p53 Antibody [mFluor Violet 450 SE]

Name: p53 Antibody [mFluor Violet 450 SE]
Brand: Novus Biologicals
SKU: NB200-171MFV450
Price: 599 USD
Availability: InStock

Novus Biologicals | Catalog # NB200-171MFV450

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Product Specifications
Scientific Data
Applications
Preparation & Storage
Background
Product Documents
Specific Notices
Research Areas
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Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry, Chromatin Immunoprecipitation Sequencing

Label

mFluor Violet 450 SE (Excitation = 406 nm, Emission = 445 nm)

Antibody Source

Polyclonal Rabbit IgG

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Product Specifications

Immunogen

The immunogen this antibody was made to, maps to a region between residues 50-100 of human tumor protein p53 using the SwissProt entry P04637 (GeneID 7157).

Localization

Cytoplasmic and nuclear

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for p53 Antibody [mFluor Violet 450 SE]

p53 Antibody [mFluor Violet 450 SE] [NB200-171MFV450] -

p53 Antibody [mFluor Violet 450 SE] [NB200-171MFV450] - Vial of mFluor Violet 450 conjugated antibody. mFluor Violet 450 is optimally excited at 406 nm by the Violet laser (405 nm) and has an emission maximum of 445 nm.

Applications for p53 Antibody [mFluor Violet 450 SE]

Application

Recommended Usage

Chromatin Immunoprecipitation Sequencing

Optimal dilutions of this antibody should be experimentally determined.

Immunohistochemistry

Optimal dilutions of this antibody should be experimentally determined.

Application Notes

Optimal dilution of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

50mM Sodium Borate

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: p53

p53 is a stress-regulated transcription factor that was first identified as an SV40 large T antigen-binding protein. It plays a major role in the cellular response to DNA damage and other genomic aberrations. The activation of p53 can lead to either cell cycle arrest and DNA repair, or apoptosis. p53 is phosphorylated at multiple sites in vivo and by several different protein kinases in vitro. Mutation of p53 is the most common genetic change so far identified in a number of major carcinomas. This antibody can be used for the specific detection of human p53 that is synthesized in the presence of p53 from other species.

Alternate Names

BCC7, LFS1, TP53, TRP53

Gene Symbol

TP53

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Product Specific Notices for p53 Antibody [mFluor Violet 450 SE]

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.