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O-1918

2288 3 Citations Datasheet / COA / SDS
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2288/10
O-1918 | CAS No. 536697-79-7 | Additional Cannabinoid-related Compounds
1 Image
Description: Silent antagonist for putative abnormal-CBD (Cat. No. 1297) receptor

Chemical Name: 1,3-Dimethoxy-5-methyl-2-[(1R,6R)-3-methyl-6-(1-methylethenyl)-2-cyclohexen-1-yl]benzene

Purity: ≥97%

Product Details
Citations (3)
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Biological Activity Technical Data Additional Information Background Product Datasheets Calculators

Biological Activity

O-1918 is a selective, silent antagonist of a putative endothelial anandamide receptor distinct from CB1 or CB2 receptors. Inhibits vasodilation and cell migration induced by abnormal-cannabidiol (abn-CBD; Cat. No. 1297).

Technical Data

M.Wt:
286.41
Formula:
C19H26O2
Solubility:
Soluble to 100 mM in DMSO and to 100 mM in ethanol
Purity:
≥97%
Storage:
Store at -20°C
CAS No:
536697-79-7

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Additional Information

Licensing Caveats:
Sold under license from the NIH, US patent 60/312,674

Product Datasheets

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Citations for O-1918

The citations listed below are publications that use Tocris products. Selected citations for O-1918 include:

3 Citations: Showing 1 - 3

  1. Up-regulation of heme oxygenase-1 expression and inhibition of disease-associated features by cannabidiol in vascular smooth muscle cells.
    Authors: Schwartz Et al.
    Oncotarget  2018;9:34595
  2. Abnormal cannabidiol attenuates experimental colitis in mice, promotes wound healing and inhibits neutrophil recruitment.
    Authors: Krohn Et al.
    J Inflamm (Lond)  2016;13:21
  3. Characterization of the vasorelaxant mechanisms of the endocannabinoid anandamide in rat aorta.
    Authors: Herradón Et al.
    Br J Pharmacol  2007;152:699

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Tocris Small Molecules

Abn-CBD

1297
3 Citations
1 Image

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