Catalog Number: 6183
Chemical Name: (2S,4R,6E,8S)-8-[(2S,2'R,4'S,5R,5'S,7R,7'R,8R,9S,9'S,10'R)-9-Hydroxy-2,4',8,10'-tetramethyl-2'-[(2S,3S,5R,6R)-tetrahydro-6-hydroxy-6-(hydroxymethyl)-3,5-dimethyl-2H-pyran-2-yl]-9'-[[(2S,5S,6R)-tetrahydro-5
Biological Activity
Antiviral. Inhibits Zika virus entry in a range of cell types including primary placental fibroblast cells, HUVECs and UtMECs (IC50 values are 0.1, 0.4 and 0.97 μM in U2OS, HBMECs and Jeg-3 cells respectively). Also inhibits cellular uptake of West Nile, dengue, sindbis and chikungunya viruses.
Technical Data
  • M.Wt:
    889.1
  • Formula:
    C47H77NaO14
  • Solubility:
    Soluble to 100 mM in DMSO
  • Storage:
    Store at -20°C
  • CAS No:
    65101-87-3
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. Screening Bioactives Reveals Nanchangmycin as a Broad Spectrum Antiviral Active against Zika Virus.
    Rausch et al.
    Cell Rep., 2017;18:804
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