NU 2058

Catalog # Availability Size / Price Qty
3135/10
3135/50
NU 2058 | CAS No. 161058-83-9 | Cyclin-dependent Kinase Inhibitors
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Description: Cdk1 and cdk2 inhibitor

Chemical Name: 6-(Cyclohexylmethoxy)-9H-purin-2-amine

Purity: ≥99%

Product Details
Citations (1)
Reviews

Biological Activity

Cyclin-dependent kinase (cdk) 1 and cdk2 inhibitor (Ki values are 5 and 12 μM respectively). Inhibits growth of human tumor cells in vitro (mean GI50 = 13 μM). Also inhibits DNA topoisomerase II ATPase activity (IC50 = 300 μM).

Technical Data

M.Wt:
247.3
Formula:
C12H17N5O
Solubility:
Soluble to 100 mM in DMSO and to 10 mM in ethanol
Purity:
≥99%
Storage:
Store at +4°C
CAS No:
161058-83-9

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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Citation for NU 2058

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