NBD 556

Catalog # Availability Size / Price Qty
5811/10
5811/50
Cat.No. 5811 - NBD 556 | C17H24ClN3O2 | CAS No. 333353-44-9
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Description: CD4 mimetic; blocks HIV-1 cell entry

Chemical Name: N1-(4-Chlorophenyl)-N2-(2,2,6,6-tetramethyl-4-piperidinyl)ethanediamide

Purity: ≥98%

Product Details
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Biological Activity

CD4 mimetic (IC50 values are in low micromolar range, dependent on cell type and HIV strain). Recognizes and induces structural changes in HIV-1 envelope protein gp120, analogous to CD4 binding. Inhibits HIV-1 cell entry in CXCR4 and CCR5 expressing cell lines, by blocking virus-cell and cell-cell fusion.

Technical Data

M.Wt:
337.84
Formula:
C17H24ClN3O2
Solubility:
Soluble to 100 mM in DMSO and to 20 mM in ethanol
Purity:
≥98%
Storage:
Store at +4°C
CAS No:
333353-44-9

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.

Product Datasheets

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