Neprilysin/CD10 Antibody (2A1H5E1) - BSA Free

Name: Neprilysin/CD10 Antibody (2A1H5E1) - BSA Free
Brand: Novus Biologicals
SKU: NBP1-47356
Price: 139 USD
Availability: InStock

Novus Biologicals | Catalog # NBP1-47356

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Product Specifications
Scientific Data
Applications
Preparation & Storage
Background
Product Documents
Specific Notices
Research Areas

Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, ELISA

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG_2B Clone # 2A1H5E1

Format

BSA Free

View all Neprilysin/CD10 Primary Antibodies »

Product Specifications

Immunogen

Purified recombinant fragment of human CD-10 expressed in E. Coli.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG_2B

Scientific Data Images for Neprilysin/CD10 Antibody (2A1H5E1) - BSA Free

Immunohistochemistry-Paraffin: Neprilysin/CD10 Antibody (2A1H5E1) - BSA Free [NBP1-47356]

Immunohistochemistry-Paraffin: Neprilysin/CD10 Antibody (2A1H5E1) [NBP1-47356] - Analysis of human breast ductal myoepithelium (A) and lymph tissue (B), showing cytoplasmic (A) and membrane (B) localization using CD10 mouse mAb with DAB staining (A) and AEC staining (B).

Applications for Neprilysin/CD10 Antibody (2A1H5E1) - BSA Free

Application

Recommended Usage

ELISA

1:10000

Immunohistochemistry

1:10 - 1:500

Immunohistochemistry-Paraffin

1:200 - 1000

Formulation, Preparation, and Storage

Purification

Ascites

Formulation

Ascitic fluid

Format

BSA Free

Preservative

0.03% Sodium Azide

Concentration

This product is unpurified. The exact concentration of antibody is not quantifiable.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Neprilysin/CD10

This antibody recognizes human CD10 (CALLA, NEP, enkephalinase, Neprilysin), which is a 100 kDa, type II cell surface glycoprotein originally identified for its expression on most acute lymphoblastic leukemias (ALL). Subsequently, CD10 was shown to be the same molecule as the neutral endopeptidase (NEP), or KII-NA. CD10 is a Zn2+-dependent metallo-peptidase with endothelin, glucagon, gastrin, neurotensin and bradykinin included among its substrates. CD10 is involved in the regulation of chemotactic and inflammatory processes involving neutrophils. In B cells, CD10 regulates stromal cell-dependent B lymphopoiesis and expression has also been reported on mature B cells in germinal centres. In addition to the hematopoietic compartment, other major sites of CD10 expression are the brush border of enterocytes and renal tubules and glomeruli. There is partial blocking of CB-CALLA and MEM-78 monoclonal antibodies indicating that they recognize similar epitopes.

Alternate Names

CALLA, CD10, Enkephalinase, Leu-19, MME, Neutral Endopeptidase 24.11, NKH1

Entrez Gene IDs

4311 (Human)

Gene Symbol

MME

Additional Neprilysin/CD10 Products

Product Documents for Neprilysin/CD10 Antibody (2A1H5E1) - BSA Free

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Product Specific Notices for Neprilysin/CD10 Antibody (2A1H5E1) - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.