Chemical Name: 1,3-Dimethoxy-5-methyl-2-[(1R,6R)-3-methyl-6-(1-methylethenyl)-2-cyclohexen-1-yl]benzene
Biological ActivityO-1918 is a selective, silent antagonist of a putative endothelial anandamide receptor distinct from CB1 or CB2 receptors. Inhibits vasodilation and cell migration induced by abnormal-cannabidiol (abn-CBD; Cat. No. 1297).
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Selective ligands and cellular effectors of a G protein-coupled endothelial cannabinoid receptor.
Offert?ler et al.
Atypical cannabinoid stimulates endothelial cell migration via a Gi/Go coupled receptor distinct from CB1, CB2 or EDG-1.
Mo et al.
Vasorelaxant effects of oleamide in rat small mesenteric artery indicate action at a novel cannabinoid receptor.
Hoi and Hiley
Citations for O-1918
The citations listed below are publications that use Tocris products. Selected citations for O-1918 include:
3 Citations: Showing 1 - 3
Up-regulation of heme oxygenase-1 expression and inhibition of disease-associated features by cannabidiol in vascular smooth muscle cells.
Authors: Schwartz Et al.
Abnormal cannabidiol attenuates experimental colitis in mice, promotes wound healing and inhibits neutrophil recruitment.
Authors: Krohn Et al.
J Inflamm (Lond) 2016;13:21
Characterization of the vasorelaxant mechanisms of the endocannabinoid anandamide in rat aorta.
Authors: Herradón Et al.
Br J Pharmacol 2007;152:699
No product specific FAQs exist for this product, however you mayView all Small Molecule FAQs
Tocris Small Molecules
Reviews for O-1918
There are currently no reviews for this product. Be the first to review O-1918 and earn rewards!
Have you used O-1918?
Submit a review and receive an Amazon gift card.
$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image