Mouse Renin 1 Propeptide Antibody
Mouse Renin 1 Propeptide Antibody Summary
Leu22-Arg402
Accession # P06281
Applications
Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.
Scientific Data
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Renin in Mouse Kidney. Renin was detected in perfusion fixed frozen sections of mouse kidney using 25 µg/mL Rat Anti-Mouse Renin 1 Propeptide Monoclonal Antibody (Catalog # MAB42771) overnight at 4 °C. Tissue was stained (red) and counterstained (green). View our protocol for Fluorescent IHC Staining of Frozen Tissue Sections.
Reconstitution Calculator
Preparation and Storage
- 12 months from date of receipt, -20 to -70 °C as supplied.
- 1 month, 2 to 8 °C under sterile conditions after reconstitution.
- 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Background: Renin
Mouse Renin is a secreted, 42‑47 kDa glycosylated member of the peptidase A1 family. It is an aspartyl protease that cleaves angiotensinogen to form angiotensin I. In mouse, there are two genes that code for Renin. One is in the submandibular gland and the other is in the kidney. The two mature Renin molecules share 95% amino acid (aa) sequence identity. Renal Renin (Renin‑1) is synthesized as a 381 aa proform (aa 22‑402). In the kidney, pro‑Renin is proteolytically cleaved after Thr71 to generate a mature enzyme. Mouse pro‑Renin shares 70% and 85% aa sequence identity with human and rat pro‑Renin, respectively.
Product Datasheets
Citation for Mouse Renin 1 Propeptide Antibody
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.
1 Citation: Showing 1 - 1
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Renin Lineage Cells Repopulate the Glomerular Mesangium after Injury
Authors: Charlotte Starke, Hannah Betz, Linda Hickmann, Peter Lachmann, Björn Neubauer, Jeffrey B. Kopp et al.
Journal of the American Society of Nephrology
Species: Mouse
Sample Types: Whole Tissue
Applications: Immunohistochemistry
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