Mouse MS4A4B APC-conjugated Antibody

FAB4504A has been discontinued. View all MS4A4B products.
  
  • Species Reactivity
    Mouse
  • Specificity
    Detects mouse MS4A4B. Stains mouse MS4A4B transfectants but not irrelevant transfectants.
  • Source
    Monoclonal Rat IgG2A Clone # 444008
  • Purification
    Protein A or G purified from hybridoma culture supernatant
  • Immunogen
    HEK293 human embryonic kidney cell line transfected with mouse MS4A4B
    Met1-Val226
    Accession # NP_068364
  • Formulation
    Supplied in a saline solution containing BSA and Sodium Azide.
  • Label
    Allophycocyanin
Applications
  •  
    Recommended
    Concentration
    Sample
  • Flow Cytometry
    10 µL/106 cells
    See below
Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.
Data Examples
Detection of MS4A4B in NS0 Mouse Cell Line by Flow Cytometry. NS0 mouse myeloma cell line transfected with mouse MS4A4B and eGFP was stained with either (A) Rat Anti-Mouse MS4A4B APC‑conjugated Monoclonal Antibody (Catalog # FAB4504A) or (B) Rat IgG2A Allophycocyanin Isotype Control (Catalog # IC006A). View our protocol for Staining Membrane-associated Proteins
Preparation and Storage
  • Shipping
    The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
  • Stability & Storage
    Protect from light. Do not freeze.
    • 12 months from date of receipt, 2 to 8 °C as supplied.
Background: MS4A4B

Membrane Spanning 4 domain family, subfamily A4B (MS4A4B), also known as Chandra, is a member of the MS4A family of four-transmembrane proteins that includes CD20. It is expressed in immature CD4-CD8- T cells, NKT cells, CD4+ and CD8+ T cells, CD4+CD25+FoxP3+ Tregs and later in mature Th1 but not Th2 cells. MS4A4B is enriched in lipid rafts of activated T cells, and overexpression enhances Th1 cytokine expression, indicating a possible role in cell signaling.

  • Long Name:
    Membrane-spanning 4-domains, Subfamily A, Member 4B
  • Entrez Gene IDs:
    60361 (Mouse)
  • Alternate Names:
    AI463180; Chandra; Ly116; MS4A4B
Related Research Areas

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