MRP6 Antibody (M6II-31)

Novus Biologicals | Catalog # NBP1-42343

Novus Biologicals
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Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen, Western Blot, Flow Cytometry, Immunocytochemistry/ Immunofluorescence

Label

Unconjugated

Antibody Source

Monoclonal Rat IgG2A Clone # M6II-31
View all MRP6 Primary Antibodies »

Product Specifications

Immunogen

MRP6 (aa 764-964)

Specificity

Does not cross-react with the human MDR1, MRP1, MRP2, MRP3, MRP4, MRP5 gene products.

Clonality

Monoclonal

Host

Rat

Isotype

IgG2A

Applications for MRP6 Antibody (M6II-31)

Application
Recommended Usage

Flow Cytometry

1:10-1:1000

Immunohistochemistry

1:20-1:50

Immunohistochemistry-Frozen

1:20-1:50

Immunohistochemistry-Paraffin

1:20-1:50

Western Blot

1:20-1:50
Application Notes
M6II-31 can be used to detect human MRP6 in cells and tissues. Immunocytochemistry: use 1:20-50 dilution on acetone fixed cytospin preparations. For immunohistochemistry: M6II-31 (use 1:20-50) on acetone fixed frozen sections can be followed by incubation

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Flow Cytometry

Formulation, Preparation, and Storage

Purification

Tissue culture supernatant

Formulation

Tissue culture supernatant, 0.7% BSA

Preservative

0.1% Sodium Azide

Concentration

This product is unpurified. The exact concentration of antibody is not quantifiable.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C. Do not freeze.

Background: MRP6

The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). The encoded protein, a member of the MRP subfamily, is involved in multi-drug resistance. Mutations in this gene cause pseudoxanthoma elasticum. Alternatively spliced transcript variants that encode different proteins have been described for this gene.

Alternate Names

Anthracycline resistance-associated protein, ARAPXE, ATP-binding cassette, sub-family C (CFTR/MRP), member 6, EST349056, MLP1ABC34, MOATE, MOAT-E, MRP6ATP-binding cassette sub-family C member 6, multidrug resistance-associated protein 6, Multi-specific organic anion transporter E, pseudoxanthoma elasticum, PXE1, URG7

Gene Symbol

ABCC6

Additional MRP6 Products

Product Documents for MRP6 Antibody (M6II-31)

Certificate of Analysis

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Product Specific Notices for MRP6 Antibody (M6II-31)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Protocols

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FAQs

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