Mouse VEGF Quantikine ELISA Kit

  (142 citations)
(1 Review)
    
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Product Details
Assay Procedure
Citations (142)
FAQs
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  • Assay Type
    Solid Phase Sandwich ELISA
  • Format
    96-well strip plate
  • Assay Length
    4.5 hours
  • Sample Type & Volume Required Per Well
    Cell Culture Supernates (50 uL), Tissue Homogenates (50 uL), Serum (10 uL), EDTA Plasma (10 uL), Heparin Plasma (10 uL)
  • Sensitivity
    3 pg/mL
  • Assay Range
    7.8 - 500 pg/mL (Cell Culture Supernates, Tissue Homogenates, Serum, EDTA Plasma)
  • Specificity
    This kit recognizes both the 164 and 120 amino acid residue forms of mouse VEGF
  • Cross-reactivity
    < 0.5% cross-reactivity observed with available related molecules.< 50% cross-species reactivity observed with species tested.
  • Interference
    Interference observed with 1 or more available related molecules.
Product Summary
The Quantikine Mouse VEGF Immunoassay is a 4.5 hour solid phase ELISA designed to measure mouse VEGF in cell culture supernates, tissue homogenates, mouse serum, and plasma. It contains Sf 21-expressed mouse VEGF and antibodies raised against the recombinant factor. This immunoassay has been shown to quantitate the recombinant mouse VEGF accurately. Results obtained using natural mouse VEGF showed dose-response curves that were parallel to the standard curves obtained using the recombinant Quantikine kit standards. These results indicate that this kit can be used to determine relative mass values for natural mouse VEGF.

Precision
Intra-Assay Precision (Precision within an assay) Three samples of known concentration were tested on one plate to assess intra-assay precision
Inter-Assay Precision (Precision between assays) Three samples of known concentration were tested in separate assays to assess inter-assay precision
Cell Culture Supernates, Tissue Homogenates, Serum, EDTA Plasma
Intra-Assay Precision Inter-Assay Precision
Sample 1 2 3 1 2 3
n 20 20 20 20 20 20
Mean 37.7 144 277 38.3 138 291
Standard Deviation 3.1 6.2 12.9 3.2 7.8 18.5
CV% 8.2 4.3 4.7 8.4 5.7 6.4

Recovery

The recovery of mouse VEGF spiked to three levels throughout the range of the assay in various matrices was evaluated.

Sample Type Average % Recovery Range %
Cell Culture Supernates (n=9) 103 95-114
EDTA Plasma (n=5) 91 82-103
Heparin Plasma (n=4) 89 87-94
Serum (n=9) 101 83-115
Tissue Homogenates (n=3) 91 76-107
Linearity
To assess the linearity of the assay, samples containing and/or spiked with various concentrations of mouse VEGF in each matrix were diluted with Calibrator Diluent and then assayed.
 VEGF [HRP]
Product Datasheets

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Preparation and Storage
  • Storage
    Store the unopened product at 2 - 8 °C. Do not use past expiration date.
Background: VEGF
VEGF (Vascular endothelial growth factor) is a potent mediator of both angiogenesis and vasculogenesis in the fetus and adult. It is required for regulating the proliferation, migration, and survival of embryonic endothelial cells and during wound healing and the female reproductive cycle in adults. Pathologically, it is involved in tumor development and tumor vascular leakage. VEGF binds to VEGF R1/Flt-1, VEGF R2/Flk-1/KDR, and Neuropilin-1. Multiple forms of VEGF are generated by alternative splicing and proteolysis.
  • Long Name:
    Vascular Endothelial Growth Factor
  • Entrez Gene IDs:
    7422 (Human); 22339 (Mouse); 83785 (Rat); 281572 (Bovine); 403802 (Canine); 493845 (Feline); 30682 (Zebrafish)
  • Alternate Names:
    MVCD1; VAS; vascular endothelial growth factor A; Vascular permeability factor; Vasculotropin; VEGF; VEGFA; VEGF-A; VEGFMGC70609; VPF; VPFvascular endothelial growth factor
Related Research Areas
Assay Procedure
Refer to the product for complete assay procedure.

Bring all reagents and samples to room temperature before use. It is recommended that all samples, standards, and controls be assayed in duplicate.
  1.   Prepare all reagents, standard dilutions, and samples as directed in the product insert.
  2.   Remove excess microplate strips from the plate frame, return them to the foil pouch containing the desiccant pack, and reseal.

  3. 50 µL Assay Diluent
  4.   Add 50 µL of Assay Diluent to each well.

  5. 50 µL Standard, Control, or Sample
  6.   Add 50 µL of Standard, Control, or sample to each well. Cover with a plate sealer, and incubate at room temperature for 2 hours.
  7.   Aspirate each well and wash, repeating the process 4 times for a total of 5 washes.

  8. 100 µL Conjugate
  9.   Add 100 µL of Conjugate to each well. Cover with a new plate sealer, and incubate at room temperature for 2 hours.
  10.   Aspirate and wash 5 times.

  11. 100 µL Substrate Solution
  12.   Add 100 µL Substrate Solution to each well. Incubate at room temperature for 30 minutes. PROTECT FROM LIGHT.

  13. 100 µL Stop Solution
  14.   Add 100 µL of Stop Solution to each well. Read at 450 nm within 30 minutes. Set wavelength correction to 540 nm or 570 nm.
Citations:

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

142 Citations: Showing 1 - 10
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Species
Sample Type
  1. Tumor-independent host secretomes induced by angiogenesis and immune-checkpoint inhibitors
    Authors: M Mastri, CR Lee, A Tracz, RS Kerbel, M Dolan, Y Shi, JML Ebos
    Mol. Cancer Ther., 2018;0(0):.
    Species: Mouse
    Sample Type: Plasma
  2. Bevacizumab Promotes T-Cell-Mediated Collagen Deposition in the Mouse Model of Conjunctival Scarring
    Authors: LF Seet, LZ Toh, S Chu, SN Finger, F Ginhoux, W Hong, TT Wong
    Invest. Ophthalmol. Vis. Sci., 2018;59(3):1682-1692.
    Species: Mouse
    Sample Type: Tissue Homogenates
  3. Potential benefits of mesenchymal stem cells and electroacupuncture on the trophic factors associated with neurogenesis in mice with ischemic stroke
    Authors: YR Kim, SM Ahn, ME Pak, HJ Lee, DH Jung, YI Shin, HK Shin, BT Choi
    Sci Rep, 2018;8(1):2044.
    Species: Mouse
    Sample Type: Tissue Homogenates
  4. Intermittent hypoxia increases kidney tumor vascularization in a murine model of sleep apnea
    Authors: A Vilaseca, N Campillo, M Torres, M Musquera, D Gozal, JM Montserrat, A Alcaraz, KA Touijer, R Farré, I Almendros
    PLoS ONE, 2017;12(6):e0179444.
    Species: Mouse
    Sample Type: Plasma
  5. Acute and Chronic Sustained Hypoxia Do Not Substantially Regulate Amyloid-? Peptide Generation In Vivo
    Authors: A Serrano-Po, MA S nchez-Ga, A Heras-Garv, R March-D¡az, V Navarro, M Vizuete, J L¢pez-Barn, J Vitorica, A Pascual
    PLoS ONE, 2017;12(1):e0170345.
    Species: Mouse
    Sample Type: Tissue Homogenates
  6. In vivo genome editing with a small Cas9 orthologue derived from Campylobacter jejuni
    Authors: E Kim, T Koo, SW Park, D Kim, K Kim, HY Cho, DW Song, KJ Lee, MH Jung, S Kim, JH Kim, JH Kim, JS Kim
    Nat Commun, 2017;8(0):14500.
    Species: Mouse
    Sample Type: Tissue Homogenates
  7. ANG1 treatment reduces muscle pathology and prevents a decline in perfusion in DMD mice
    Authors: KM Gutpell, N Tasevski, B Wong, WT Hrinivich, F Su, J Hadway, L Desjardins, TY Lee, LM Hoffman
    PLoS ONE, 2017;12(3):e0174315.
    Species: Mouse
    Sample Type: Tissue Homogenates
  8. Motor neurons control blood vessel patterning in the developing spinal cord
    Authors: P Himmels, I Paredes, H Adler, A Karakatsan, R Luck, HH Marti, O Ermakova, E Rempel, ET Stoeckli, C Ruiz de Al
    Nat Commun, 2017;8(0):14583.
    Species: Mouse
    Sample Type: Tissue Homogenates
  9. Experimental Anterior Ischemic Optic Neuropathy in Diabetic Mice Exhibited Severe Retinal Swelling Associated With VEGF Elevation
    Authors: MH Sun, MA Shariati, YJ Liao
    Invest. Ophthalmol. Vis. Sci., 2017;58(4):2296-2305.
    Species: Mouse
    Sample Type: Serum
  10. CXCL1 is critical for pre-metastatic niche formation and metastasis in colorectal cancer
    Authors: D Wang, H Sun, J Wei, B Cen, RN DuBois
    Cancer Res., 2017;0(0):.
    Species: Mouse
    Sample Type: Tissue Homogenates
  11. Interactions between fibroblastic reticular cells and B cells promote mesenteric lymph node lymphangiogenesis
    Authors: L Kumar Dube, P Karempudi, SA Luther, B Ludewig, NL Harris
    Nat Commun, 2017;8(1):367.
    Species: Mouse
    Sample Type: Cell Culture Supernates
  12. Vascular Endothelial Growth Factor in Cartilage Development and Osteoarthritis
    Authors: M Nagao, JL Hamilton, R Kc, AD Berendsen, X Duan, CW Cheong, X Li, HJ Im, BR Olsen
    Sci Rep, 2017;7(1):13027.
    Species: Mouse
    Sample Type: Cell Culture Supernates
  13. Induction of erythropoiesis by hypoxia-inducible factor prolyl hydroxylase inhibitors without promotion of tumor initiation, progression, or metastasis in a VEGF-sensitive model of spontaneous breast cancer
    Authors: TW Seeley, MD Sternlicht, SJ Klaus, TB Neff, DY Liu
    Hypoxia (Auckl), 2017;5(0):1-9.
    Species: Mouse
    Sample Type: Plasma
  14. Monocyte chemotactic protein-1 deficiency reduces spontaneous metastasis of Lewis lung carcinoma in mice fed a high-fat diet
    Oncotarget, 2016;7(17):24792-9.
    Species: Mouse
    Sample Type: Plasma
  15. Exercise-like effects by Estrogen-related receptor-gamma in muscle do not prevent insulin resistance in db/db mice
    Sci Rep, 2016;6(0):26442.
    Species: Mouse
    Sample Type: Tissue Homogenates
  16. Discontinuation of anti-VEGF cancer therapy promotes metastasis through a liver revascularization mechanism
    Nat Commun, 2016;7(0):12680.
    Species: Mouse
    Sample Type: Tissue Homogenates
  17. First steps to define murine amniotic fluid stem cell microenvironment
    Sci Rep, 2016;6(0):37080.
    Species: Mouse
    Sample Type: Amniotic Fluid
  18. Comparative systems pharmacology of HIF stabilization in the prevention of retinopathy of prematurity
    Authors: G Hoppe, S Yoon, B Gopalan, AR Savage, R Brown, K Case, A Vasanji, ER Chan, RB Silver, JE Sears
    Proc Natl Acad Sci USA, 2016;0(0):.
    Species: Mouse
    Sample Type: Serum
  19. Excess HB-EGF, which promotes VEGF signaling, leads to hydrocephalus
    Authors: Joon W Shim
    Sci Rep, 2016;6(0):26794.
  20. Endothelial PDGF-CC regulates angiogenesis-dependent thermogenesis in beige fat
    Nat Commun, 2016;7(0):12152.
    Species: Mouse
    Sample Type: Tissue Homogenates
  21. Hyperoxia-Induced Proliferative Retinopathy: Early Interruption of Retinal Vascular Development with Severe and Irreversible Neurovascular Disruption
    PLoS ONE, 2016;11(11):e0166886.
    Species: Mouse
    Sample Type: Tissue Homogenates
  22. Stimulation of endogenous cardioblasts by exogenous cell therapy after myocardial infarction.
    Authors: Malliaras K, Ibrahim A, Tseliou E, Liu W, Sun B, Middleton R, Seinfeld J, Wang L, Sharifi B, Marban E
    EMBO Mol Med, 2016;6(6):760-77.
    Species: Mouse
    Sample Type: Cell Culture Supernates
  23. Retinal lipid and glucose metabolism dictates angiogenesis through the lipid sensor Ffar1
    Nat. Med., 2016;22(4):439-45.
    Species: Mouse
    Sample Type: Tissue Homogenates
  24. The biomechanical properties of an epithelial tissue determine the location of its vasculature
    Nat Commun, 2016;7(0):13560.
    Species: Mouse
    Sample Type: Cell Culture Supernates
  25. Association of Heme Oxygenase 1 with Lung Protection in Malaria-Associated ALI/ARDS
    Authors: Marcelo L M Pereira
    Mediators Inflamm, 2016;2016(0):4158698.
    Species: Mouse
    Sample Type: Serum
  26. Exercise restores muscle stem cell mobilization, regenerative capacity and muscle metabolic alterations via adiponectin/AdipoR1 activation in SAMP10 mice
    Authors: Aiko Inoue
    J Cachexia Sarcopenia Muscle, 2016;0(0):.
    Species: Mouse
    Sample Type: Plasma
  27. Modulation of VEGF signaling in a mouse model of diabetes by xanthohumol and 8-prenylnaringenin: Unveiling the angiogenic paradox and metabolism interplay
    Authors: Raquel Costa
    Mol Nutr Food Res, 2016;0(0):.
    Species: Mouse
    Sample Type: Plasma
  28. Renin-Angiotensin System Transgenic Mouse Model Recapitulates Pathophysiology Similar to Human Preeclampsia with Renal Injury that may be Mediated through VEGF
    Authors: J Morgan Denney
    Am. J. Physiol. Renal Physiol, 2016;0(0):ajprenal.0010.
    Species: Mouse
    Sample Type: Plasma
  29. Perivascular M2 Macrophages Stimulate Tumor Relapse after Chemotherapy.
    Authors: Hughes R, Qian B, Rowan C, Muthana M, Keklikoglou I, Olson O, Tazzyman S, Danson S, Addison C, Clemons M, Gonzalez-Angulo A, Joyce J, De Palma M, Pollard J, Lewis C
    Cancer Res, 2015;75(17):3479-91.
    Species: Mouse
    Sample Type: Cell Culture Supernates
  30. Investigation of retinal morphology alterations using spectral domain optical coherence tomography in a mouse model of retinal branch and central retinal vein occlusion.
    Authors: Ebneter, Andreas, Agca, Cavit, Dysli, Chantal, Zinkernagel, Martin S
    PLoS ONE, 2015;10(3):e0119046.
    Species: Mouse
    Sample Type: Tissue Homogenates
  31. Gain of HIF-1alpha under normoxia in cancer mediates immune adaptation through the AKT/ERK and VEGFA axes.
    Authors: Lee Y, Bae H, Noh K, Song K, Ye S, Mao C, Lee K, Wu T, Kim T
    Clin Cancer Res, 2015;21(6):1438-46.
    Species: Mouse
    Sample Type: Cell Culture Supernates
  32. Accelerated tumor progression in mice lacking the ATP receptor P2X7.
    Authors: Adinolfi E, Capece M, Franceschini A, Falzoni S, Giuliani A, Rotondo A, Sarti A, Bonora M, Syberg S, Corigliano D, Pinton P, Jorgensen N, Abelli L, Emionite L, Raffaghello L, Pistoia V, Di Virgilio F
    Cancer Res, 2015;75(4):635-44.
    Species: Mouse
    Sample Type: Cell Culture Supernates
  33. Microangiopathy triggers, and inducible nitric oxide synthase exacerbates dextran sulfate sodium-induced colitis.
    Authors: Saijo H, Tatsumi N, Arihiro S, Kato T, Okabe M, Tajiri H, Hashimoto H
    Lab Invest, 2015;95(7):728-48.
    Species: Mouse
    Sample Type: Serum
  34. Neutrophil Depletion Attenuates Placental Ischemia-Induced Hypertension in the Rat.
    Authors: Regal J, Lillegard K, Bauer A, Elmquist B, Loeks-Johnson A, Gilbert J
    PLoS ONE, 2015;10(7):e0132063.
    Species: Rat
    Sample Type: Plasma
  35. Rac1 Regulates Endometrial Secretory Function to Control Placental Development.
    Authors: Davila J, Laws M, Kannan A, Li Q, Taylor R, Bagchi M, Bagchi I
    PLoS Genet, 2015;11(8):e1005458.
    Species: Mouse
    Sample Type: Cell Culture Supernates
  36. Regulated in development and DNA damage 1 is necessary for hyperglycemia-induced vascular endothelial growth factor expression in the retina of diabetic rodents.
    Authors: Dennis M, Kimball S, Fort P, Jefferson L
    J Biol Chem, 2015;290(6):3865-74.
    Species: Mouse
    Sample Type: Cell Culture Supernates
  37. Conditioned media from adipose stromal cells limit lipopolysaccharide-induced lung injury, endothelial hyperpermeability and apoptosis.
    Authors: Lu H, Poirier C, Cook T, Traktuev D, Merfeld-Clauss S, Lease B, Petrache I, March K, Bogatcheva N
    J Transl Med, 2015;13(0):67.
    Species: Mouse
    Sample Type: BALF
  38. Anti-angiogenic effect of metformin in mouse oxygen-induced retinopathy is mediated by reducing levels of the vascular endothelial growth factor receptor Flk-1.
    Authors: Joe, Soo Geun, Yoon, Young He, Choi, Jeong A, Koh, Jae-Youn
    PLoS ONE, 2015;10(3):e0119708.
    Species: Mouse
    Sample Type: Tissue Homogenates
  39. The Immune Interplay between Thyroid Papillary Carcinoma and Hepatic Fibrosis.
    Authors: Muhanna N, Amer J, Salhab A, Sichel J, Safadi R
    PLoS ONE, 2015;10(7):e0132463.
    Species: Mouse
    Sample Type: Serum
  40. Advances in the pathophysiology of pre-eclampsia and related podocyte injury.
    Authors: Craici, Iasmina, Wagner, Steven J, Weissgerber, Tracey L, Grande, Joseph P, Garovic, Vesna D
    Kidney Int, 2014;86(2):275-85.
    Species: Rat
    Sample Type:
  41. Epigenetic upregulation of endogenous VEGF-A reduces myocardial infarct size in mice.
    Authors: Turunen M, Husso T, Musthafa H, Laidinen S, Dragneva G, Laham-Karam N, Honkanen S, Paakinaho A, Laakkonen J, Gao E, Vihinen-Ranta M, Liimatainen T, Yla-Herttuala S
    PLoS ONE, 2014;9(2):e89979.
    Species: Mouse
    Sample Type: Tissue Homogenates
  42. Mitigation of oxygen-induced retinopathy in alpha2beta1 integrin-deficient mice.
    Authors: Madamanchi A, Capozzi M, Geng L, Li Z, Friedman R, Dickeson S, Penn J, Zutter M
    Invest Ophthalmol Vis Sci, 2014;55(7):4338-47.
    Species: Mouse
    Sample Type: Cell Culture Supernates
  43. Sonic hedgehog gene therapy increases the ability of the dystrophic skeletal muscle to regenerate after injury.
    Authors: Piccioni A, Gaetani E, Palladino M, Gatto I, Smith R, Neri V, Marcantoni M, Giarretta I, Silver M, Straino S, Capogrossi M, Landolfi R, Pola R
    Gene Ther, 2014;21(4):413-21.
    Species: Mouse
    Sample Type: Cell Culture Supernates
  44. Alcohol promotes mammary tumor growth through activation of VEGF-dependent tumor angiogenesis.
    Authors: Lu, Yanmin, Ni, Fang, Xu, Mei, Yang, Jinlian, Chen, Ji, Chen, Zhuo, Wang, Xinyi, Luo, Jia, Wang, Siying
    Oncol Lett, 2014;8(2):673-678.
    Species: Mouse
    Sample Type: Cell Culture Supernates
  45. Diabetes irreversibly depletes bone marrow-derived mesenchymal progenitor cell subpopulations.
    Authors: Januszyk M, Sorkin M, Glotzbach J, Vial I, Maan Z, Rennert R, Duscher D, Thangarajah H, Longaker M, Butte A, Gurtner G
    Diabetes, 2014;63(9):3047-56.
    Species: Mouse
    Sample Type: Cell Culture Supernates
  46. Capillary force seeding of hydrogels for adipose-derived stem cell delivery in wounds.
    Authors: Garg R, Rennert R, Duscher D, Sorkin M, Kosaraju R, Auerbach L, Lennon J, Chung M, Paik K, Nimpf J, Rajadas J, Longaker M, Gurtner G
    Stem Cells Transl Med, 2014;3(9):1079-89.
    Species: Mouse
    Sample Type: Protein
  47. Long-chain fatty acid analogues suppress breast tumorigenesis and progression.
    Authors: Gluschnaider U, Hertz R, Ohayon S, Smeir E, Smets M, Pikarsky E, Bar-Tana J
    Cancer Res, 2014;74(23):6991-7002.
    Species: Mouse
    Sample Type: Tissue Homogenates
  48. Inflammation induced by MMP-9 enhances tumor regression of experimental breast cancer.
    Authors: Leifler K, Svensson S, Abrahamsson A, Bendrik C, Robertson J, Gauldie J, Olsson A, Dabrosin C
    J Immunol, 2013;190(8):4420-30.
    Species: Mouse
    Sample Type: Tissue Homogenates
  49. Suppression of laser-induced choroidal neovascularization by a CCR3 antagonist.
    Authors: Mizutani, Takeshi, Ashikari, Masayuki, Tokoro, Mayumi, Nozaki, Miho, Ogura, Yuichiro
    Invest Ophthalmol Vis Sci, 2013;54(2):1564-72.
    Species: Mouse
    Sample Type: Cell Culture Supernates
  50. Anthocyanin-rich purple corn extract inhibit diabetes-associated glomerular angiogenesis.
    Authors: Kang M, Lim S, Lee J, Yeo K, Kang Y
    PLoS ONE, 2013;8(11):e79823.
    Species: Mouse
    Sample Type: Plasma
  51. Cilostazol improves the response to ischemia in diabetic mice by a mechanism dependent on PPARgamma.
    Authors: Biscetti F, Pecorini G, Arena V, Stigliano E, Angelini F, Ghirlanda G, Ferraccioli G, Flex A
    Mol Cell Endocrinol, 2013;381(1):80-7.
    Species: Mouse
    Sample Type: Tissue Homogenates
  52. mTORC1 and mTORC2 play different roles in the functional survival of transplanted adipose-derived stromal cells in hind limb ischemic mice via regulating inflammation in vivo.
    Authors: Fan W, Cheng K, Qin X, Narsinh K, Wang S, Hu S, Wang Y, Chen Y, Wu J, Xiong L, Cao F
    Stem Cells, 2013;31(1):203-14.
    Species: Mouse
    Sample Type: Tissue Homogenates
  53. The impact of KRAS mutations on VEGF-A production and tumour vascular network.
    Authors: Figueras A, Arbos M, Quiles M, Vinals F, Germa J, Capella G
    BMC Cancer, 2013;13(0):125.
    Species: Mouse
    Sample Type: Cell Culture Supernates
  54. Matrix protein of vesicular stomatitis virus: a potent inhibitor of vascular endothelial growth factor and malignant ascites formation.
    Authors: Zhou Y, Wen F, Zhang P, Tang R, Li Q
    Cancer Gene Ther, 2013;20(3):178-85.
    Species: Mouse
    Sample Type: Plasma
  55. Transplantation of mesenchymal cells rejuvenated by the overexpression of telomerase and myocardin promotes revascularization and tissue repair in a murine model of hindlimb ischemia.
    Authors: Madonna R, Taylor D, Geng Y, De Caterina R, Shelat H, Perin E, Willerson J
    Circ Res, 2013;113(7):902-14.
    Species: Mouse
    Sample Type: Cell Culture Supernates
  56. Apricoxib, a novel inhibitor of COX-2, markedly improves standard therapy response in molecularly defined models of pancreatic cancer.
    Clin. Cancer Res., 2012;18(18):5031-42.
    Species: Mouse
    Sample Type: Plasma
  57. Guanylate-binding protein 1 expression from embryonal endothelial progenitor cells reduces blood vessel density and cellular apoptosis in an axially vascularised tissue-engineered construct.
    Authors: Bleiziffer O, Hammon M, Arkudas A, Taeger C, Beier J, Amann K, Naschberger E, Sturzl M, Horch R, Kneser U
    BMC Biotechnol, 2012;12(0):94.
    Species: Mouse
    Sample Type: Cell Culture Supernates
  58. Hypoxia-inducible Factor-1 (HIF-1) but Not HIF-2 Is Essential for Hypoxic Induction of Collagen Prolyl 4-Hydroxylases in Primary Newborn Mouse Epiphyseal Growth Plate Chondrocytes.
    Authors: Aro E, Khatri R
    J. Biol. Chem., 2012;287(44):37134-44.
    Species: Mouse
    Sample Type: Cell Culture Supernates
  59. TIEG1 inhibits breast cancer invasion and metastasis by inhibition of epidermal growth factor receptor (EGFR) transcription and the EGFR signaling pathway.
    Authors: Jin W, Chen BB, Li JY, Zhu H, Huang M, Gu SM, Wang QQ, Chen JY, Yu S, Wu J, Shao ZM
    Mol. Cell. Biol., 2012;32(1):50-63.
    Species: Mouse
    Sample Type: Serum
  60. Inhibitory effect of the combination therapy of simvastatin and pinocembrin on atherosclerosis in ApoE-deficient mice.
    Authors: Sang, Hui, Yuan, Na, Yao, Shutong, Li, Furong, Wang, Jiafu, Fang, Yongqi, Qin, Shucun
    Lipids Health Dis, 2012;11(0):166.
    Species: Mouse
    Sample Type: Serum
  61. Antimycotic ciclopirox olamine in the diabetic environment promotes angiogenesis and enhances wound healing.
    Authors: Ko SH, Nauta A, Morrison SD, Zhou H, Zimmermann A, Gurtner GC, Ding S, Longaker MT
    PLoS ONE, 2011;6(11):e27844.
    Species: Mouse
    Sample Type: Cell Culture Supernates
  62. Ocular neovascularization caused by herpes simplex virus type 1 infection results from breakdown of binding between vascular endothelial growth factor A and its soluble receptor.
    Authors: Suryawanshi A, Mulik S, Sharma S
    J. Immunol., 2011;186(6):3653-65.
    Species: Mouse
    Sample Type: Tissue Homogenates
  63. Conditional HIF-1 induction produces multistage neovascularization with stage-specific sensitivity to VEGFR inhibitors and myeloid cell independence.
    Authors: Oladipupo SS, Hu S, Santeford AC, Yao J, Kovalski JR, Shohet RV, Maslov K, Wang LV, Arbeit JM
    Blood, 2011;117(15):4142-53.
    Species: Human
    Sample Type: Plasma
  64. HIF-VEGF pathways are critical for chronic otitis media in Junbo and Jeff mouse mutants.
    Authors: Cheeseman MT, Tyrer HE, Williams D, Hough TA, Pathak P, Romero MR, Hilton H, Bali S, Parker A, Vizor L, Purnell T, Vowell K, Wells S, Bhutta MF, Potter PK, Brown SD
    PLoS Genet., 2011;7(10):e1002336.
    Species: Mouse
    Sample Type: Serum
  65. Relationship between complement membrane attack complex, chemokine (C-C motif) ligand 2 (CCL2) and vascular endothelial growth factor in mouse model of laser-induced choroidal neovascularization.
    Authors: Liu J, Jha P, Lyzogubov VV, Tytarenko RG, Bora NS, Bora PS
    J. Biol. Chem., 2011;286(23):20991-1001.
    Species: Mouse
    Sample Type: Tissue Homogenates
  66. Transgenic expression of human cathepsin B promotes progression and metastasis of polyoma-middle-T-induced breast cancer in mice.
    Authors: Sevenich L, Werner F, Gajda M, Schurigt U, Sieber C, Muller S, Follo M, Peters C, Reinheckel T
    Oncogene, 2011;30(1):54-64.
    Species: Mouse
    Sample Type: Tissue Homogenates
  67. IL-17 and VEGF are necessary for efficient corneal nerve regeneration.
    Authors: Li Z, Burns AR, Han L, Rumbaut RE, Smith CW
    Am. J. Pathol., 2011;178(3):1106-16.
    Species: Mouse
    Sample Type: Tissue Homogenates
  68. Small-molecule inhibitors of vascular adhesion protein-1 reduce the accumulation of myeloid cells into tumors and attenuate tumor growth in mice.
    Authors: Marttila-Ichihara F, Castermans K, Auvinen K, oude Egbrink MG, Jalkanen S, Griffioen AW, Salmi M
    J. Immunol., 2010;184(6):3164-73.
    Species: Mouse
    Sample Type: Serum
  69. Functions of type II pneumocyte-derived vascular endothelial growth factor in alveolar structure, acute inflammation, and vascular permeability.
    Authors: Mura M, Binnie M, Han B, Li C, Andrade CF, Shiozaki A, Zhang Y, Ferrara N, Hwang D, Waddell TK, Keshavjee S, Liu M
    Am. J. Pathol., 2010;176(4):1725-34.
    Species: Mouse
    Sample Type: BALF
  70. Cationic liposome coupled endostatin gene for treatment of peritoneal colon cancer.
    Authors: Lan KL, Ou-Yang F, Yen SH, Shih HL, Lan KH
    Clin. Exp. Metastasis, 2010;27(5):307-18.
    Species: Mouse
    Sample Type: Peritoneal Lavage
  71. Platelet-derived growth factor-B normalizes micromorphology and vessel function in vascular endothelial growth factor-A-induced squamous cell carcinomas.
    Authors: Lederle W, Linde N, Heusel J, Bzyl J, Woenne EC, Zwick S, Skobe M, Kiessling F, Fusenig NE, Mueller MM
    Am. J. Pathol., 2010;176(2):981-94.
    Species: Mouse
    Sample Type: Cell Culture Supernates
  72. Effect of aromatase inhibitors on ectopic endometrial growth and peritoneal environment in a mouse model of endometriosis.
    Authors: Bilotas M, Meresman G, Stella I, Sueldo C, Baranao RI
    Fertil. Steril., 2010;93(8):2513-8.
    Species: Mouse
    Sample Type: Peritoneal Fluid
  73. Placental growth factor mediates aldosterone-dependent vascular injury in mice.
    Authors: Jaffe IZ, Newfell BG, Aronovitz M
    J. Clin. Invest., 2010;120(11):3891-900.
    Species: Mouse
    Sample Type: Tissue Homogenates
  74. Inhibition of EGFR pathway signaling and the metastatic potential of breast cancer cells by PA-MSHA mediated by type 1 fimbriae via a mannose-dependent manner.
    Authors: Liu ZB, Hou YF, Zhu J
    Oncogene, 2010;29(20):2996-3009.
    Species: Mouse
    Sample Type: Serum
  75. Regulation of pathologic retinal angiogenesis in mice and inhibition of VEGF-VEGFR2 binding by soluble heparan sulfate.
    Authors: Nishiguchi KM, Kataoka K, Kachi S
    PLoS ONE, 2010;5(10):e13493.
    Species: Mouse
    Sample Type: Aqueous Humor
  76. Hydroxylase inhibition abrogates TNF-alpha-induced intestinal epithelial damage by hypoxia-inducible factor-1-dependent repression of FADD.
    Authors: Hindryckx P, De Vos M, Jacques P, Ferdinande L, Peeters H, Olievier K, Bogaert S, Brinkman B, Vandenabeele P, Elewaut D, Laukens D
    J. Immunol., 2010;185(10):6306-16.
    Species: Mouse
    Sample Type: Cell Culture Supernates
  77. Varying susceptibility of pulmonary cytokine production to lipopolysaccharide in mice.
    Authors: Alm AS, Li K, Yang D, Andersson R, Lu Y, Wang X
    Cytokine, 2010;49(3):256-63.
    Species: Mouse
    Sample Type: BALF
  78. Matrix-binding vascular endothelial growth factor (VEGF) isoforms guide granule cell migration in the cerebellum via VEGF receptor Flk1.
    Authors: Ruiz de Almodovar C, Coulon C, Salin PA, Knevels E, Chounlamountri N, Poesen K, Hermans K, Lambrechts D, Van Geyte K, Dhondt J, Dresselaers T, Renaud J, Aragones J, Zacchigna S, Geudens I, Gall D, Stroobants S, Mutin M, Dassonville K, Storkebaum E, Jordan BF, Eriksson U, Moons L, D'Hooge R, Haigh JJ, Belin MF, Schiffmann S, Van Hecke P, Gallez B, Vinckier S, Chedotal A, Honnorat J, Thomasset N, Carmeliet P, Meissirel C
    J. Neurosci., 2010;30(45):15052-66.
    Species: Mouse
    Sample Type: Tissue Homogenates
  79. Inhibitory effect of atractylenolide I on angiogenesis in chronic inflammation in vivo and in vitro.
    Authors: Wang C, Duan H, He L
    Eur. J. Pharmacol., 2009;612(1):143-52.
    Species: Mouse
    Sample Type: Air Pouch Exudate
  80. Role of Tim-3/galectin-9 inhibitory interaction in viral-induced immunopathology: shifting the balance toward regulators.
    Authors: Sehrawat S, Suryawanshi A, Hirashima M, Rouse BT
    J. Immunol., 2009;182(5):3191-201.
    Species: Mouse
    Sample Type: Tissue Homogenates
  81. Effects of increased renal tubular vascular endothelial growth factor (VEGF) on fibrosis, cyst formation, and glomerular disease.
    Authors: Hakroush S, Moeller MJ, Theilig F, Kaissling B, Sijmonsma TP, Jugold M, Akeson AL, Traykova-Brauch M, Hosser H, Hahnel B, Grone HJ, Koesters R, Kriz W
    Am. J. Pathol., 2009;175(5):1883-95.
    Species: Mouse
    Sample Type: Serum
  82. Kallidinogenase normalizes retinal vasopermeability in streptozotocin-induced diabetic rats: potential roles of vascular endothelial growth factor and nitric oxide.
    Authors: Kato N, Hou Y, Lu Z, Lu C, Nagano H, Suzuma K, Takagi H, Matsumoto Y
    Eur. J. Pharmacol., 2009;606(1):187-90.
    Species: Mouse
    Sample Type: Aqueous Humor
  83. Disruption of interleukin-1 signaling improves the quality of wound healing.
    Authors: Thomay AA, Daley JM, Sabo E, Worth PJ, Shelton LJ, Harty MW, Reichner JS, Albina JE
    Am. J. Pathol., 2009;174(6):2129-36.
    Species: Mouse
    Sample Type: Tissue Secretion
  84. Recapitulation of pancreatic neuroendocrine tumors in human multiple endocrine neoplasia type I syndrome via Pdx1-directed inactivation of Men1.
    Authors: Shen HC, He M, Powell A, Adem A, Lorang D, Heller C, Grover AC, Ylaya K, Hewitt SM, Marx SJ, Spiegel AM, Libutti SK
    Cancer Res., 2009;69(5):1858-66.
    Species: Mouse
    Sample Type: Tissue Homogenates
  85. The Down syndrome critical region gene 1 short variant promoters direct vascular bed-specific gene expression during inflammation in mice.
    Authors: Minami T, Yano K, Miura M, Kobayashi M, Suehiro J, Reid PC, Hamakubo T, Ryeom S, Aird WC, Kodama T
    J. Clin. Invest., 2009;119(8):2257-70.
    Species: Mouse
    Sample Type: Plasma
  86. Short-term effects of pharmacologic HIF stabilization on vasoactive and cytotrophic factors in developing mouse brain.
    Authors: Schneider C, Krischke G, Keller S, Walkinshaw G, Arend M, Rascher W, Gassmann M, Trollmann R
    Brain Res., 2009;1280(0):43-51.
    Species: Mouse
    Sample Type: Serum
  87. Chemokine receptor CX3CR1 mediates skin wound healing by promoting macrophage and fibroblast accumulation and function.
    Authors: Ishida Y, Gao JL, Murphy PM
    J. Immunol., 2008;180(1):569-79.
    Species: Mouse
    Sample Type: Tissue Homogenates
  88. (Pro)renin receptor promotes choroidal neovascularization by activating its signal transduction and tissue renin-angiotensin system.
    Authors: Satofuka S, Ichihara A, Nagai N, Noda K, Ozawa Y, Fukamizu A, Tsubota K, Itoh H, Oike Y, Ishida S
    Am. J. Pathol., 2008;173(6):1911-8.
    Species: Mouse
    Sample Type: Tissue Homogenates
  89. The aryl hydrocarbon receptor (AhR) inhibits vanadate-induced vascular endothelial growth factor (VEGF) production in TRAMP prostates.
    Authors: Fritz WA, Lin TM, Peterson RE
    Carcinogenesis, 2008;29(5):1077-82.
    Species: Mouse
    Sample Type: Tissue Homogenates
  90. An Adam15 amplification loop promotes vascular endothelial growth factor-induced ocular neovascularization.
    Authors: Xie B, Shen J, Dong A, Swaim M, Hackett SF, Wyder L, Worpenberg S, Barbieri S, Campochiaro PA
    FASEB J., 2008;22(8):2775-83.
    Species: Mouse
    Sample Type: Tissue Homogenates
  91. Rapid chemotherapy-induced acute endothelial progenitor cell mobilization: implications for antiangiogenic drugs as chemosensitizing agents.
    Authors: Shaked Y, Henke E, Roodhart JM, Mancuso P, Langenberg MH, Colleoni M, Daenen LG, Man S, Xu P, Emmenegger U, Tang T, Zhu Z, Witte L, Strieter RM, Bertolini F, Voest EE, Benezra R, Kerbel RS
    Cancer Cell, 2008;14(3):263-73.
    Species: Mouse
    Sample Type: Plasma
  92. MicroRNAs regulate ocular neovascularization.
    Authors: Shen J, Yang X, Xie B, Chen Y, Swaim M, Hackett SF, Campochiaro PA
    Mol. Ther., 2008;16(7):1208-16.
    Species: Mouse
    Sample Type: Tissue Homogenates
  93. Regulation of scar formation by vascular endothelial growth factor.
    Authors: Wilgus TA, Ferreira AM, Oberyszyn TM, Bergdall VK, DiPietro LA
    Lab. Invest., 2008;88(6):579-90.
    Species: Mouse
    Sample Type: Tissue Homogenates
  94. Deficiency of immunophilin FKBP52 promotes endometriosis.
    Authors: Hirota Y, Tranguch S, Daikoku T, Hasegawa A, Osuga Y, Taketani Y, Dey SK
    Am. J. Pathol., 2008;173(6):1747-57.
    Species: Mouse
    Sample Type: Peritoneal Fluid
  95. Heme oxygenase-1 promotes neovascularization in ischemic heart by coinduction of VEGF and SDF-1.
    Authors: Lin HH, Chen YH, Chang PF, Lee YT, Yet SF, Chau LY
    J. Mol. Cell. Cardiol., 2008;45(1):44-55.
    Species: Mouse
    Sample Type: Tissue Homogenates
  96. Inhibition of choroidal neovascularization with an anti-inflammatory carotenoid astaxanthin.
    Authors: Izumi-Nagai K, Nagai N, Ohgami K, Satofuka S, Ozawa Y, Tsubota K, Ohno S, Oike Y, Ishida S
    Invest. Ophthalmol. Vis. Sci., 2008;49(4):1679-85.
    Species: Mouse
    Sample Type: Tissue Homogenates
  97. VEGF-A produced by chronically inflamed tissue induces lymphangiogenesis in draining lymph nodes.
    Authors: Halin C, Tobler NE, Vigl B, Brown LF, Detmar M
    Blood, 2007;110(9):3158-67.
    Species: Mouse
    Sample Type: Tissue Homogenates
  98. von Hippel-Lindau mutation in mice recapitulates Chuvash polycythemia via hypoxia-inducible factor-2alpha signaling and splenic erythropoiesis.
    Authors: Hickey MM, Lam JC, Bezman NA, Rathmell WK, Simon MC
    J. Clin. Invest., 2007;117(12):3879-3889.
    Species: Mouse
    Sample Type: Serum
  99. Inactivation of VEGF in mammary gland epithelium severely compromises mammary gland development and function.
    Authors: Rossiter H, Barresi C, Ghannadan M, Gruber F, Mildner M, Fodinger D, Tschachler E
    FASEB J., 2007;21(14):3994-4004.
    Species: Mouse
    Sample Type: Milk
  100. Cathelicidin-deficient (Cnlp -/- ) mice show increased susceptibility to Pseudomonas aeruginosa keratitis.
    Authors: Huang LC, Reins RY, Gallo RL, McDermott AM
    Invest. Ophthalmol. Vis. Sci., 2007;48(10):4498-508.
    Species: Mouse
    Sample Type: Tissue Homogenates
  101. VEGF receptor inhibition slows the progression of polycystic kidney disease.
    Authors: Tao Y, Kim J, Yin Y, Zafar I, Falk S, He Z, Faubel S, Schrier RW, Edelstein CL
    Kidney Int., 2007;72(11):1358-66.
    Species: Mouse
    Sample Type: Serum
  102. Multiple circulating proangiogenic factors induced by sunitinib malate are tumor-independent and correlate with antitumor efficacy.
    Authors: Ebos JM, Lee CR, Christensen JG, Mutsaers AJ, Kerbel RS
    Proc. Natl. Acad. Sci. U.S.A., 2007;104(43):17069-74.
    Species: Mouse
    Sample Type: Plasma
  103. Soluble vascular endothelial growth factor receptor-1 protects mice in sepsis.
    Authors: Tsao PN, Chan FT, Wei SC, Hsieh WS, Chou HC, Su YN, Chen CY, Hsu WM, Hsieh FJ, Hsu SM
    Crit. Care Med., 2007;35(8):1955-60.
    Species: Mouse
    Sample Type: Plasma
  104. Very low density lipoprotein receptor, a negative regulator of the wnt signaling pathway and choroidal neovascularization.
    Authors: Chen Y, Hu Y, Lu K, Flannery JG, Ma JX
    J. Biol. Chem., 2007;282(47):34420-8.
    Species: Mouse
    Sample Type: Cell Culture Supernates
  105. HIF-1alpha induced-VEGF overexpression in bone marrow stem cells protects cardiomyocytes against ischemia.
    Authors: Dai Y, Xu M, Wang Y, Pasha Z, Li T, Ashraf M
    J. Mol. Cell. Cardiol., 2007;42(6):1036-44.
    Species: Mouse
    Sample Type: Cell Culture Supernates
  106. Macular pigment lutein is antiinflammatory in preventing choroidal neovascularization.
    Authors: Izumi-Nagai K, Nagai N, Ohgami K, Satofuka S, Ozawa Y, Tsubota K, Umezawa K, Ohno S, Oike Y, Ishida S
    Arterioscler. Thromb. Vasc. Biol., 2007;27(12):2555-62.
    Species: Mouse
    Sample Type: Tissue Homogenates
  107. A GMCSF and IL-15 fusokine leads to paradoxical immunosuppression in vivo via asymmetrical JAK/STAT signaling through the IL-15 receptor complex.
    Authors: Rafei M, Wu JH, Annabi B, Lejeune L, Francois M, Galipeau J
    Blood, 2007;109(5):2234-42.
    Species: Mouse
    Sample Type: Cell Culture Supernates
  108. Enteric bacteria and their antigens may stimulate postoperative peritoneal adhesion formation.
    Authors: Cahill RA, Wang JH, Redmond HP
    Surgery, 2007;141(3):403-10.
    Species: Mouse
    Sample Type: Peritoneal Lavage
  109. alpha2beta1 integrin expression in the tumor microenvironment enhances tumor angiogenesis in a tumor cell-specific manner.
    Authors: Zhang Z, Ramirez NE, Yankeelov TE, Li Z, Ford LE, Qi Y, Pozzi A, Zutter MM
    Blood, 2007;111(4):1980-8.
    Species: Mouse
    Sample Type: Cell Culture Supernates
  110. Effects of sustained antiangiogenic therapy in multistage prostate cancer in TRAMP model.
    Authors: Isayeva T, Chanda D, Kallman L, Eltoum IE, Ponnazhagan S
    Cancer Res., 2007;67(12):5789-97.
    Species: Mouse
    Sample Type: Serum
  111. Upregulation of VEGF in murine retina via monocyte recruitment after retinal scatter laser photocoagulation.
    Authors: Itaya M, Sakurai E, Nozaki M, Yamada K, Yamasaki S, Asai K, Ogura Y
    Invest. Ophthalmol. Vis. Sci., 2007;48(12):5677-83.
    Species: Mouse
    Sample Type: Tissue Homogenates
  112. Hypoxia-induced mitogenic factor has proangiogenic and proinflammatory effects in the lung via VEGF and VEGF receptor-2.
    Authors: Yamaji-Kegan K, Su Q, Angelini DJ, Champion HC, Johns RA
    Am. J. Physiol. Lung Cell Mol. Physiol., 2006;291(6):L1159-68.
    Species: Mouse
    Sample Type: Cell Culture Supernates
  113. Placenta growth factor in diabetic wound healing: altered expression and therapeutic potential.
    Authors: Cianfarani F, Zambruno G, Brogelli L, Sera F, Lacal PM, Pesce M, Capogrossi MC, Failla CM, Napolitano M, Odorisio T
    Am. J. Pathol., 2006;169(4):1167-82.
    Species: Mouse
    Sample Type: Tissue Homogenates
  114. Placental but not heart defects are associated with elevated hypoxia-inducible factor alpha levels in mice lacking prolyl hydroxylase domain protein 2.
    Authors: Takeda K, Ho VC, Takeda H, Duan LJ, Nagy A, Fong GH
    Mol. Cell. Biol., 2006;26(22):8336-46.
    Species: Mouse
    Sample Type: Tissue Homogenates
  115. CCL2 regulates angiogenesis via activation of Ets-1 transcription factor.
    Authors: Stamatovic SM, Keep RF, Mostarica-Stojkovic M, Andjelkovic AV
    J. Immunol., 2006;177(4):2651-61.
    Species: Mouse
    Sample Type: Cell Culture Supernates
  116. Albendazole: a potent inhibitor of vascular endothelial growth factor and malignant ascites formation in OVCAR-3 tumor-bearing nude mice.
    Authors: Pourgholami MH, Yan Cai Z, Lu Y, Wang L, Morris DL
    Clin. Cancer Res., 2006;12(6):1928-35.
    Species: Mouse
    Sample Type: Plasma
  117. Targeted deletion of CCR2 impairs deep vein thombosis resolution in a mouse model.
    Authors: Henke PK, Pearce CG, Moaveni DM, Moore AJ, Lynch EM, Longo C, Varma M, Dewyer NA, Deatrick KB, Upchurch GR, Wakefield TW, Hogaboam C, Kunkel SL
    J. Immunol., 2006;177(5):3388-97.
    Species: Mouse
    Sample Type: Tissue Homogenates
  118. Mast cells facilitate local VEGF release as an early event in the pathogenesis of postoperative peritoneal adhesions.
    Authors: Cahill RA, Wang JH, Soohkai S, Redmond HP
    Surgery, 2006;140(1):108-12.
    Species: Mouse
    Sample Type: Peritoneal Fluid
  119. Role of peroxisome proliferator-activated receptor-alpha in acute pancreatitis induced by cerulein.
    Authors: Genovese T, Mazzon E, Di Paola R, Muia C, Crisafulli C, Malleo G, Esposito E, Cuzzocrea S
    Immunology, 2006;118(4):559-70.
    Species: Mouse
    Sample Type: Tissue Homogenates
  120. Combination of systemic thioacetamide (TAA) injections and ethanol feeding accelerates hepatic fibrosis in C3H/He mice and is associated with intrahepatic up regulation of MMP-2, VEGF and ICAM-1.
    Authors: Kornek M, Raskopf E, Guetgemann I, Ocker M, Gerceker S, Gonzalez-Carmona MA, Rabe C, Sauerbruch T, Schmitz V
    J. Hepatol., 2006;45(3):370-6.
    Species: Mouse
    Sample Type: Tissue Homogenates
  121. High expression of ligands for chemokine receptor CXCR2 in alveolar epithelial neoplasia induced by oncogenic kras.
    Authors: Wislez M, Fujimoto N, Izzo JG, Hanna AE, Cody DD, Langley RR, Tang H, Burdick MD, Sato M, Minna JD, Mao L, Wistuba I, Strieter RM, Kurie JM
    Cancer Res., 2006;66(8):4198-207.
    Species: Mouse
    Sample Type: Tissue Homogenates
  122. Enalapril increases ischemia-induced endothelial progenitor cell mobilization through manipulation of the CD26 system.
    Authors: Wang CH, Verma S, Hsieh IC, Chen YJ, Kuo LT, Yang NI, Wang SY, Wu MY, Hsu CM, Cheng CW, Cherng WJ
    J. Mol. Cell. Cardiol., 2006;41(1):34-43.
    Species: Mouse
    Sample Type: Plasma
  123. Short-term dietary administration of celecoxib enhances the efficacy of tumor lysate-pulsed dendritic cell vaccines in treating murine breast cancer.
    Authors: Hahn T, Alvarez I, Kobie JJ, Ramanathapuram L, Dial S, Fulton A, Besselsen D, Walker E, Akporiaye ET
    Int. J. Cancer, 2006;118(9):2220-31.
    Species: Mouse
    Sample Type: Serum
  124. Hyperoxia causes angiopoietin 2-mediated acute lung injury and necrotic cell death.
    Authors: Bhandari V, Choo-Wing R, Lee CG, Zhu Z, Nedrelow JH, Chupp GL, Zhang X, Matthay MA, Ware LB, Homer RJ, Lee PJ, Geick A, de Fougerolles AR, Elias JA
    Nat. Med., 2006;12(11):1286-93.
    Species: Mouse
    Sample Type: BALF
  125. Increased VEGF levels induced by anti-VEGF treatment are independent of tumor burden in colorectal carcinomas in mice.
    Authors: Schmitz V, Vilanueva H, Raskopf E, Hilbert T, Barajas M, Dzienisowicz C, Gorschluter M, Strehl J, Rabe C, Sauerbruch T, Prieto J, Caselmann WH, Qian C
    Gene Ther., 2006;13(16):1198-205.
    Species: Mouse
    Sample Type: Tissue Homogenates
  126. Expression of pulmonary VEGF family declines with age and is further down-regulated in lipopolysaccharide (LPS)-induced lung injury.
    Authors: Ito Y, Betsuyaku T, Nagai K, Nasuhara Y, Nishimura M
    Exp. Gerontol., 2005;40(4):315-23.
    Species: Mouse
    Sample Type: BALF
  127. Adeno-associated virus vector-mediated delivery of pigment epithelium-derived factor restricts neuroblastoma angiogenesis and growth.
    Authors: Streck CJ, Zhang Y, Zhou J, Ng C, Nathwani AC, Davidoff AM
    J. Pediatr. Surg., 2005;40(1):236-43.
    Species: Mouse
    Sample Type: Tissue Homogenates
  128. The human herpes virus 8-encoded chemokine receptor is required for angioproliferation in a murine model of Kaposi's sarcoma.
    Authors: Jensen KK, Manfra DJ, Grisotto MG, Martin AP, Vassileva G, Kelley K, Schwartz TW, Lira SA
    J. Immunol., 2005;174(6):3686-94.
    Species: Mouse
    Sample Type: Tissue Homogenates
  129. Differential roles of vascular endothelial growth factor receptors 1 and 2 in dendritic cell differentiation.
    Authors: Dikov MM, Ohm JE, Ray N, Tchekneva EE, Burlison J, Moghanaki D, Nadaf S, Carbone DP
    J. Immunol., 2005;174(1):215-22.
    Species: Mouse
    Sample Type: Cell Culture Supernates
  130. Effect of valsartan versus lisinopril on peritoneal sclerosis in rats.
    Authors: Duman S, Sen S, Duman C, Oreopoulos DG
    Int J Artif Organs, 2005;28(2):156-63.
    Species: Rat
    Sample Type: Peritoneal Dialysate
  131. Nuclear factor-kappaB affects tumor progression in a mouse model of malignant pleural effusion.
    Authors: Stathopoulos GT, Zhu Z, Everhart MB, Kalomenidis I, Lawson WE, Bilaceroglu S, Peterson TE, Mitchell D, Yull FE, Light RW, Blackwell TS
    Am. J. Respir. Cell Mol. Biol., 2005;34(2):142-50.
    Species: Mouse
    Sample Type: Serum
  132. Recombinant adeno-associated virus 2-mediated antiangiogenic prevention in a mouse model of intraperitoneal ovarian cancer.
    Authors: Isayeva T, Ren C, Ponnazhagan S
    Clin. Cancer Res., 2005;11(3):1342-7.
    Species: Mouse
    Sample Type: Ascites Fluid
  133. Marked inhibition of retinal neovascularization in rats following soluble-flt-1 gene transfer.
    Authors: Rota R, Riccioni T, Zaccarini M, Lamartina S, Gallo AD, Fusco A, Kovesdi I, Balestrazzi E, Abeni DC, Ali RR, Capogrossi MC
    J Gene Med, 2004;6(9):992-1002.
    Species: Rat
    Sample Type: Vitreous Humor
  134. Estrogen regulates the production of VEGF for osteoclast formation and activity in op/op mice.
    Authors: Kodama I, Sanada M, Yoshiko Y, Tsuda M, Ohama K
    J. Bone Miner. Res., 2004;19(2):200-6.
    Species: Mouse
    Sample Type: Serum
  135. Metastatic squamous cell carcinoma cells that overexpress c-Met exhibit enhanced angiogenesis factor expression, scattering and metastasis in response to hepatocyte growth factor.
    Authors: Dong G, Lee TL, Yeh NT, Geoghegan J, Van Waes C
    Oncogene, 2004;23(37):6199-208.
    Species: Mouse
    Sample Type: Cell Culture Supernates
  136. VEGF164(165) as the pathological isoform: differential leukocyte and endothelial responses through VEGFR1 and VEGFR2.
    Authors: Usui T, Ishida S, Yamashiro K, Kaji Y, Poulaki V, Moore J, Moore T, Amano S, Horikawa Y, Dartt D, Golding M, Shima DT, Adamis AP
    Invest. Ophthalmol. Vis. Sci., 2004;45(2):368-74.
    Species: Mouse
    Sample Type: Tissue Homogenates
  137. beta-Catenin regulates vascular endothelial growth factor expression in colon cancer.
    Authors: Easwaran V, Lee SH, Inge L, Guo L, Goldbeck C, Garrett E, Wiesmann M, Garcia PD, Fuller JH, Chan V, Randazzo F, Gundel R, Warren RS, Escobedo J, Aukerman SL, Taylor RN, Fantl WJ
    Cancer Res., 2003;63(12):3145-53.
    Species: Mouse
    Sample Type: Tissue Homogenates
  138. A critical role of placental growth factor in the induction of inflammation and edema formation.
    Authors: Oura H, Bertoncini J, Velasco P, Brown LF, Carmeliet P, Detmar M
    Blood, 2002;101(2):560-7.
    Species: Mouse
    Sample Type: Cell Lysates
  139. Lack of alpha2-antiplasmin promotes pulmonary heart failure via overrelease of VEGF after acute myocardial infarction.
    Authors: Kozawa O, Yoshimi N, Akamatsu S, Hara A, Mori H, Uematsu T
    Blood, 2002;100(7):2487-93.
    Species: Mouse
    Sample Type: Cell Culture Supernates
  140. Recruitment of stem and progenitor cells from the bone marrow niche requires MMP-9 mediated release of kit-ligand.
    Authors: Heissig B, Hattori K, Dias S, Friedrich M, Ferris B, Hackett NR, Crystal RG, Besmer P, Lyden D, Moore MA, Werb Z, Rafii S
    Cell, 2002;109(5):625-37.
    Species: Mouse
    Sample Type: Plasma
  141. Gene transfer of transforming growth factor-beta1 to the rat peritoneum: effects on membrane function.
    Authors: Margetts PJ, Kolb M, Galt T, Hoff CM, Shockley TR, Gauldie J
    J. Am. Soc. Nephrol., 2001;12(10):2029-39.
    Species: Rat
    Sample Type: Peritoneal Fluid
  142. Antibodies to vascular endothelial growth factor enhance the efficacy of cancer immunotherapy by improving endogenous dendritic cell function.
    Authors: Gabrilovich DI, 2018, Ishida T, Nadaf S, Ohm JE, Carbone DP
    1537, 1999;5(10):2963-70.
    Species: Mouse
    Sample Type: Cell Culture Supernates
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