Mouse/Rat/Chicken Pax6 Biotinylated MAb (Clone PAX6)

Name: Mouse/Rat/Chicken Pax6 Biotinylated MAb (Clone PAX6)
Brand: R&D Systems
SKU: BAM1260

Catalog #: BAM1260
1 Citation Datasheet / COA / SDS

Discontinued Product

BAM1260 has been discontinued.

View all Pax6 products.

All Pax6 Antibodies

Product Details

Citations (1)

FAQs

Reviews

Summary Preparation and Storage Reconstitution Calculator Background Product Datasheets Related Research Areas

Mouse/Rat/Chicken Pax6 Biotinylated MAb (Clone PAX6) Summary

Species Reactivity

Mouse, Rat, Chicken

Specificity

Detects mouse, rat, and chicken Pax6.

Source

Monoclonal Mouse IgG₁ Clone # PAX6

Purification

Protein A or G purified from hybridoma culture supernatant

Immunogen

E. coli-derived recombinant chicken Pax6
aa 1-223

Formulation

Supplied as a 0.2 μm filtered solution in PBS with BSA as a carrier protein.

Endotoxin Level

<0.10 EU per 1 μg of the antibody by the LAL method.

Label

Biotin

Applications

Recommended Concentration

Sample

Immunohistochemistry

8-25 µg/mL

Immersion fixed frozen sections of mouse embryo (E11.5-13.5)

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Reconstitution Calculator

Preparation and Storage

Reconstitution

Reconstitute at 0.5 mg/mL in sterile Tris-buffered saline, pH 7.3 (20 mM Trizma base, 150 mM NaCl) containing 0.1% bovine serum albumin.

Shipping

The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles.

12 months from date of receipt, -20 to -70 °C, as supplied.
1 month, 2 to 8 °C under sterile conditions after opening.
6 months, -20 to -70 °C under sterile conditions after opening.

Background: Pax6

Members of the Pax family of transcription factors contain a paired box DNA binding domain and may or may not contain a paired-type homeodomain and/or octapeptide region. Nine Pax genes have been identified in mammals and are divided into four subgroups based on the sequence elements present. Pax genes play a variety of roles during embryogenesis, regulating cell-lineage specification, proliferation, migration, and survival of diverse cell and tissue types. Several of the Pax genes are also expressed in cancers and serve as tumor markers.

Pax6 is a highly conserved transcription factor essential for the development of tissues including the eyes, central nervous system, and endocrine glands of vertebrates and invertebrates. Pax6 is a key regulator that is required for normal islet development.

Long Name

Paired Box Gene 6

Entrez Gene IDs

5080 (Human); 18508 (Mouse); 25509 (Rat)

Alternate Names

keratitis); MGC17209; Oculorhombin; paired box 6; paired box protein Pax-6; Pax6

Product Datasheets

Product Datasheet

COA

SDS

Related Research Areas

Citation for Mouse/Rat/Chicken Pax6 Biotinylated MAb (Clone PAX6)

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

1 Citation: Showing 1 - 1