Neuritin Antibody - BSA Free

Novus Biologicals | Catalog # NBP1-77282

Novus Biologicals
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Key Product Details

Species Reactivity

Validated:

Human, Mouse

Predicted:

Bovine (100%), Rat (100%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot, ELISA, Immunocytochemistry/ Immunofluorescence

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free
View all Neuritin Primary Antibodies »

Product Specifications

Immunogen

Antibody was raised against a 20 amino acid synthetic peptide from near the center of human neuritin. The immunogen is located within amino acids 70 - 120 of Neuritin. Amino Acid Squence: CQEGAKDMWDKLRKESKNLN

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

15 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for Neuritin Antibody - BSA Free

Western Blot: Neuritin AntibodyBSA Free [NBP1-77282]

Western Blot: Neuritin AntibodyBSA Free [NBP1-77282]

Western Blot: Neuritin Antibody [NBP1-77282] - Analysis of neuritin in Daudi cell lysate with neuritin antibody at (A) 5 and (B) 10 ug/mL.
Neuritin Antibody - BSA Free

Immunocytochemistry/ Immunofluorescence: Neuritin Antibody - BSA Free [NBP1-77282] -

Immunocytochemistry/ Immunofluorescence: Neuritin Antibody - BSA Free [NBP1-77282] - Immunofluorescence of Neuritin in human brain tissue with Neuritin antibody at 20 ug/mL.

Green: Neuritin Antibody
Blue: DAPI staining
Neuritin Antibody - BSA Free

Immunohistochemistry: Neuritin Antibody - BSA Free [NBP1-77282] -

Immunohistochemistry: Neuritin Antibody - BSA Free [NBP1-77282] - Immunohistochemistry of Neuritin in mouse heart tissue with Neuritin antibody at 5 ug/mL.
Neuritin Antibody - BSA Free

Immunohistochemistry: Neuritin Antibody - BSA Free [NBP1-77282] -

Immunohistochemistry: Neuritin Antibody - BSA Free [NBP1-77282] - Immunohistochemistry of Neuritin in human brain tissue with Neuritin antibody at 2.5 ug/ml.
Neuritin Antibody - BSA Free

Immunocytochemistry/ Immunofluorescence: Neuritin Antibody - BSA Free [NBP1-77282] -

Immunocytochemistry/ Immunofluorescence: Neuritin Antibody - BSA Free [NBP1-77282] - Immunofluorescence of Neuritin in Mouse Heart cells with Neuritin antibody at 20 ug/mL.

Applications for Neuritin Antibody - BSA Free

Application
Recommended Usage

ELISA

1:100-1:2000

Immunocytochemistry/ Immunofluorescence

20 ug/mL

Immunohistochemistry

2.5 ug/ml

Immunohistochemistry-Paraffin

2.5 ug/ml

Western Blot

5-10 ug/ml

Formulation, Preparation, and Storage

Purification

Peptide affinity purified

Formulation

PBS

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Neuritin

As the nervous system of a complex organism develops, it establishes functional networks through the growth and retraction of synaptic connections from growing axons and dendrites. This synaptic remodeling involves neuro-transmitter signaling, activation of neurotrophin receptors and alterations in gene expression. One such gene whose expression is increased by neural activity is neuritin, a GPI-anchored protein that is expressed in postmitotic differentiating neurons of the developing nervous system. Its expression is also induced by the neurotrophins BDNF and NT-3. Purified recombinant neuritin promotes neurite outgrowth and arborization in primary embryonic neuronal cultures, suggesting that neuritin may play a role as a downstream effector of activity-induced neurite outgrowth. More recent experiments have shown that neuritin is required for the androgen-induced axonal elongation in motor neurons and is upregulated following spinal cord injury, suggesting that neuritin may also play a role in survival and axonal regeneration.

Alternate Names

NRN1

Gene Symbol

NRN1

UniProt

NP_057672

Additional Neuritin Products

Product Documents for Neuritin Antibody - BSA Free

Certificate of Analysis

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Product Specific Notices for Neuritin Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Related Research Areas

Ion Channels and Regulators

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Protocols

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FAQs

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