Nectin-2/CD112 Antibody (BLR071G)

Novus Biologicals | Catalog # NBP3-14684

Recombinant Monoclonal Antibody
Novus Biologicals
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Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry, Western Blot, Immunocytochemistry/ Immunofluorescence

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit Clone # BLR071G
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Product Specifications

Immunogen

between 50 and 100

Clonality

Monoclonal

Host

Rabbit

Scientific Data Images for Nectin-2/CD112 Antibody (BLR071G)

Nectin-2/CD112 Antibody (BLR071G)

Western Blot;Nectin-2/CD112 Antibody (BLR071G)[NBP3-14684]

Western Blot;Nectin-2/CD112 Antibody (BLR071G) Whole cell lysate (50 µg) from OVCAR-8, Jurkat, U2OS, GaMG, OVCAR-4, 786-O, A-549, and SK-MEL-28 cells prepared using NETN lysis buffer. Antibody: Rabbit anti-Nectin-2/CD112 recombinant monoclonal antibody used at 1:1000. Secondary: HRP-conjugated goat anti-rabbit IgG. Detection: Chemiluminescence with an exposure time of 30 seconds. Lower panel: Rabbit anti-GAPDH.

Applications for Nectin-2/CD112 Antibody (BLR071G)

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

Optimal dilutions of this antibody should be experimentally determined.

Immunohistochemistry

Optimal dilutions of this antibody should be experimentally determined.

Western Blot

Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

>95%

Formulation

Borate Buffered Saline (BBS) pH 8.2 with, BSA Free

Preservative

0.09% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 2 - 8 C / 1 year from date of receipt

Background: Nectin-2/CD112

Nectin 2 encodes a single-pass type I membrane glycoprotein with two Ig-like C2-type domains and an Ig-like V-type domain. This protein is one of the plasma membrane components of adherens junctions. It also serves as an entry for certain mutant strains of herpes simplex virus and pseudorabies virus, and it is involved in cell to cell spreading of these viruses. Variations in this gene have been associated with differences in the severity of multiple sclerosis. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Long Name

Poliovirus Receptor Related 2

Alternate Names

CD112, HVEB, MPH, Nectin2, PRR2, PVRL2

Gene Symbol

NECTIN2

Additional Nectin-2/CD112 Products

Product Documents for Nectin-2/CD112 Antibody (BLR071G)

Certificate of Analysis

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Product Specific Notices for Nectin-2/CD112 Antibody (BLR071G)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Protocols

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