Mouse Serpin C1/Antithrombin-III Antibody

Catalog # Availability Size / Price Qty
MAB1287
MAB1287-SP
Product Details
Citations (4)
FAQs
Supplemental Products
Reviews

Mouse Serpin C1/Antithrombin-III Antibody Summary

Species Reactivity
Mouse
Specificity
Detects mouse Serpin C1/Antithrombin-III in direct ELISAs and Western blots. In direct ELISAs and Western blots, 100% cross‑reactivity with recombinant human (rh) Serpin C1 is observed and no cross-reactivity with rhSerpin A1, A3, F2, recombinant mouse Serpin D1 or A5 is observed.
Source
Monoclonal Rat IgG2A Clone # 208730
Purification
Protein A or G purified from hybridoma culture supernatant
Immunogen
Mouse myeloma cell line NS0-derived recombinant mouse Serpin C1/Antithrombin-III
His33-Asn465
Accession # P32261
Formulation
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied as a 0.2 µm filtered solution in PBS.

Applications

Recommended Concentration
Sample
Western Blot
1 µg/mL
Recombinant Mouse Serpin C1/Antithrombin-III

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Reconstitution Calculator

Reconstitution Calculator

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Preparation and Storage

Reconstitution
Reconstitute at 0.5 mg/mL in sterile PBS.
Reconstitution Buffer Available
Reconstitution Buffer 1 (PBS)
Catalog #
Availability
Size / Price
Qty
RB01
Shipping
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. *Small pack size (SP) is shipped with polar packs. Upon receipt, store it immediately at -20 to -70 °C
Stability & Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: Serpin C1/Antithrombin-III

Serpin C1, also called Antithrombin-III, is the principal plasma serpin that inhibits blood clotting proteases such as thrombin and factor Xa.

Entrez Gene IDs
462 (Human); 11905 (Mouse)
Alternate Names
Antithrombin-III; AT3antithrombin-III; ATIII; ATIIIantithrombin III; MGC22579; serine (or cysteine) proteinase inhibitor, clade C (antithrombin), member 1; serine-cysteine proteinase inhibitor clade C member 1; Serpin C1; serpin peptidase inhibitor, clade C (antithrombin), member 1

Product Datasheets

Citations for Mouse Serpin C1/Antithrombin-III Antibody

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

4 Citations: Showing 1 - 4
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  1. Single-domain antibodies targeting antithrombin reduce bleeding in hemophilic mice with or without inhibitors
    Authors: E Barbon, G Ayme, A Mohamadi, JF Ottavi, C Kawecki, C Casari, S Verhenne, S Marmier, L van Witten, S Charles, F Collaud, CV Denis, OD Christophe, F Mingozzi, PJ Lenting
    EMBO Mol Med, 2020;0(0):e11298.
    Species: Human
    Sample Types: Cell Culture Lysates
    Applications: Western Blot
  2. Innate immune responses to TREM-1 activation: overlap, divergence, and positive and negative cross-talk with bacterial lipopolysaccharide.
    Authors: Dower K, Ellis DK, Saraf K, Jelinsky SA, Lin LL
    J. Immunol., 2008;180(5):3520-34.
    Species: Human
    Sample Types: Whole Cells
    Applications: Functional Assay
  3. A soluble form of the triggering receptor expressed on myeloid cells-1 modulates the inflammatory response in murine sepsis.
    Authors: Gibot S, Kolopp-Sarda MN, Bollaert PE, Lozniewski A, Mory F, Levy B, Faure GC
    J. Exp. Med., 2004;200(11):1419-26.
    Species: Human
    Sample Types: Cell Culture Supernates
    Applications: Western Blot
  4. A soluble form of the triggering receptor expressed on myeloid cells-1 modulates the inflammatory response in murine sepsis.
    Authors: Gibot S, Kolopp-Sarda MN, Bollaert PE, Lozniewski A, Mory F, Levy B, Faure GC
    J. Exp. Med., 2004;200(11):1419-26.
    Species: Human
    Sample Types: Cell Culture Supernates
    Applications: Western Blot

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