Key Product Details

Species Reactivity

Mouse

Applications

Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Rat IgG2A Clone # 493804
View all S100A11 Primary Antibodies »

Product Specifications

Immunogen

E. coli-derived recombinant mouse S100A11
Met1-Ile98
Accession # P50543

Specificity

Detects mouse S100A11 in direct ELISAs and Western blots. In direct ELISAs, ;no cross-reactivity with recombinant mouse S100A1, 4, 6, 8, 9, 10, 13, or 16 is observed, and approximately 75% cross‑reactivity with recombinant human (rh) S100A11 is observed. In Western blots, no cross‑reactivity with rhS100A11 is observed

Clonality

Monoclonal

Host

Rat

Isotype

IgG2A

Applications for Mouse S100A11 Antibody

Application
Recommended Usage

Western Blot

1 µg/mL
Sample: Recombinant Mouse S100A11

Formulation, Preparation, and Storage

Purification

Protein A or G purified from hybridoma culture supernatant

Reconstitution

Reconstitute at 0.5 mg/mL in sterile PBS. For liquid material, refer to CoA for concentration.

Formulation

Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.

Shipping

Lyophilized product is shipped at ambient temperature. Liquid small pack size (-SP) is shipped with polar packs. Upon receipt, store immediately at the temperature recommended below.

Stability & Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.

Calculators

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

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Background: S100A11

S100A11, also called calgizzarin or S100C, is an antiproliferative 10 kDa protein that is a member of the S100 family of EF-hand calcium binding proteins. It is found in the cytosol of proliferating fibroblasts and keratinocytes, but in the nucleus in differentiating cells. TGF-beta treatment or calcium-induced S100A11 serine phosphorylation induces nuclear translocation of S100A11 and subsequent growth inhibition in normal cells. The 98 amino acid (aa) mouse S100A11 shares 82% and 94% aa identity with human and rat S100A11, respectively.

Long Name

S100 Calcium Binding Protein A11

Alternate Names

Calgizzarin, MLN70, S100C

Entrez Gene IDs

6282 (Human); 20195 (Mouse); 445415 (Rat)

Gene Symbol

S100A11

UniProt

P50543

Additional S100A11 Products

Product Documents for Mouse S100A11 Antibody

Certificate of Analysis

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Note: Certificate of Analysis not available for kit components.

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Product Specific Notices for Mouse S100A11 Antibody

For research use only

Citations for Mouse S100A11 Antibody

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