Chemical Name: 1,3-Dimethoxy-5-methyl-2-[(1R,6R)-3-methyl-6-(1-methylethenyl)-2-cyclohexen-1-yl]benzene
Biological ActivitySelective, silent antagonist of a putative endothelial anandamide receptor distinct from CB1 or CB2 receptors. Inhibits vasodilation and cell migration induced by abnormal-cannabidiol (abn-CBD; Cat. No. 1297).
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Tocris products are intended for laboratory research use only, unless stated otherwise.
Selective ligands and cellular effectors of a G protein-coupled endothelial cannabinoid receptor.
Offert?ler et al.
Atypical cannabinoid stimulates endothelial cell migration via a Gi/Go coupled receptor distinct from CB1, CB2 or EDG-1.
Mo et al.
Vasorelaxant effects of oleamide in rat small mesenteric artery indicate action at a novel cannabinoid receptor.
Hoi and Hiley
Citations for O-1918
The citations listed below are publications that use Tocris products. Selected citations for O-1918 include:
3 Citations: Showing 1 - 3
Up-regulation of heme oxygenase-1 expression and inhibition of disease-associated features by cannabidiol in vascular smooth muscle cells.
Authors: Schwartz Et al.
Abnormal cannabidiol attenuates experimental colitis in mice, promotes wound healing and inhibits neutrophil recruitment.
Authors: Krohn Et al.
J Inflamm (Lond) 2016;13:21
Characterization of the vasorelaxant mechanisms of the endocannabinoid anandamide in rat aorta.
Authors: Herradón Et al.
Br J Pharmacol 2007;152:699
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