certificate of Analysis, please enter a lot or batch number in the search box below.
Note: Certificate of Analysis not available for kit components.
Product Specific Notices for Mouse Meteorin Antibody
For research use only
Related Research Areas
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