Native Lipoteichoic Acid Antibody (55)

Novus Biologicals | Catalog # NBP2-62811

Novus Biologicals
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Key Product Details

Species Reactivity

Bacteria

Applications

Immunohistochemistry, Immunohistochemistry-Frozen, Western Blot, Immunoassay, Flow Cytometry, Immunocytochemistry/ Immunofluorescence

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG3 Clone # 55
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Product Specifications

Immunogen

Microbial mixture of Streptococcus sobrims HG961, HG962, HG970 and HG977

Clonality

Monoclonal

Host

Mouse

Isotype

IgG3

Applications for Native Lipoteichoic Acid Antibody (55)

Application
Recommended Usage

Flow Cytometry

1:10-1:1000

Immunocytochemistry/ Immunofluorescence

1:10-1:500

Immunohistochemistry-Frozen

1:10-1:500

Western Blot

1:100-1:2000

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Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

PBS with 0.1% BSA

Preservative

0.02% Sodium Azide

Concentration

0.1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C.

Background: Native Lipoteichoic Acid

The monoclonal antibody 55 recognizes lipoteichoic acid (LTA). LTA, a glycerol phosphate surface polymer, is a component of the envelope of Gram-positive bacteria. LTA is anchored via its glycolipids to the membrane and carries a polysaccharide chain extending into the peptidoglycan layer of the cell wall. LTA is released spontaneously into the culture medium during growth of gram-positive bacteria. LTA functions as an immune activator with characteristics very similar to lipopolysaccharide (LPS) from Gram-negative bacteria. LTA binds to CD14 and triggers activation predominantly via Toll-like receptor 2. Although LTA is internalized and traffics to the Golgi, the cellular activation in response to LTA occurs at the cell surface.

Alternate Names

LTA

Additional Native Lipoteichoic Acid Products

Product Documents for Native Lipoteichoic Acid Antibody (55)

Certificate of Analysis

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Product Specific Notices for Native Lipoteichoic Acid Antibody (55)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Protocols

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